Tramadol By Amneal Vs Mylan (Top voted first)

All our pharmacies here have switched to amneal, which doesn't do a thing except give a headache. The brand does make a difference. The mylan works great.

REPLY

REPORT

I have Celiac & have been gluten free for 5 years. They say the Amneal are gluten free but I'm having a terrible reaction to it. I have joint pain like I have with gluten & I've become depressed & so sleepy that I can't work. My pharmacy is going to get Teva in for me. I just have to pay out of pocket for them. I've had Mylan before & never had any problems. Amneal brand is questionable.

REPLY

Was this helpful? 13

Your not crazzzzy THE GENERICS ARE BEING MESSED WITH BY THE FDA PERIOD..... IVE SEEN IT IN SEVERAL MEDICATIONS.... IM 42 YEARS OLD AND I KKOW MY BODY...... SOMETHING is GOING ON AND THE GOVERNMENT Is MESSING WITH THE ACTIVE INGREDIENT IN ALL. GENERIC MEDS....

REPLY

Was this helpful? 13

Yes, there can be differences in generic medications. Once a medication is available to be made a generic, it is allowed to differ, in the active ingredient, from the name brand by as much as plus or minus 20%. The FDA considers this an acceptable therapeutic window.

The problem that you can run into, of course, is that generics do not have to measure against each other, just against the name brand.

This means that while one generic may be high quality and contain 100mgs of a given medication, another generic may only contain 80mgs and another could contain 120mgs.

Not everyone is sensitive to such changes and most people don't even notice, however, there are some people that do have problems when they switch from a name brand to a generic, or from generic to another.

REPLY

Was this helpful? 12

Brandon, I "know" that Generics companies are now producing medications that are even below substandard in quality and benefits. The companies that produce them obviously do not fear that the FDA will actually check enough samples to tell the difference. And, IF the FDA is conducting reviews they, themselves, must be doing a substandard job and are not comparing the Generics formulas to the brand name formulas. The Generic companies are substituting essential components of the medications (I know it's true for tramadol, gabapentin, & clonidine) with something that is far from what made the original formulas beneficial enough to be approved, by the FDA, for the Brand Name. Or, the are omitting it all together. In any case they have basically been producing "knock off" medications with fake substandard, nonbeneficial ingredients. I know several people with very serious issues who are having weird problems with generic medications that they didn't have before, and like some of us, tested them against their left over meds of the same generic brand and have experienced extreme differences between them. Someone mentioned, on this feed, or another, that some of our generic meds are now being made in mass quantity, in other countries like India, who have no loyalty to, or concern for the health and welfare of American citizens. If that's true, we have ALL been downgraded to substandard welfare style healthcare in America. If anyone know if anyone has started some kind of group FDA complaint, I would like to add my name on it. I'm sure that many others would too.

REPLY

Was this helpful? 10

You're right Jackie, and some of them are causing very dangerous side effects. I take tramadol for spinal stenosis, osteo arth., and the pains that they cause in legs, back, joints, etc. At first I was given codones, hydrocodone, oxycodone, etc. But the "high" from codones were restricting me too much. In about 2002, and again in 2005, I broke bones in my feet, the 5th metatarsal in each one. Anyway, I asked my doctor for an alternative to a codones and he prescribed Ultracet. It was great because I was able to get relief and still function because it didn't cause any weirdness. Each time I took it for about 6 months. After that, in 2008, I suffered a vision loss, my site is now 20/400, and very distorted with no visual acuity, which caused many life changes, including the ability to drive. I was too young to settle into being completely restricted so I began to learn to walk, ride the bus, etc. Consequently, pains that I never felt before started manifesting, my left leg would go numb and "disappear", pains in elbows, shoulders, knees, etc., all " woke" up. After the analysis I was diagnosed with severe stenosis in my spine, osteo arthritis, Morton's neuromas in both feet, damaged knees. (I was an outside technician when I worked) Anyway, I besides not wanting the weirdness I felt with the codones, I, now, also had an equilibrium problem, so requested tramadol and naprosyn for pain, instead of the codones, and it controlled the pain fairly well, without causing further disruption in my functional abilities. I was able to cut down on the prescribed doses, so I always had a few left, which I saved each month. About 2 or so, years ago, I noticed that the tramadol was causing me to become depressed. There was no other reason for it, but to be sure I went ahead and took some of the tramadol I had saved, from older scripts, and the depression stopped. The next month, I switched to a different drug store of the same pharmacy group, to see if it was a bad batch.

