Wellbutrin, Bupropion, Buprop 24 Xl

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Don B Says:


I took Wellbutrin and Wellbutrin XL for several years. It worked well for depression. I was then switched to the generic, Bupropion Hcl XL. This also worked well. I was then switched to "Buprop 24 XL". After a month or so, I had serious side effects. (Muscle spasms, increased depression, and my hands shook such that it affected my writing and the use of a keyboard.) About 2 months ago I switched back to the brand drug, Wellbutrin, and am almost back to normal.

If Buprop 24 XL is identical to Wellbutrin (and to Bupropion), why the side effects? What companies make each of the three different drugs?



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Verwon Says:

Well to be honest, the generics and name brands aren't necessarily identical. I know they tell you that and they do so because for most people, it doesn't make a difference. They can freely switch from one to the other and not suffer any problematic issues.

However, the generics are allowed to differ from the name brand by as much as plus or minus 20% of the active ingredient. The FDA considers this to be an acceptable therapeutic window and, as I've already stated, for most people it is a very slight fluctuation that doesn't cause any problems, at all.

However, there is a very small percentage of people that can be sensitive to any slight difference in a medication. I suffer from very similar issues myself and have had to switch several times, when my pharmacy started carry the generic from a different manufacturer and it caused me problems.

Learn more Wellbutrin details here.

The best suggestion I can make to avoid the problem in the future is to ask your doctor to write your prescription as 'brand medically necessary.'

Is there anything else I can help with?


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Don B Says:

Thanks for the reply. I have switched to the brand name. Unfortunately, in this case, we're talking about hundreds of dollars difference.


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mollies Says:
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Wellbutrin xl 300mg ive been on this for about a year. With nuzak. Wellbutrin seems to work for me. no real side effects.

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