New Opioids Coming Soon

Updated

So I've been doing some research and came across these new drugs out now or coming soon. Just wanted anyone's opinion on them. Or if you have tried them, what do you think?

1: Vantrela ER (Hydrocodone Bitartrate)
2: Arymo ER (Morphine Sulfate)
3: Probuphine (rod-shaped subdermal implant that last for up to 6 months & costs anywhere from 1,700-5,000 bucks for six months worth)
4: Belbuca (Buprenorphine) doses run from 75-900 and costs run from 250-700 bucks

There's one more but it does not have a name yet. It's just called NKTR-181. So if anyone has any info on these please share your thoughts and or if you tried any of them please let me know how they worked or didn't work. Or if I left some out or you heard of other ones I didn't mention please feel free to update me.

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Yes, I've tried the hydrocodone/bitartrate. For me, the only good thing is it protects the liver. It does nothing for pain and I mean nothing!! I've had to take 3 at a time and that doesn't help. So I don't care for this opioid at all.

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Re: Drakee (# 1) Expand Referenced Message

This is EXACTLY what the politicians and others that have no concept of pain want. A so called "opioid" that has no effect on the consumers of these "meds". They think that by manufacturing an "opioid" that has no effect on people (and thus no effect on pain) will cause the long term chronic pain people to not be addicted to their pain meds. If you take any of these so called "opioids" you may as well be taking straight tylenol or advil from an over the counter source. The main difference being that a Doctor can prescribe these so called "pain meds" and over the counter pills like tylenol and advil cost whatever is charged for them and will not be reimbursed by your insurance. This is the world we now live in. People with long term chronic pain are being grouped into the group with illegal drug users and street level addicts. These new "formulations" are a scam and absolutely worthless.

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Re: Drakee (# 1) Expand Referenced Message

Was it Vantrela though or was it a generic? If so, what was it called? Was it expensive? And I believe you when you say it did absolutely nothing for your pain! What did you switch to? And have you heard of any of the other ones I mentioned? I currently take oxymorphone 30mg ER and oxycodone 30mg IT. Both are great.

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Re: w john (# 2) Expand Referenced Message

Exactly,, you nailed it. I can't believe that they are getting away with this , pain dr.s / clinics are closing doors, don't want to deal with treating chronic pain,, if you are lucky enough to have superior insurance or are on the ellete side of life,, maybe your name appears in the stars or you throw an awesome football ,,,, for those people, the good stuff,otherwise forget it, you and your quality of life do not matter ,, this new government issued pill is all you are going to get, so get used to it,, America the great !!

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Re: Big red balloon (# 4) Expand Referenced Message

God forbid that you should even make an attempt to discuss your situation with your Doctor. No matter how humble you are. No matter how reasonable you speak ANYONE (with a few rare exceptions) that broaches the subject of pain medication is considered a "chaser" or worse. This is another fine example of the government rearing its ugly head and thinking that they can eradicate a so called "problem" with their government interference. Drug abuse IS a problem but denying people with REAL problems their medication is just throwing the baby out with the bath water. Why should law abiding people with real conditions have to pay the price for criminals who abuse the system and steal the pills from the ones that are prescribed the medication? Worse yet, why are honest people grouped in with street addicts and heroin users? I have written to every Congressman/Representative that I can think of and I have never gotten so much as the courtesy of a response. I guess that these Representatives think that responding to (what they consider) a dope fiend is just a waste of their time.

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Re: Big red balloon (# 4) Expand Referenced Message

Yea I've been hearing a lot about how all these pain meds are being tampered with to the point where people are going into FULL withdraws taking their normal dose n even after tripling their dose they get no relief. And forget about ALL the new meds ALL of them are straight GARBAGE!!! That's part of the reason starting this thread is to show how all the stuff is WATERED DOWN!! To the point of the meds not working. That's BIG Pharma and the Government are gonna deal with this so called epidemic. I'm just lucky they haven't gotten to my meds yet believe me it's coming n the day it does is gonna push me over the edge and force me to g0 down a path I don't want to go!!! Luckily I have GREAT insurance,Great PM DOC and a great staff at my Pharmacy that know me for 2 plus years of being a model customer never trying to fill early or cause a problem. They somehow found out about a survey I took and gave them RAVE reviews they love me even more now and I've never had to wait for my meds to be ordered they ALWAYS just have them in stock for me. Can't ask for anything better but I'm one of the few who can say this n I'm glad I am cause I've been to a few places where I've been treated like a piece of sh#t n trust me that was no way to live not knowing if I was gonna be able to fill or not glad that's all in the past.

