What Dilaudid Is Similair

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equivilency of roxicodone 30 mg

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An equivalent dose of Dilaudid/Hydromorphone would be 11.25mgs.

https:/­/­www.medschat.com/­wiki/­Diluadid/­

https:/­/­www.medschat.com/­wiki/­Roxicodone/­

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Wow som1 who actually knows there conversion rates... 30mg oxicodone = to 29mg hydrocodone = to 60 mg of morphine = to 20mg meathadone = to 20mg oximorphone = to 12mg hydromorphone = to 600mcg fyntynal = to 30mg diamorphine, remember all these drugs have different boiavalabilties like oxicodone is 90% and hydromorphone oraly has a bio availability of 30-35% thats why it sucks. oraly bio is same. Through rectal and through nasle passage the bio is 55% and iv is 100%, tho bioavalibility varies wildly oraly from 10% to 60%, also hydromorphone is 60 times stronger than morphine when administered via iv. Morphine's bioavailability is 20 to 40% orally and 36 to 71% rectaly and 100% iv. So in order to = 30mg of oral oxicodone with morphine technicaly would be dubble 60mg but take into acount the bioavailability and you would be at 100 to 150mg of oral morphine thats why alot of peaple go into withdrawal when switched from oxi hydromorphone the conversion charts are based on protein binding once in the body and the chemical stucture of the drug oximorphone has bio of 10% oral 40% nasle 100% iv / fentynal bio is 33% oral / 50% buccal /nasle 89% / iv 92% hydrocodone bio is similar to oxicodone and high in every meathod and is converted to hydromorphone extremely quick one in the body.

Now that we have covered convertion charts and bioavalibility ie how much drug enters your body through various routes of administration, now you have protein binding which means how much of the drug is going to bind to the target receptor. hydrocodone has low receptor binding but has high bioavailability whereas morphine has low bioavailability oraly but high protein binding. once inside the body protein binding for hydromorphone is somewhat low at 20%, so combine a bad oral bioavalibility with bad protein binding and you get vary little effect nasle or iv. Its a great drug, best pain relief out of any of the opioids im prescribed, morphine sulphate 60mg ms contins and oxi codone 15 mg. The oxi 15 affects me more than the morphine 60mg when morphine is taken oraly, but now iv switched to rectal administration compounding pills into viscus liquid of 10mg/ml. but i just do 30mg rectal solution every 4 hours instead of 60mg oral evey 8 hours and ill tell you that 30mg of rectal morphine is about equal now to the effects of 15mg oral oxicodone. also they do prescribe morphine sopositories 30mg max strength but taking the morphine rectaly leaves me with about 20 extra 60s. Anyways, you can see how it can get pretty complicated when converting from one opioid to another.

I recomend the fentynal patches or oxycodone, hydrocodone, hydromorphone, also oxymorphone. Yes oral oxymorphone has low bioavailability % and low protien binding 10%, but they're both stable 10% so you just give a bigger dose for opioid pain relief. You want to look for an opioid with a stable bioavailability. They dont swing from one side of the spectrum to the other. The same dose ends up in your brain every time you dose and does not fluctuate; like morphine fluctuations can cause withdrawal symptoms, overdosing, nausea, and all the symptoms associated with opioids. The less fluctuations in boiavalabilties the better and the less symptoms you will have.

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