The depression started again, only this time it also caused "unwanted and increased thoughts", which interfered with sleep, concentration, etc. The next month, I switched to a different pharmacy "group", this time the tramadol caused my feelings to be " gone", I felt stifled and indifferent. I tried to go without the tramadol, but I was unable to just stop. My heart started palpitating very fast, I was panicky, my body felt like it was becoming a gnarled cramp. I talked to my doctor and he offered to switch me to a codones, or methadone, but I decided to try different pharmacies again instead. Since then I have tried 6 pharmacies, and have had problems ranging from depression, and indifference, to animosity, impatience and anger about even the smallest things, like not having any lettuce. I finally returned to the original pharmacy and even though they say not to, because of the similarities in the components, I have had to counter the side effects with anti-depressants, or anti-anxiety meds. I have had nothing, NO, negative drug interaction. I know the "tramadol" formula that is being dispensed throughout (my city anyway) has been tampered with at the production level. At one point the script that I picked up caused bad thoughts and hostile feelings. I was able to work through this logically because my emotions were affected from a physical standpoint and not because of any circumstances, but it is still miserable. Lately the scripts have not been as bad, they remove the pain, but they still cause similar side affects, so I don't know what to do except consider going the metadone route for the pain :( Does anyone know if there are any group complaint actions with the FDA about the substandard medication that the generic companies are pumping out? I can only imaging what's happening to those with life and death situations who must rely on their medications to work.

REPLY

Was this helpful? 9

walmart carries the mylan but I get no results at all from it. Walgreens carries Zydus for tramadol and I find it is the best I have ever tired and kills my pain so much quicker. I couldn't get it so I am now tying the teva form CVS I hope it works as well because it is 125 w/o ins where my at Walgreens using my card from them its 15 dollars for the same amount of 180 tramadol so that killed me but what are going ot do. Hope my replies helps someone and good luck to everyone is so much better than taking those really hard narcotics. don't get wrong the tramadol are addicting for me though I take a subscribed cause they work and I don't feel any high off them. Thank the good Lord above Amen.

REPLY

Was this helpful? 8

Amneal (aka 627's) are absolutely HORRIBLE! I had been taking tramadol 2x/day in the am and occasionally 2 in the afternoon for 6 months with no ill side effects. I then picked up my prescription and the pills were different. I thought nothing of it until I actually took a dose of my usual 2 and I barely felt any pain relief, I didn't get the usual energy associated with my previous tramadol use, and my mood went hostile and complacent instead of happy like the tramadol normally use to make me.

The long oblong pills were the best I have taken so far. Consistently effective...this amneal garbage should be pulled from the market.

REPLY

Was this helpful? 9

Hate to say it guys but i've been on Mylan for several years and it has always worked but the last two prescriptions havent worked. They must have changed their formula. To prove it i have some of the older ones I've saved over time and i can take them and they work just fine. Now my dilema is finding a brand that does work or pay the extra cost for Ultram.

REPLY

Was this helpful? 5

There is also a difference in inactive ingredients. The one that makes the biggest difference in generics is the "disintegrating agent." This is something that attracts liquid and causes the pill to fall apart, so the active ingredients can be metabolized. If one generic uses a less effective (cheaper) disintegrating ingredient, the pill can be in larger clumps and just pass through the GI tract without as much actually being metabolized. So, when someone tells you that there is no difference between generic and brand names, well, that isn't really accurate when comparing all ingredients. When the comparison is only between active ingredients, there isn't a lot of difference. But bioavailability can differ greatly that is caused by the inactive ingredients. If one doesn't work as well for you, pay attention to that and request a different manufacturer. It's your health.

REPLY

Was this helpful? 5

I have been using Tramadol HCL for about 5 years. I started by using the Generic I got at Rite Aid (Teva) and it works just great for me. However my physician called my last prescription in to WalMart and I got (Mylan) which does absolutely nothing for my pain. It's a waste of money. So I have ask my physician to specifically order from Rite Aid or if I get the prescription I take it there myself.

REPLY

Was this helpful? 5

Mylan makes me sick as a dog in fact It makes me so ill Im sure if I kept taking it after 2 days It would have killed me. I'm considering a legal suit against the drug maker. Im saving the pills to have them examined by a company who can provide a report on the ingredients as well as an attorney who specializes in this type of case.

REPLY

Was this helpful? 5

My small pharmacy switches tramadol brands often. Started Virtus three weeks ago. Now searching on the internet for my new problem; very soft stools began a week later. I have colonic inertia, so this is a problem for me. Pain relief is poor with Virtus. I have had BEST results with Caraco tramadol. I first got Caraco after three years, at different large pharmacy, with Zydus tramadol; first Rx, did not know there were other brands of tramadol. Took a lot of Zydus tramadol for fibromayalgia. I mean a lot! So Zydus did not work well for me, I found out later.

