Mylan Ms Contin

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Bob Says:


My pharmacy was out of my regular brand ms contin, I had to wait a few days (they suddenly didn't have the medication I got there for over 10 years. seems strange to me.

A day or two after I started taking these, my leg pain came back, I have burning pain all the time, with my regular brand ( I think they are by Purdue) small darker blue pills, I never had pain even if I overworked my leg.

These new ones are larger and made by mylan, they seem to work ok in the morning, but the pain gets worse when I usually do things in the afternoon.

The others stay with me all day, I start to get pain late in the evening a few hours before my next pill is due.

I have learned to live with the others,got things I needed to be done, with these I can see me becoming a couch potato.

Has anyone experienced anything like this, tomorrow I'm going to the pharmacy,( rite aid) , and give them back they are useless.



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Conor McEntee Says:

I have been on ms contin for six years. I just got the new mylan ms contin 30 mg a few days ago. I hate them.! They don't work very well at pain relief like the old small 30mg ms contins. I will make sure I never get these Mylan ones again.!!

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Bob Says:

I am a disabled veteran with a spine injury. The VA pharmacy changed the manufacturers brand from what I usually received from them to Mylan MS60's and I got sick with the classic opiate withdrawl symtoms and little pain relief. I have had to endure the weekend without proper pain management. Not sure if I will be able to have this issue corrected. The ingredients in the pill changed and I think I have had a reaction to ingesting these different substances. Also the pills are enormous. I have had problems with swallowing large pills and have notified my doctor regarding these issues in the past. I also have had severe constipation problems and I believe the larger pills will also increase this problem. It is unfortunate for me as my doctor and I had made great strides by adjusting my medicine to correct the constipation issues. How are they allowed to do this without the doctors or my prior knowledge? It's like the pharmacists have the power to override my doctors prescribed treatment without regard to my medical conditions.

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Bob Says:

I was on the Mylan 15's, I was taking them at first like I took my old small 15's for about 2 weeks.

The druggist suggested I take them at different intervals, that didn't work either.

I went back to my doctor and he gave me another perscription which I took to a different drug store that carried my old brand (Mallinckrodt).

I went back on the old brand but now my old brand doesn't seem to be working as well as it did, to get pain relief I need to take an extra 15 in the am where as before the 3, 15's carried me thru the whole day.

What do I do now, I don't have an endless supply of extras, the extras I have are from what I saved over all the years I have been on Ms Contin, when I was tapering down as I could stand it.

I think I need to go see my pain specialist again, I was so well adjusted I only had to see him once or twice a year.


I seriously think this junk disrupted my system making my old reliable brand less effective.

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Suzanne Says:

You are so right! I took the small ones for years with good results. These new big ones are doing nothing for my pain.

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Bob Says:

I had to switch drug stores to get the same brand I was taking before.

Just recently I was given the large ones again, I promptly took them back and told them I do not want or ever want to take anything made by Mylan.

BTW Mylan sent me a letter telling me after checking they could not determine that anything was wrong with my meds.

I wonder how they did this checking, they never got any of the pills off me to test so how do they know they are OK. sounds like BS to me.

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Conisuwer Says:
via mobile

I just got the new mylan ms contins I think they work great I take 1hundred mg every 12 hours with these I took both at the same time I was feeling good from 11am till 3am I think they are way better than all the other brands I tried

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Chris Says:

I have been taking MS Contin for yrs for a spinal cord tumor. Only reaction has been constipation. New form manufactured by Mylan has caused multiple side effects, upset stomach, dizziness, heart palpitations as well as diff swallowing such a large pill. Pharmacy states nothing can do. Scared to take due to severity of side effects.

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Susan Says:

I have the same problem. I just called Walgreens where I always have my prescription filled. I had the small pill and then 2 months ago they changed to the larger Mylan pill. The smaller pill was a different manufacturer. I told her the Mylan, larger pill must have a filler in it or something because the time release did seem right. It's not working for the pain like the smaller pill from the other manufacturer. She did say I was the first to complain.

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9
spanky Says:

I too took the new Mylan MS Contin...I felt flushed....sick to my stomach....and dizzy...within 30 minutes of ingesting. I fill mine also at Walgreens...Bad stuff....Ive asked to get my old brand back Malincrodt (SP)

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Susan Says:

Spanky, I went and had my prescription filled at CVS, it was worth a try- they had the small ones that Walgreens had before. Finally, after suffering 2 months with the Mylan, I'm back on what I had before. Check with your nearest CVS. Looks like Walgreens is trying to save money using the Mylan product. The Mylan pill is twice the size. I wonder if they are putting a filler or something in it and that's why it doesn't work properly. I could not get an answer as to why the pill is larger only that it was supposed to be the same ingredients. If they are using a filler, asprin or something else, people might be allergic to. It doesn't see right that a pharmacy can change what a doctor supplies. It was my oncology nurse that explained to me that different manufacturers produce the same drug, but that it can be off 20% as to how it works.

