Risks Versus Benefits Of Humira For Ibd Patients

Our son age 28 has sufffered from IBD most of his life. He has now been using Humira 40 mg every other week for over two months with no apparent benefit. In fact he gets worse after every injection. ( Fatigue, Malaise, Nausea, cramping, diarrhea, joint pains and RA type symptoms.) It seems that it gets worse with each injection. Labs no show that he has yet to reach therapeutic levels of Humira. Therefore the Dr has ordered an increase to once every week. He has great trepidation about follow this course. The questions are, How long should one reasonably have to wait to see some benefits. Do many patients have this level adverse reactions to Humira. We have been reading about deafness, migraines, and many other serious lang term effects. Anybody else out there with similar problems or insight? Thanks in advance

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Hello, Lyle! How is your son doing?

Those can be normal side effects of this medication, as reported by the FDA, and they have caused many people to stop using it, or to switch to alternative medications. So, I understand his trepidation, some of these medications can be very harsh.

As to how long, until he may see some benefits, there's really no way to say, it can vary from person to person.

Can anyone else that's been on this medication chime in with their experiences?

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Thanks for you response and kind input. The problem continued after each dose and so he DC'd Humira. Things aren't quite as bad now but are still very uncomfortable a good deal of the time. The biologics don't seem to help or treat him well. Indeed they are harsh and I strongly encourage anyone considering their usage to "do your homework!"

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