Methotrexate Side Effects

4 Replies Updated

Conversation Starter

Tiddly Grace Says:

I have been on Methotrexate and folic acid for 3 weeks. Started with three 2.5 mg tablets of MTX for two weeks, then up to 6 tablets this week. The first week, I had terrible stomach pains, the second week I had bad fatigue. After taking my 6 pills on Friday, the side effects have been bad: nausea, no vomiting, diarrhea, stomach pain, back and right side pain and a rash. I finally reached the doctor on call in my practice (Memorial Day), and his comment was that it didn't look like I could take 6. My question is this, if you have switched to the injectable MTX, did you have less side effects, and at what point in your treatment did you switch?

Showing Replies 1 - 4 of 4 RSS Feed

Page of 1     Sorted By:
Renee Says:

Hi my son started taking the injection 3 weeks ago he have had some stomach pain but no nausea. His doc told me pills have way more side effects than the injection. Hope this helps

Was this helpful?     1     0  
David Says:

I just wanted to comment on the statement from that doctor who said that pills have way more side effects than inj's. I actually strongly agree with this notion because pills are usually comprised of a variety of binders and fillers that also make up a tablet's composition to help add bulk. My feelings are that these "inactive" ingredients are more harmful than they are beneficial, since most of them aren't recognized as having any real medicinal value, and in my own observations may even inhibit bioavailbility to an extent. On the other hand, a simple inj. is mainly composed of the active ingredient and perhaps sterile liquid or something fluid as opposed to solids, which wouldn't "get in the way of" the substance working as well as it is intended to. So looking at the bigger picture it would seem to me that inj's. are more straight forward, if you will, when it comes to administering the medication without all the "extra" ingredients that aren't deemed medically necessary.

Was this helpful?     2     0  
Tiddly Grace Says:

I stopped the methotrexate and went on 10 mg. of Arava for 1 month with no major side effects, but no change in level of pain. Then moved up to 20 mg of Arava with bad side effects and no relief. After dr. visit today, as soon as it insurance approves it and my blood work is ok, I will be starting on infusion treatment. Left the info in my car and can't remember the name.

Was this helpful?     1     0  
Dorianna Says:
via mobile

My doctor just diagnosed me with rheumatoid arthritis and put me on methotrexate I appreciate all the things shared I really just want to stop hurting

Was this helpful?     0     0  

Viewing page 1 of 1     Reply

More Discussions:

Methotrexate side effects nausea, vomiting, no appetite
Side effects nausea, vomiting, loss of appetite what can I do ## Hello, Alma! How are you? I'm sorry about the probl... 1 reply
Methotrexate reaction
When I take Methotrexate (7.5 mg.) for my RA treatment, I get these swollen areas in the tissue, on my lower leg and som... 9 replies
Methotrexate and a chest cold
Hello, I take .6 ml methotrexate weekly plus plaquenil and sulfasalazine. I've been completely knocked out with a he... 6 replies
Methotrexate & Coumadin
I have the beginning signs of Rheumatoid Arthritis and my doctor has prescribed Methotrexate. I have been on Coumadin fo... 5 replies
Methotrexate and lupus
My daughter has lupus. How long does she need to take Methotrexate? Her hair has thinned as well. she takes it 1x a week... 4 replies
Methotrexate elevated Creatine levels.
Has anyone experienced an increase in their creatine level since taking Methotrexate or had any kidney damage as a resul... 3 replies
Methotrexate injection
mouth ulcers, nausea, renal failure it was prescribed for arthritis has kidney diease ## How are they doing, now? Those ... 1 reply
methotrexate2 5mg tablet
What is this drug used for exactly. I take 6 of these at one time. once a week. They were prescribed by ma RA doctor. Bu... 1 reply
methotrexate & time duration in your system
I took methotrexate injections 15mg once a week for about 3 years off & on, mostly on for psoriasis & stopped co... 1 reply
Methotrexate for Plantar Fibroma
Can methotrexate be used to treat a plantar fibroma? I have a plantar fibroma about mid-arch in my right foot that is ve... 1 reply

Post a Reply

No registration needed.
Simply fill out the form below.



 Optional, stays hidden.
Get notified when a reply is posted here.

4) Text Verification: *
Prevents SPAM.

Click here to show the question

with the privacy policy (20191231).

This form will be submitted securely


Discussion Thread Guidelines: Any participation in the discussion threads signifies your agreement with the Terms of Use and Privacy Policy. (1) Act civilized and be respectful towards others. No profanity, vulgarity or lewd / suggestive content is allowed. (2) Posts encouraging, facilitating, or seeking advice about the abuse of medications or other substances are prohibited. (3) Personal contact information (such as telephone numbers, email addresses, etc) is not allowed to appear on our discussion threads. (4) We do not allow our forums to be used for buying, selling, trading, or for the promotion of a product or service. (5) Posting external links to other web sites is not allowed without our prior approval. (6) We reserve the right to edit or remove content which we find objectionable to the community at our sole discretion.

Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. This page was last updated on 1 September 2016.

We are committed to your privacy.

Copyright © 2005-2020 All Rights Reserved. MedsChat® is a registered trademark of Limelight Innovations L.L.C. 9888 W Belleview Ave #5000, Denver, CO, 80123, USA