Hysingla Experience

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chronicbackpaingirl Says:


This is day 3 of me taking Hysingla 20mg after taking Norco 10/325mg three to four times a day. So far I've noticed some wacky side effects. The pill seems to kick in at around 8hrs, and I can't keep my eyes open, I get a rush of anxiety and nausea. I've taken EVERY other ER opiate in the world and none of them did this to me. I do notice that it has lessened my extreme pain already and I have taken a few norcos on top of it thru out the day, but the 8hr mark seems to be like a different world kicking in. Has anyone been on this for awhile, went thru these side effects and then came out the other end actually liking this med? I can find NOTHING on the internet regarding much experience or reviews out there on people who are taking this med. I've woken up in the middle of the night with abdominal pains, anxiety and an overall feeling of weird. Then it passes and I fall back to sleep, and I just feel so hungover. Also it's like every three hours or so it will ''kick in'' again with the can't keep my eye open thing, the nausea, etc. I started out the first two days not eating much (took away my will to eat) so today I made sure I ate a large meal before the 8 hr mark kicked in, but still feel so freaking weird! Please, can anyone out there give me some feedback?



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1
Verwon Says:

I'm very sorry about the way you're feeling.

Hyslinga also contains Hydrocodone, just without the Acetaminophen and in a time released formulation. The FDA classifies this as a narcotic analgesic, so it has the potential to be habit forming and may cause side effects, such as nausea, dizziness, drowsiness, dry mouth and constipation.

There may be a change in the amount being released at about 8 hours in, which may be causing more side effects.

However, things should improve after 4 weeks, or so, as your body gets used to it. If your symptoms don't improve, or if they get worse, you should speak to your doctor as you may need to try a different medication.

Is anyone else on this medication that can chime in?

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chronicbackpaingrl Says:

I decided to stick with it, and it's been about a week. I still get very tired, but overall my pain level is so much better. I've stopped the nausea, I do get dizzy (orthostatic) when I get up fast or something like that, but all in all things are getting better.
I still have pain and need breakthrough, and I'd be very scared to up the dose of this stuff and go through that whole intro period again.

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Christine Says:
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Yes I was on for 4 months with2 Percs for breakthrough pain hysingla is the worst drug I've ever taken for pain lost 13lbs ,malnourished depressed didn't come out of room didn't take pain away,mostly bone no muscle stayed in pajamas everyday !!! I will never take again try Percocet and maybe soma.i gained 5lbs in 7days since i stopped am happy already in one week .drink ensure or boost little walks food @ drink a lot of fluids.also couldn't sleep and couldn't go to bathroom.,and I was paying 35.00 a pill . Make sure you have some other pain pill on hand GOOD LUCK hurry get off soon. I went from 20 mg to 30 mg then when off 3 Percocets a day 2 norco hope you get we'll .

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4
jonepal Says:

I have just started taking this medicine. I was taking norco 10/325 4/day with tramadol in between. That worked great but my liver ALT started to inflate so they moved to morphine(which was horrible) then to the hysingla. For me, maybe my metabolism runs at a really high rate but it works really well when it first kicks in. Started taking it about 10pm so it works when I first wake up. It was the best I have felt when waking up in a long time. but it seems like in the afternoon it wears off for me (60mg er). So the evenings and going to sleep aren't as easy as they were with the previous regimen. Up to lnch it takes away most of the pain. It is really hard to get and more expensive than most medications. I have had pharmacists say they would not order due to the risk of addiction and abuse. I have had pharmacists say they would not order due to the obnoxious price it costs to get it (over $1000 for a bottle of 60 for the pharmacy to buy). I will be speaking with my DR on Friday to see maybe other options. Does anyone have any experience with vicoprofen and know if that may be an option?

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5
g Says:

Hi I'm on my third day of hysingla er and I too get that neauscious feeling a few times a day. 30 MLG. I have severevRa and it does help the pain. I have to admit I do miss the euphoric feeling of regular vicoprofin but I was taking too many. So this is definitely better for me. I plan on sticking with it.

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brdie Says:

I have been on vicoprofin off and on (mostly on) for about three years. Omg its highly addictive. The withdrawals are dreadful all I did was cry. I finally fessed up to my Dr because i kept running out of meds way too early. He put me on hysingla er 30 mg. Its not great but at least I don't have the ups and downs like with vicoprofin. The pain is better but definitely no euphoric feeling at all. I may ask him to up the dose but I'm going to give it a little time. Peace


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Boatslip Says:
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Hysingla er 20 makes me so sleepy I can't stand it!! Like you I'll go a bit fine and then can't hold my head up! It's like I'm physically I'll!!

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8
CO TO FL Says:

Do try and stick with it for 4 weeks as Verwon suggested. Let your body get used to IT . Good luck

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9
brdie Says:

I was on vicoorofin 7-325 about 6 pills a day. When I went through 120 in a month I knew I had a problem. I took two at a time three times a day. It helped my pain but I feel its highly addictive. So I told my doctor and he put me on hysingla er 30 MLG. Once a day. He also gives me 30 vicoprofin for breakthhrough pain. Its helped and I don't feel as addictive like with vicoprofin. Just be careful. Peace

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terry Says:
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is 20miligrams of hysingla the same as4 7.5 hydrocodones.and will it help with chronic pain?