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Re: w john (# 5) Expand Referenced Message


When I signed my opioid agreement, 8 years ago, they asked, please be honest with us. I have abided. I would almost think that pm. has violated their own rules, lying. Lying about the integrity of the pain pill that now has been stepped on with an opioid binder that cancels out the effects of the drug. Thank you pain management for knowing that the government wants to shove poison down our throats and turn our lives into throbbing stabbing pounding exsplosive hell. How stupid do they think we are! So it's ok for them to lie, hmmmmm. I need to rethink if I want to be honest with that opioid agreement, maybe even climb over walls to find honest real relief. From all of the posts that I have been reading, it seems that our voices are not being heard. We can all get together and discuss the wrongs, support each other with a pat on the back and listen, but in the end if our voices cannot change this wrong, really, what or whom will. :( Apparently they didn't get the memo that chronic pain is real. Tell your patients that it's all in their heads, lol poison in your pain med, nobody else thinks so. :) good day.

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Re: w john (# 5) Expand Referenced Message

I know I have been on the same med for a very long time never had one issue and now the insurance company won't pay for one of my prescriptions because it's oxycodone so now they have to cut that one in half. I need it for the pain it's getting harder and harder for those of us who truly need it.

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Re: w john (# 5) Expand Referenced Message

I read on february 10th that the dems got the rep to put in a billion to help addicts. You know someone is going to steal that money, and these script writers are taking away my muscle relaxant, which is a non-narctic. I got so upset, ended up in a lot of pain I haven't had in years. Told I was going through withdrawal. They're just ripping off insurance companies. I've been bedridden till I find another doctor. Good luck to all my people in pain.

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None of these drugs are actually new. They are the same as other medications already on the market. These are just made by different manufacturers than the other ones.

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Re: w john (# 2) Expand Referenced Message

U are so right, I've been given some of these fake or at the very least, defective brands of norco, & I am a REAL pain sufferer. This bull**** isn't right, the government & FDA is playing dangerous games with real pain patients. I've suffered SEVERE HEADACHES from 2 different brands so far. I guess I gotta SUFFER ANOTHER MONTH & even then, hope for the best with another generic. I can't seem to get a good, straight answer on this site, as far as what seems to be the "best" ones out there lately regarding the 10-325 dose. Any thoughts?

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Re: Rawdog (# 3) Expand Referenced Message

I've been asking my primary physician to change my script and he says Norco 10/325 is the highest he can give me. I just don't believe that. I don't know what to do. Pls help!!

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Re: Drakee (# 12) Expand Referenced Message

It probably is the highest he can give you without switching to Pain Management. Your average physician can usually only go that high with out worrying about getting looked at by the DEA or getting his licence taken. That's what it's come to for some 7yrs plus now. Y0ur actually lucky to be getting that.

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Re: Drakee (# 12) Expand Referenced Message

Any doctor can prescribe any opiate he or she believes a patient needs. Unfortunately, many doctors lie to their patients and tell them they cannot prescribe. Instead of telling them they chose not to,

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Re: BL (# 14) Expand Referenced Message

While your right that any doctor can prescribe what HIS patients need to take, you'll never see a regular one just up and write for Roxicodone or Methadone or Fentanyl cause like I said before he does not want to risk his job or have the DEA snooping around wherever you would try and fill at. They would definitely see that it's out of the ordinary that this doc who never writes for something that strong all of a sudden is. It's just not worth it to him to do so. Hope that clears things up.

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Re: Rawdog (# 15) Expand Referenced Message

Doctors need to be able to justify what they are writing and for what. NORMALLY, the lowest pain med is prescribed and then a step therapy is employed. If the lowest pain med does not offer any relief then a Doctor moves it up a step at a time until they reach their (the Doctor's) comfort level. They then refer the patient to a pain management clinic. This can be a kiss of death as pain management clinics are really attuned to finding and weeding out the scammers and it takes forever to establish a relationship with a new Doctor. This area is one area where you are truly "guilty until proven innocent". A proven history of pain does not automatically make you eligible for stronger pain meds.

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Re: Rawdog (# 15) Expand Referenced Message

As I said, the doctor has to be comfortable with what he prescribes. No doctor is going to prescribe stronger medications first. It does not matter if they are a PCP or a Pain Management Doctor.

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I tried belbuca when the FDA pushed Opana off the market. It's very expensive and not covered by my insurance which is a very good policy. Slightly effective at high dosages but now I'm on oxymorphone from Impax and it is not covered by insurance either although not quite as expensive as belbuca.

