Rapid Weight Gain While On Allopurinol

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I started on allopurinol 100 mg tab in oct since then have gained 25lbs. Anyone else have this happen?

35 Replies (2 Pages)

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1

Hello, LaceyLu! How are you? I'm very sorry about the problem that you're having.

According to the FDA, Allopurinol is used to treat excess uric acid and it has been reported to cause rapid weight gain in a small percentage of people that take it. Other side effects may possibly include sore throat, nausea, dizziness, bruising and joint stiffness.

Have you spoken to your doctor? It might not be the right medication for you to take.

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2

I am on 200 mg a day, I didn't notice until I saw your post, but I have gained 50# in 2 years. I thought I was overeating but I actually eat weather and don't hardly ever eat junk or fast food. I will definitely be bringing this up with my rheumatologist. Ty

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3

Hi, Thanks for the reply, I started researching the weight gain and read 25 % of people on Allopurinol have a rapid wgt gain. I noticed being really hungry like when taking steroids.

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4

I have been on Allopurinol for 2 months and have put on 3kg. Am exercising more than before and eating the same.

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5

I am 60yrs old take 200 mg allopurinol each morning for past two years and have gone from 185 to 203 lbs basically eating the same - if not less because I don't like the weight gain - same amount of exercise - maybe even more walking. What is it about Allopurinol that causes this - is it dangerous - and what do they recommend? Can't find any info online and doctors have no solution. I believe I would have to be on an extremely low calorie diet to lose the weight.

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6

This medication should be remove off from Distributing because it making people obesity and I can prove it! If take 100mg you will gain25 pounds, if you take 200mg you will gain 50 pound, if you take 300mg you will gain 75pounds. Please take it off the market I'm one the person that have gain a lot of weight taking this medicine!!!!!ASAP

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7

This medication should be remove off from Distributing because it making people obesity and I can prove it! If take 100mg you will gain25 pounds, if you take 200mg you will gain 50 pound, if you take 300mg you will gain 75pounds. Please take it off the market I'm one the person that have gain a lot of weight taking this medicine!!!!!ASAP! I put on 79 pounds since I've been taking this medication.

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8

Are there other scripts other than
Allopurinol to avoid weight gain?

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9

Are there any other gout medication rather than Allopur 100mg to avoid weight gain

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10

I can attest to the weight gain from allopurinol...I've been taking it since March, 100mg.
I've gained almost 15 lbs. My clothes are getting so tight, it's uncomfortable...What can I do?

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11

Hi Lacey, I feel the same. I've put same on and eating healthier and exercising more but doctors don't seem to agree.

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12

I am on 300mg and my weight has gone up to just over a stone , I do weight watchers and I am really getting fed up with this weight gain

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13

I am on 300mg allopurinol and my weight has gone up to just over a stone , I do weight watchers and I am really getting fed up with this weight gain

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14

Thank you I couldn't figure out what was wrong with me I am on 400 mg of allopurinol day I exercise eat my ass and I foot on 17 pounds in the last month making an appointment with the doctor tomorrow thank you

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15

I've stopped taking allopurinol for a week and lost 6lb. Gonna see how I get on next week then call doctors.

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16

OMG! I TAKE 300MG FOR LAST 6YRS.. STOPPED FOR 2 WEEKS AND LOST 15#

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17

I been taking 300mg Allopurinol for a little over a year and have gained 25 pounds. Very depressing :(

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18

Re: Nancy (# 17) Expand Referenced Message

I stopped taking it and have lost 7 lbs in the last three weeks without changing my diet. You try to cure one problem and it gives you another problem! I wonder what Chinese Herbalists would do for Gout??

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19

I started taking this about 18 months ago and have gained 80 pounds. I am now having problems with blood pressure, edema, and almost daily headaches. I kept telling my dr that I'm eating better (1k calories a day) and exercising more but still gaining weight. I started taking phentermine and STILL gained weight (in the past I could drop 10 pounds very easily in 2 weeks while taking it) and tried Truvision too. I had my thyroid checked along with lots of other things. The pharmacy was closed and I didn't get my allopurinol filled.... in 2 days I lost 4 pounds. I have started a chart to make sure that is the source but regardless I was still been getting kidney stones even while taking the meds.

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20

Yes on allopurinol i am rapidly gaining weigh
and when I am on febuxstat weight stays static , no gain no loss.

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35

Re: Allen G (# 32) Expand Referenced Message

Sounds about right! ALL of those symptoms Ive encountered since taking it.

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34

Yes I've been on it about 3or4months and gained about 50pounds and it keeps going up every day I just cought on to it cause it came on so fast I have to call my Dr tomorrow about it

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33

I dropped 10lbs as soon as i got off of it. as for the GOUT, I found a Doctor who told me to STOP with anything tht had Fructose it in. Sodas, sweets, Fruit juices and ALL alcohol. Also cut out the Grainy foods. THis will cut the inflammation response down in out bodies dramatically. THIS works! im back to eating some meat and I have not had a full blown attack in a year and Im almost completely off of ANY type of Gout MEds.

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32

I have been on 100mg of allopurinol for about 3 months and gain 35lbs. My VA doctor this is normal reaction. I don't want to gain weight. Would anyone know an alternative? I never had issues with gout until the VA put be on 12 100mg tablets of prednisone for tendinitis. I been having sleeping issues, headacks, weight gain, memory loss, and major digestive issues.

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31

Re: epsavoy (# 30) Expand Referenced Message

I been taking 300 mg a day for several years. But this last week I literally gained a pound a day. Thanks for the info.

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30

I started taking allopurinol a month ago and have gained 12 lbs eating less and exercising more! This is ridiculous! I thought it was just me until I saw this thread. Thank you for this info. Now I know Im not going crazy

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29

Re: Donna (# 26) Expand Referenced Message

I am having the same problem.. Have you been able to try anything else?

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28

Yes... I am on 400mg of Allopurinol. I have been on for 30-45 days! I have put on over 15lbs! In addition, I have still had at least 2 flareups during that same period... There is DEFINITELY a correlation between Allopurinol and weight gain!

FYI: there are some new clinic programs out there; however, they are extremely expensive and most insurance doesn't pay! I was fortunate and may be accepted to a trial program! It gets rid of GOUT in seven months!

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27

Went shopping today, had to buy a size L shirt. Was a small and only last year started buying medium. Belly seems to be growing daily since I started taking allopurinol.

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26

I too have gained a lot of weight since being on this medication. I wasn't sure what was causing me to gain so fast especially when I'm trying so hard to lose weight. ugh...really depressing.

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