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Cheryl Says:

Been on the 30 mg of Hysinglia for about a month. Doctor put me on it to try to lessen breakthrough pain, but it is not working at all. Was taking Norco 10/325 which were useless. Goin to ask her today to take me off the hysinglia and maybe try Percocet as she first suggested? Hysinglia just makes me nauseous all the time, have gained weight, but I don't know how since I am not even hungry. Thought this was supposed to kick in when pain was felt, but all it does is make me sleepy while I am trying to watch TV with my family. Just tired all the time. They need to go back and fix this as it does not provide 24 hrs of pain relief as advertised.

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12
ginny Says:

yes I was on vicoprofin off and for about 4 years, the problem is I got very addicted to it and was taking more to relieve the pain. I feel it does work better than vicodin and or Hysingla. I currently take hysingla er 40 mg. 1x day with 4 vicodin as breakthrough medication. Seems like a lot but the vicodin is a very low dose. I did feel that the vicoprofin worked better on emergent pain. Hope this helps.


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Kpay Says:
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First time on Hysingla ER and it is the worst med I have ever taken. I only stayed on for three days, but that was enough...hot flashes, nausea, drowsiness, out of it in general. After only three days, I experienced withdrawal symptoms when I stopped the medication. Terrible drug.

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Donna Says:

I had been on hydrocodone 10-325, 3or 4 for several years. I have had an allergic reaction to every long acting pain med my doctor tried so when Hysingla became available I asked my doctor if I could try it. I have been on 40 mg now for almost a month and feel terrible. It has helped with my back pain, but I am now experiencing more joint and bone pain then ever before. I also feel like I have the flu all the time, plus itching, rash earaches, can't eat and feeling drowsy and yet keep waking through the night. Overall I feel terrible and am going to stop today to see if these things go away and will call my doctor and inform him. I wanted this to work so badly but the trade of isn't worth it. I just don't understand because I thought it was pretty much the same as what I was taking. Feeling very discouraged!

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Donna Says:

Hi chronicbackpaingirl ,
I also was experiencing many problems with Hysingla in the beginning > see my other feed back here < . One thing I did do different was I starting taking it at night instead of the morning. I am now well into my second month and the pain relief is amazing for me. I still have to take 1 or 2 Norco's for breakthrough pain _ some days 0 . I am glad I hung in there because some of the things I thought were being caused by the drug turned out to be due to a infection from something else. I am having problems with constipation, but had that with the Norco as well and will work with my doctor on that. I only feel nausea occasionally now, I find I do better with eating small amounts throughout the day rather then large meals. But the bottom line is I now have better pain control and a sense of freedom from constantly watching the clock for my next dose_ I now have days I can actually do things without the constant interruption from pain. I am sorry that you are having so many problems on it and wondered if it has gotten any better for you? Wishing you the best~

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Juli Says:
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I am on hysingla about 4 weeks now. Note the pain level has stayed level about a 4. Severe constipation got me. I over compensated w miralax and correctol. ..don't suggest that. Now I use ducosae everythree days w Hugh if be diet. Guzzle water. I wonder if hysingla is making me gain weight. 7 lb. Since started a month ago. Really can't run can walk but have foot drop. Been doing water excercise but as seasons chan ge.. I used to compete in bodybuilding but have had man false starts do to chronic pain. I think w my latest knee replacement I should try and join gy? W bike or ellyptical. I hate to gain wait. Any clothe at the least tight hurt my back. Surgeon wants to do another fusion on l4 and L5 because they are non unioned. Anyone off aa tkr knows it is n for the faint of &eart. So back to hysingla question possibly u may b whole heartedly costipated. Jus sayinng

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10 year veteran Says:
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I have been taking Hysingla ER 60 mg now for 2 days. I have not had any side effects other than it is just now at 0700 on day 2 making me feel a rush of pain relief. I am extremely drowsy bit cannot fall asleep. I laid in bed all night last night with my eyes closed but zero sleep. I was previously on Norco 10/325 qid. For almost 4 years. Started this horrific back injury journey 9 almost 10 year's ago. I am not taking any other medications for breakthrough pain. But I seem to get the same rush aka high as I did with the Norco. Maybe your dose isn't high enough. Dr. Started me on 60 mg due to my tolerance for the hydrocodone. Might ask about that.

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Ruth Says:
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I'm having a terrible time with this drug. They started me on 40mg and I suffered severe headaches and much more. I felt stoned. I hate it. Just changed to 30mg. The headaches are awful. I understand why the doc wants to change to hysingla, but I was so much better functioning with 4 10 MG Norco. This sucks.

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John Says:
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I just started on 30mg. How long should I wait until it starts working?

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Still Hurting Says:
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I've been on the hysingla er 20 for 1 month. Well for the last 3 weeks ive had the worst headache ever and nausea every minute of every day. Even ended up in ER over a week ago for the headache and nausea. After reading all the comments and the side affects, im not taking this stuff anymore. Ive lost over 20 lbs. Not good when I was only 130 to begin with. I dont eat. And I hurt worse now then I did before. This hysingla is horrible.

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