Paxil & Trazodone Together?

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Sandie Says:
I have been on Paxil for anxiety for about 6 months, I was having trouble sleeping so my Dr added Trazodone 50mg 1 an hour before bedtime. Just wondering if anyone has been on the two together, and is it safe, since Traodone is also an antidepressant, I have to say I actually feel even better now, than when I was just taking the Paxil. I have been taking the Trazodone for about a month now.

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David Says:
Hi Sandie,

Hopefully your doctor was aware of this before adding the Trazodone, but according to various drug interaction checkers, combining these two medications may increase your risk of developing a rare but serious condition called serotonin syndrome. Symptoms associated with serotonin syndrome that you may want to watch out for, can include the following: Confusion, hallucination, blurred vision, seizure, extreme changes in blood pressure, increased heart rate, excessive sweating, fever, shivering or shaking, muscle spasm or stiffness, tremor, incoordination, stomach cramp, diarrhea, nausea, and vomiting.

In my honest opinion this combination isn't safe unless your doctor set up an appropriate dosing schedule for each medication to be used in adjunctive therapy with one another.

I hope this helps!

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Janet Says:
I have taken Paxil 30 mg for years for anxiety . Dr. has taken me off Temazepan 15 Mg which I use occasionally. And wants me to take 50 Mg Trazodone for sleep. Which I do not need all the time. I do take coumidin. Is this OK??

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Ceecee Says:
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I have ME/CFS/Fibro....Watch your weight with trazadone. I have had success with sublingual 5htp for sleep. Regular 5htp during the day for anxiety along with theanine (FYI, watch the b6 in 5htp products or sny nutrients. I became toxic on b6. It causes numbness in feet. It is the only b vitamin that builds up in people and can cause permanent damage)
I stay away from ALL anti-anx. meds. I've experienced dementia type side effect even on benadryl...the diphenahydramine ( which is in many products even cough meds) is anti-cholinergeric. Be careful and Happy Healing.

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Michelle Says:
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For some reason Dr. All of a sudden took away the Paxil because I was taking trazadone as well. I wasn't given a reason why but if I took the Paxil then I had to return the trazadone??

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