I ask myself, Why isn't the FDA or someone looking at this issue? Also, I'm one to question, think of the elderly (I'm 61) that has no one to help explain and they take what's given to them.

Good luck everyone,
Susan


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terry Says:

i was doing great with ms cotin for my chronic pain. i am allergic to most meds. i got the mylan brand and felt so sick and did nothing for my pain. i been in bed for a month now. i called my mail order co. from my husband job and they can get me the mallinckrodt brand. i hope it comes soon. why doesnt the fda leave enough alone. i am sure mylan is a lot cheaper.

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Susan Says:

I had the same problem, you will see my post below from March 11th. I switched my pharmacy from Walgreens to CVS. That's what you should do - here's what I posted in March.

Spanky, I went and had my prescription filled at CVS, it was worth a try- they had the small ones that Walgreens had before. Finally, after suffering 2 months with the Mylan, I'm back on what I had before. Check with your nearest CVS. Looks like Walgreens is trying to save money using the Mylan product. The Mylan pill is twice the size. I wonder if they are putting a filler or something in it and that's why it doesn't work properly. I could not get an answer as to why the pill is larger only that it was supposed to be the same ingredients. If they are using a filler, asprin or something else, people might be allergic to. It doesn't see right that a pharmacy can change what a doctor supplies. It was my oncology nurse that explained to me that different manufacturers produce the same drug, but that it can be off 20% as to how it works.


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Jen Says:

I have been on MS-Contin 15mg pills for a couple months now for various chronic pain conditions (degenerative disc disease, osteoarthritis of the spine, the bladder disease interstitial cystitis, and fibromyalgia). The first 2 months I had the small blue ones from Mallinckrodt and I thought they were awful - they barely touched the pain. This month, I ended up with the larger blue Mylan ones and it's a big difference - for me, they work BETTER. I think it just depends on individual body chemistry. To be honest, oral morphine isn't particularly effective no matter how you take it, as its oral bioavailability is only about 30% (for oxycodone, oral BA is about 95%), but I'm sure various people respond to the different formulations differently….

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eric Says:

I have received mylan ms contin they aren't effective at all

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Susan Says:

Bob, please see my comment below from Mon, May 05 '14:

Walgreens switched their vendor so they no longer carried the original brand of ms sulfate I was taking that worked! After doing some research, I called CVS to make sure they carried a different brand, which they did. Mine are a small pink/purple pill that works correctly. It's time released, which is great and does it properly. The Mylan brand from CVS is larger, but doesn't seems to time release properly, helped with the pain a little at times. I think it's filled with filler and who knows what that might be? The FDA should investigate this. I'm 62, have internet access and was able to solve the issue by changing where I got my prescription filled.

Think of the pour souls, elderly people that don't know that they can get the proper brand by having it filled at a pharmacy that has the correct brand that works.

It seems to me that Walgreen's may be trying to save money by using this other generic brand. They told me no one else complained - I can't believe that. Look at the complaints here. There's probably many more, but people taking this type of medication are older and may not have access to the internet as we are so fortunate to.

I suggest you have your prescription filled at another pharmacy. Call them first and be sure to find out who the manufacturer is. I was lucky enough to have had one of the small pills was taking so that I could research who the manufacturer is. If you don't have that, you can search on the internet and look for the pill you were taking.

I hope this helps you and others that are going through this issue.

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Torn Discs Says:
via mobile

I was switched to this brand MsContin 60mg after being on OxyContin 60mg for 2.5 yrs. (tolerance is a b****!) I told my Dr that I should of been given the 100mg x3 daily, but he felt that since I never have taken any of the morphine type pain meds, that 60mg 3x daily would be enough..... F*** Noooooo..... MsContin at any dose sucks Big Time for relieving pain!! Oxycontin is 100x more effective at blocking pain than MSContin.........

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Torn Discs Says:
via mobile

Yeah the Mylan ER isnt bad, just have to get use to them, as with every medicine that might have slightly different release points.

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Torn Discs Says:
via mobile

Oral oxycontin (perdue brand) has a 60-86% bioavailability.....
Oxycodone IR(genaric)has a BA of 40-60%
Morphine Sulfate has a 20-25% BA in all forms (ER and IR).


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rue Says:

I agree. The big Ms continue does not work. I think they are getting them tron Mexico. ???

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MaryJane4Pain Says:

There were originally 5 plants that manufactured MS Contin. There are now two. The larger pills have more filler in them as a deterrent to people who misuse the medication. This makes it much more difficult for addicts, but once again, the people who really need the medication are the ones who suffer. I had to come off of a medication that worked fine for pain relief because my kidneys could not process the fillers in the medicine.

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