Low Platelets

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Just started triple tx on nov 5, 2012. Two weeks test shows platelet count dropped from 149 to 109. Doc said we'll watch it . Is this normal?

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1

I started the triple therapy on 9/21/12 and my platelets were low even before I started (140). I am week 10 and my platelet count is 53. What almost stopped me (other the side effects) was my WBC which fell to 2.

Here is my story,
I have has HepC for 25 years and have been through two other treatments. First the Interferon, nothing. Then, in 2003, the Pegasys with Ribroviran. My viral load went undetectable after a month but came back making me a relapse patient.
Now on the triple death therapy I am virus free after week 8 but I am not celebrating yet. When I started in September I had no side effects until week four. Then the hemmoroids came. I was going to quit. A nurse just happened to call from CVS Caremark (where I get my meds) and said to drink a gallon and a half of water a day. In two days they were gone and never came back. The worst side effect is the tiredness. I have yet to beat that but I believe it is my WBC that causes that.

I can say, above all, DRINK WATER!

This is my first post and I'll be back.

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2

Have either of you had any changes yet?

What do your most recent tests show?

In such cases, it's sometimes hard to know what's causing the fluctuations, your health, a medication, a combination of both. That may be why your doctor said they'd just be keeping an eye on it for awhile. It's always possible that it's a temporary effect from starting the new treatment and that it will improve after awhile.

Learn more Incivek details here.

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3

I finished the Incivek on 12/14, at that time my platelet count dropped to 43 and WBC to 1.9 but the doc said I was not anemic.

Everyone is different but as far as I go I thought this would be the end of the worst part and it was but I was sick for 4 days after the Incivek stopped. My doc (they don't know as much as we do) said he has never heard of withdrawal effects but if you read the boards, some people do experience this.

Also, the Pegasys and Ribravirin have their own side effects and some are similar to Incivek so it's not over by a long shot - for me anyway.

The best advise I can give is WATER and lots of it. Before treatment I was not a big water drinker but with thuis stuff water is MANDATORY. One and a half gallons a day (I do two). I am starting school again in January and I hope the brain fog lets up soon (which is one side effect that is annoying). I also am very depressed and lack energy to do nothing near what i am used to. It's like house arrest.

(Remember, your mileage may vary).

Stay strong. -Dave

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4

Mine went down to 57, and hemoglobin dropped to 7.6 at week 11. Had to have a transfusion the day after my birthday! :) But I made it through, and am glad I did.

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5

" have yet to beat that but I believe it is my WBC that causes that. "

More likely, it's anemia--a common effect. How is your hemoglobin and RBC count? Hemoglobin levels become of serious concern when they drop below 8.

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