REPLY

Was this helpful? 5

I reported Amneal to the FDA maybe 2 years ago. I've never heard back from them. I have gone as far as going back to the original ultram by McNeil. Guess what. They don't work the same either. I BELIEVE THE ORIGINAL MANUFACTURER changed the formula. IMHO. They will not admit to it. I called them as well. My conditions for needing this script DOES NOT MATTER. What matters is the fact the they are playing with our lives...worse our sanity. They have bastardized our food supply and our meds. Is THIS population control? GMO's, antibiotics to animals, all of this is just making us sick making PHARMA more important. Take control of your life. Watch your food intake. Try meditation and soft yoga for pain. I'm going to. I AM GOING TO TAKE CONTROL OF MY HEALTH AND LIFE BACK. To Abigail and ALL others here, I FEEL YOUR PAIN. I'm suffering too. Health and healing to all!!!

REPLY

Was this helpful? 5

I have noticed an allergic reaction to the Mylan brand of Tramadol - itching and wheezing. Whereas with Teva brand I was ok. Anyone else or just me?

REPLY

Was this helpful? 4

Teva does not work for me. Does anyone know which major pharmacy carries Ultram or anything other than Teva?

REPLY

Was this helpful? 4

I learned how to take care of my life. I demand Caraco tramadol. It works for me. I started on Zydus three years ago, and took so many I thought that was how it was. I switched pharmacies, and first had Caraco brand. Then they gave be Amneal, and I was in trouble. Then I got Mylan. That did not work either. Then I got Caraco again, and learned that worked best for me. I also added 150 mg Lyrica five months ago, and for the first time in 15 years I can sleep long stretches at night. I have been on a gfcf diet for over three years, no four-legged animal meats, and do a care regimen that makes me feel powerful for longer stretches. I like your post in caps. We are.

REPLY

Was this helpful? 4

Twice now I have been switched from Mylan Tramadol to Amneal Tramadol. There is a big difference between the two. I have complete relief when I have Mylan but if it is Amneal I eventually get no reliefand have headaches, nausea, and pain. Have been on Ultram-Tramadol for years and have great results from it. Have a disease called Spondolytis and have been on methadone and everything else but Ultram-Tramadol has been the best solution. Have no side effects as long as I dont get Amneal Tramadol. I am also having the same problem trying to find Mylan Tramadol.

REPLY

Was this helpful? 3

Mylan works much better!

REPLY

Was this helpful? 3

I've been taking Zydus Tramodol 50mg for many years, just recent Walgreen's changed over to Mylan with is doing nothing for my pain,and making me sleepy and easily irratated. I called CVS and they carry Teva, I'm wondering if it will be the same as Zydus?

REPLY

Was this helpful? 3

YES. I totally agree. I got my prescription Wed of this week. By last night I was in so uch pain I couldnt lift my head, I was vomiting, blurred vision very angry and irritated so sleepy I couldn't keep my eyes open. I took a flexeril, and 1/2 gabitin and 2 benadryl. Thank GOD my husband takes the same med and he has some with the A on them not the M and I took 2, then fell asleep. I woke this morning exhausted and barely able to make it. But after 2 hours trying to wake up more of the A tramadol by 10am I was awake now it's 4pm had my doses can think straight again and feel like I was literally druged with poison. Mylan what the heck are you doing? Your going to kill people. How are you able to do this? How is this legal? How do the pharmacists not care and how do the Dr.'s not care? Why doesn't anyone care?

REPLY

Was this helpful? 3

is Tramadol hcl 50 mg mylan helping for Migraine Headache? ## It is a centrally acting analgesic, so it may help, some p...

8 REPLIES

one side of pill is a M and the other side of the pill is T7 ## what type of drug is tramadol hcl 50 mg. is it narcotic,...

152 REPLIES

I am looking to find out what is the difference between tramadol 100mg and tramacet. Are they both the same thing? The m...

19 REPLIES

I have had my C-6 and 7 fused years ago and had pain releif from that. My symptom prior to rupture was dull pain in left...

7 REPLIES

Which is better for pain? Tramadol, Hydrocodone apap 5 325, or Tylenol 3? I am on blood thinners ## Tramadol is stronger...

6 REPLIES

Has anyone been given Tramadol 50 mg manufactured by TRUPHARMA ? The table is oblong and has the numbers 018. Thanks ## ...

5 REPLIES

How many Tylenol 4 would I have to take to equal 400 Mgs of tramadol? I'm trying to keep the withdrawals at bay. Ple...

2 REPLIES

I took a Tramadol 50mg, at 6am how long should I wait before taking my Hydrocodone 10/325mg ## It's always best to f...

1 REPLY

I have been taking tramadol for about 8 years now. About 5 a day (50) mgs. Does anyone know if the withdrawals from tram...

17 REPLIES

What are the chemical make ups of Norco's vs the chemical make up of Tramadol. I know that Norco has Hydrocodone and...

2 REPLIES