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Re: Lynn Pain (# 11) Expand Referenced Message

Sorry to hear your experience. Unfortunately there is no consensus on which manufacturer makes the most consistent generic pain meds. I have read from MOST that the "Actavis" brand is truly awful. From personal experience I agree. "Actavis" was bought out by the "Watson" company back in 2014. (All of this can be confirmed on the internet) The new company has reformulated their generic hydrocodone and what they have done is awful. For example, if your doctor was to write a prescription for 7.5/325 hydrocodone BY LAW it is okay if they only put in 6.0 of the hydrocodone and NOT the 7.5 milligrams that your prescription is written for. PLUS the "binders" have been reformulated and are of the lowest, most awful quality that they can get away with putting in their pills. I changed pharmacies and they deliver another brand that is barely okay. I talked to two pharmacists about how the quality has fallen way off and they both said that they are getting complaints daily about the quality as well as the complaints that are going into the Corporate Office's of both companies. I was advised by BOTH pharmacists that if I want consistent quality that I will need to go to the name brand of the hydrocodone I am prescribed. For example, fill the script with "Vicodin" (YES, it is still being made) instead of generic hydrocodone. I am trying to get my insurance to cover this but it is quite a fight. I was denied pending a more elaborate history of WHY I am asking for the name brand instead of the generic. I would love to relate to everyone what my insurance has put me through so far but it would make my post too long so I'll refrain. I wish there was a magic "pill" that everyone could be referred to but in today's political climate passion has overtaken reality and EVERY user, legal or not, of pain meds is being rolled up into the same group with street heroin users and criminals that steal their pills from friends and family members. It is so ridiculous that the Doctors have to be put through what they are being put through.

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Rawdog--

I enjoy and appreciate your comments and feedback. My experience (which mainly includes doing research on the subject) makes me believe that these "new" pain meds are just reformulated meds that are designed to take out the things in pain medication that creates a euphoric feeling. The idea being that if there is no perceived "high" that people will not want them. The problem with this approach is that (depending on whose opinion you believe) when you try and reformulate the medications to remove the euphoric feeling that you also remove the painkilling properties of the pain meds leaving you with a "pain" med that is no more effective than a tylenol or advil. The manufacturers are being forced to bow down to the political climate and the frivolous lawsuits that cost them millions. When a manufacturer is sued by a non-profit and they win they are often awarded attorneys fees which the non-profit never pays. The so-called non-profit just is dissolved or goes bankrupt leaving the manufacturer with millions in attorneys fees that they just have to eat. There is also the problem of States Attorney General's suing with their bottomless pit of taxpayer money to spend. Some of these manufacturers have actually had a case dismissed in the first level of Court but they just file frivolous appeal after frivolous appeal because, after all, they are not having to pay for it the taxpayers are. This leaves REAL, HONEST pain medication patients left with pain medications that are, for all intents and purpose, worthless. No "new" pain medications are, in this political climate, ever going to be effective because they have been re-engineered to be ineffective.

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What pain medication is in an oblong tablet imprinted with 109 and 500? Is that Vicodin or Naproxen?

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Re: Keeping it real (# 22) Expand Referenced Message

If a doctor writes prescriptions for Schedule III drugs. He can also write prescriptions for Schedule II drugs. By the way all drugs containing Hydrocodone have been Schedule II since October 2014. Your doctor lied to you.

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Re: Drakee (# 12) Expand Referenced Message

Also some doctors do not want a schedule 2 license to write schedule 2 drugs like Percocet, morphine, any type of oxy’s. I had a dr that didn’t renew his schedule 2 license; he only writes schedule 3 down, like norco, Lortab or you know anything with hydrocodone, Tylenol 3 or any of the other schedule 3 drugs. It’s a terrible shame people have to suffer at all due to this dam government bulls***. The doctor I was referring to was years ago, now you couldn’t get Motrin here without a lecture. The state of North Carolina has been shut down, doctors are terrified!!!! I had a doctor tell me that he is so tired of losing sleep cause all he does is worry about the government's strict rules and he’s afraid just one mistake is all it takes and boom license gone and no more practice. Many, many doctors here have been shut down & offices cleaned out. I tell ya, I say it’s a criminal act to be done this way. If you are following the rules even with pill counts, checking drug levels or whatever and you are still kicked to the curb to me it’s just down right unethical......

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Re: BL (# 14) Expand Referenced Message

Now when I get my Norco 10/325, it's got bitatrate!! Not good. It takes a long time to work....3-4 works. But they go very fast. I'm tired of being in pain. Just tired...

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