Janumet Xr (Thread 229049)

2 Replies Updated

Conversation Starter

Mary Says:

what is the differance between Janumet xr 50mg/100 mgand Glipizide 5 mg and can the be used together

Showing Replies 1 - 2 of 2 RSS Feed

of 1    
Verwon Says:

Janumet XR contains the active ingredients Metformin and Sitagliptin in a time released formulation to help better lower and control blood sugar in diabetic people.


The Glipizide is a different oral antidiabetic medication.


Has your doctor instructed you to use both medications?

They can be taken together, but only if someone is experiencing high sugar levels that are hard to control, because it increase the risk of hypoglycemia.

Was this helpful?     0     0  
David Says:

The active ingredients of Janumet XR are Sitagliptin + Metaformin. Both of these medications are used in the management of type 2 diabetes. Glipizide is generally used along with diet and exercise, and (sometimes) with other medications, to treat type 2 diabetes. The primary differences between all three of these drugs lie within the chemical makeup of each drug, as well as the addition of certain "inactive" ingredients that may or may not be present in each tablet.

Both of these factors play a detrimental role as to how each drug is metabolized and used by your body. Because everyone is different, your body may agree with one medication over the other, due to how you feel or based on whatever side effects present themselves.

In regards to taking them together, the only interaction is of that between Glipizide and Sitagliptin. This interaction states the following:

"ADJUST DOSE: Coadministration of a dipeptidyl peptidase-4 inhibitor with an insulin secretagogue (e.g., sulfonylurea, meglitinide) or insulin may potentiate the risk of hypoglycemia.

MANAGEMENT: A lower dosage of the insulin secretagogue or insulin may be required when used in combination with a dipeptidyl peptidase-4 inhibitor."

Personally, I wouldn't want to risk the interaction of taking them together, coupled with the side effects of each drug. You may want to just make some dietary changes to help make 1 drug more effective.

NOTE: studies have proved that a low fat - high carb - raw vegan diet can reverse and cure diabetes type 2, and even control diabetes type 1 without the use of medication. Just thought I'd throw that in there! :)

I hope this helps!

Was this helpful?     0     0  

Viewing page 1 of 1     Reply

More Discussions:

Janumet XR and Galvus Met 50 850 differences
I have been using Janumet XR for 2 years. And my panel doctor has passed away recently and I have changed to another pan... 1 reply
janumet vs janumet XR
I am a type 2 diabetic, my doctor has prescribed 2.5mg of glimepiride, 300mg of Invokana and 50/1000 of Janumet, I was g... 1 reply
Janumet side effects
I started Janumet since then I have been having vaginal soreness not burning sore like from being very dry ## I'm so... 2 replies
Janumet and Gliclazide
Anyone getting side effects from Janumet and Gliclazide? My husband is experiencing sore knees shoulders and dizziness a... 2 replies
Janumet 50/1000 Be Crushed
I can/T swallow the pill Janumet 50/1000 can this be crushed safely. ## As long as you don't have the time released ... 2 replies
Janumet and Amaryl Tablet fir diabetes 2
I use of amaryl for 12 years with other medications but level remained uncontrolled recently my doc perscribed janumet 1... 1 reply
janumet 50mg/500mg and glycomet gp1
I take janumet 50mg/500mg and glycomet gp1 daily.today my FBS & PP were notice at 253 & 323 respectively.kindly ...
Can I take Janumet Tylenol at the same time
I have a BAD headache, I take Janumet daily and I need to know if I can take Tylenol at the same time with the Janumet. ... 1 reply
i was on Amtas AT for 2 years and after that suddenly my blood sugar started rising. I don't have any family history... 1 reply
once daily janumet
I'm taking Janumet at strength 1000/50 twice a day. I have read that the company starts doing once daily tablets of ...

Post a Reply

No registration needed.
Simply fill out the form below.



 Optional, stays hidden.
Get notified when a reply is posted here.

4) Text Verification: *
Prevents SPAM.

Show Verification Text

with the privacy policy (20210315).

This form will be submitted securely
Privacy policy cookies information


Discussion Thread Guidelines: Any participation in the discussion threads signifies your agreement with the Terms of Use and Privacy Policy. (1) Act civilized and be respectful towards others. No profanity, vulgarity or lewd / suggestive content is allowed. (2) Posts encouraging, facilitating, or seeking advice about the abuse of medications or other substances are prohibited. (3) Personal contact information (such as telephone numbers, email addresses, etc) is not allowed to appear on our discussion threads. (4) We do not allow our forums to be used for buying, selling, trading, or for the promotion of a product or service. (5) Posting external links to other web sites is not allowed without our prior approval. (6) We reserve the right to edit or remove content which we find objectionable to the community at our sole discretion.

Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. This page was last updated on 30 March 2012.

We are committed to your privacy.

Copyright © 2005-2021 All Rights Reserved. MedsChat® is a registered trademark of Limelight Innovations L.L.C. 9888 W Belleview Ave #5000, Denver, CO, 80123, USA