Methotrexate Reaction

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Phyllis Says:

When I take Methotrexate (7.5 mg.)
for my RA treatment, I get these
swollen areas in the tissue, on my lower leg and sometimes in my forearms that will turn bright red (like a sunburn). It really is painful and seems to feel better once it turns red. This will last up to 4 days. Anyone out there with a similar re-action?

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nenene Says:

I know exactly what you mean! I take the medication for my lupus. My doctor prescribed over the counter hydrocortisone cream and it does wonders. Also, when it is really sore he has me take vitamin e capsules, puncture them and squirt them on the area. Believe it or not, it really does take away a lot of the pain. Hope this helps.

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betty dyke Says:

my husband passed away last year.. i have recently found a prescription which was for (100 )
2.5 methotrexate to be taken as doctors instructions what would be the symtoms if some one were to taking too many of these

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Verwon Says:

Here's the link to the monograph listing with more information for you on that:


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parameswaran Says:

Please stop taking this medthotrexate. And please go to homeopathy you have plently of medicines in homeopathy. Provided you have to be in diet. avoid taking this hell

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phyllis Says:

I've since discovered that MSG in my foods was causing me many reactions including triggering my inflamation....Everyone with RA should stay away from as many perservatives in their food as possible!!!

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my3sons Says:

IF YOU DO NOT TAKE exactly as given to u. I was told it will kill you this is not a med to play with. Hope this helped bless you on your lifes journey

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Pat Says:
via mobile

Has anyone developed lumps under the skin, mainly in the thighs, that are painful from methotrexate ? I never had this condition before being on the medication, started developing 5 months after. Dr says she never heard of this.

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Lokiosho Says:

My mother a Rheumatoid Arthritis patient has been prescribed Folitrax 12.5 mg every week- Post 3 weeks we are witnessing swelling in her feet - is this a side reaction of the medicine?

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Suresh Says:
via mobile

@post #4,

There are studies suggesting that homeopathy doesn't work.


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