Promethazine W/ Codeine And Suboxone

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Shelly girl Says:
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I need help please. Severe pneumonia and cough. Can you take Suboxone with (Promethazine + Codeine)? Please I need relief fast, I'm so miserable. Thank you so much.



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Roy Says:

Hi Shelly girl, the short answer is that No, you cannot take those together.

Codeine, being an opiate, would pose a drug interaction with both the Buprenorphine AND Naloxone contained in Suboxone.

Codeine w/ Buprenorphine could amplify central nervous system depression, leading to respiratory distress or even coma in extreme cases.

Codeine w/ Naloxone can counteract each other causing withdrawal symptoms (nausea, vomiting, aches, fever, etc).

Promethazine also interacts with Buprenorphine, and can increase certain side effects such as dizziness, confusion, drowsiness, etc. [1]

That being said, I'd avoid taking them together unless your doctor has specifically cleared you to do so and knows your exact dosage amounts.

PS - Sorry to hear that you're feeling sick! Are you on antibiotics or anything else for the pneumonia? Best wishes and hope you feel better!

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