Increase In Psa Levels

Bill Says:

I have used Axiron for 2 years now. T levels are in the 500-600 level on each test. My concern is around my PSA level increasing. In two years it has gone from 1.4 to 2.3....slowly increasing on each test. I am a 63 yr old male. I am concerned about the potential of the T to ignite prostate cancer if there is any in the prostate. Any feedback on this that might be helpful?

3 Replies

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Verwon Says:

Hello, Bill! How are you?

Using Axiron does increase the risk of prostate cancer, which is why your levels are checked regularly, while you're on it. However, your numbers aren't high and some fluctuations can be normal, sometimes it will even vary if your doctor used a different lab from one test to the other. This medication is also reported as being known to cause slight elevations, while a man is under treatment with it.

The FDA lists its other typical side effects as possibly including dizziness, headache, skin irritation and irritability.

What has your doctor said about it? Did they feel there was reason to be concerned?

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UroNurse Says:

Testosterone replacement therapy dose not increase risk of prostate cancer as people commonly believe. It can feed the cancer but only if it is there to begin with. As to the PSA your levels are normal for a man your age a slow increase is normal and probably just means your prostate is growing.

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Bill Says:

Thank you for the update on the impact of T on PSA and the likely hood that my PSA is increasing due to my age. My Dr is not concerned with my PSA level but I have read many articles indicating that TRT therapy should be watched closely.

Is there any research on how long a man can safely use TRT?

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