Naltrexone And Kratom

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Redhead Says:
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I've been taking approximately 6g of kratom every 4 to 6 hours for about 2 years now. I want to use a weight loss medication which contains naltrexone but wonder if it will cause withdrawal sickness because of my kratom use?



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Jojo Says:
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Hi, I am in the same boat as you. Have not been using Kratom that long (about 6 months) but want to start Contrave for weight loss. I am also hoping the naltrexone will help me not use the Kratom anymore as I have been trying (unsuccessfully) to quit for a few weeks now. I think it will help with that but my concern now is that I will go into extreme withdrawals when I take the first dose. Did you end up taking yours?

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David Says:

Personally, I think it would be best to consult a doctor for the purpose of setting up a tapering schedule with kratom in order to lessen any risk of a possible drug interaction during the transition to Naltrexone.

I was researching kratom's half life just to try and get a ball park figure of its excretion rate, but apparently kratom's half life differs depending on which strain of kratom you take. For example: Green vein strains reportedly have the longest half life of about 8 hours, whilst Red vein strains are said to last an estimated 4.5 to 6 hours and White vein strains around 4 hours.

Other characteristic traits of kratom that allegedly affect half life (and how long it may take to leave your body) may also be determined by their alkaloid profile and leaf density.

Having said this, I feel that a lab analysis of your specific kratom strain/variation is pertinent to receiving the most accurate answer on half life.

However, the doctor who is prescribing you Naltrexone should still be able to help you taper off kratom (more easily) to avoid serious withdrawals, provided that they have an understanding of kratom's duration of effect.

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Jojo Says:
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I replied earlier saying that I was in your same boat. I ended up taking my first dose of the Contrave the next day (had not used Kratom in about 24 hours prior to my first dose.) I did get very nauseous and vomited both the first day I took the medicine and the second. Many people report this as side effects in the beginning so I don't think it had anything to do with Kratom withdrawals. Your Kratom usage and dosage was longer and higher than mine so YMMV.

By the way, I have been on the medication for a week now and the side effects are no longer present.

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Sage Says:

YES IT ABSOLUTELY WILL CAUSE HORRIBLE WITHDRAWALS!!!! I experienced this first hand last summer trying to stupidly rapidly detox myself from kratom at home. I only took half of a naltrexone and it threw me into some of the worst withdrawals I have ever had that lasted for DAYS. I wanted to die. I could barely move from my bed to the bathroom. Horrible diarrhea. No sleep for three days. Intense opiate withdrawal symptoms (skin crawling, sweating, chills, nausea). Please don't do it. You will regret it. That was one of the dumbest things I ever did.

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confusedpatient Says:
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Would this be the same going from Kratom to a low dose Butrans patch?

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sctshgal Says:
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I took my first dose of Contrave this morning and my dose of Kratom also. OMG don't do it! I am having horrible withdrawals, Sweaty and chills at the same time, I feel absolutely awful!!! I am wondering when it will end. I will not take that again!!

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Abby Says:
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Omg, I just did the same thing as you--use kratom daily and started 1 dose of contrave. I went into horrible withdrawals and went to the ER last night. I tried to explain that the 2 drugs interacted badly, but unfortunately since kratom isn't fda approved the doctors had no idea what was going on. Anyway no one should ever start contrave with kratom still in their system unleass you want to feel like you're dying.

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Lisa Says:

I am currently taking naltraxone so I could stop taking Kratom. I was heavily addicted to Kratom for over 2 years. I have 5 months clean today and considering quitting naltraxone. Kratom will have no effect while taking Naltraxone.

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Jack Says:
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How long after getting vivitrol can you feel the effects of Kratom??

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Krysb Says:
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If you take Kratom, DO NOT take contrave at the same time. Especially if you have been taking Kratom for an extended amount of time. I have been on Kratom daily (heavily) and tried contrave for the first time yesterday. I am just NOW feeling halfway normal. Within an hour of taking the pills, I had full blown withdrawals that made me feel like I was dying. DONT DO IT!!!

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DefinitelyGlen5 Says:
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Re: Lisa (# 8)

How are you sure Kratom has no effect? Do you have a study to cite? I have been searching for something concrete not so anecdotal or subjective

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Lady1 Says:

Don’t take Contrave if you have been taking Kratom. I would recommend coming off Kratom and being 2 weeks without it before taking Contrave. It will put you into withdrawals (bad withdrawals) within one hour of taking the first pill. I don’t know what I was thinking, but I just spent the last 24 hours in hell.

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Tori Says:
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Re: Abby (# 7)

Did they do anything for you at the hospital? My fiancé took one of my contrave thinking they were headache meds, took his Kratom and is going through horrible “withdrawal” like symptoms but he says a million times worse than he’s experienced.

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