Hydrocodone Levels Too High

7 Replies Updated

Conversation Starter

Kim Says:
via mobile

So i take hydrocodone 10/325 and have for a long time. I had my bi monthly apt and my doctor said my levels were way to high. He said i had to be getting more from somewhere. I told him i don't get extra from anywhere and i only take 3 a day. That's what i am prescribed. He did not tell me what the levels were but i am livid that he called me a liar. I take Baclofen 20 mg on top of that and a .5mg alprazolam. My fluid intake usually consists of only soda and coffee, but i have recently stopped almost all of the coffee. I was being honest my Dr. and i now get called a liar. What could be causing the high levels here?

Showing Replies 1 - 7 of 7 RSS Feed

Page of 1     Sorted By:
Verwon Says:

Hello, Kim! How are you?

If you have cut down on your fluid intake, your levels could be showing up higher due to dehydration. It can cause such a medication to become more concentrated in your urine sample. (NDC for more medication information 52544-539).

The FDA warns that it carries the risk of being habit forming and may cause side effects, such as nausea, dizziness, headache, constipation, and dry mouth.

How much fluid do you take in each day?

Was this helpful?     0     2  
Kim Says:
via mobile

Re: Verwon (# 1)

Dont drink hardly anything and was only drinking soda. Have started drinking water and only drinking 2 bottles a day right now and im always tired to

Was this helpful?     0     0  
Mason Says:

A lot of times these high readings can be due to other medications, whether they are OTC or prescribed. Certain medications can mess with the metabolism of other medications. This could make a particular medication build up in your system as it is not being metabolized fast enough. This could result in a higher than normal reading.

For example, grapefruit/grapefruit juice is known as a cytochrome P450 3A4 (CYP3A4) inhibitor. This is the same enzyme that breaks down xanax for example, among many other prescription drugs. There are many other drugs that inhibit CYP2D6/CYP3A4 as well; such as tagamet (cimetidine), clarithromycin, telithromycin, nefazodone, itraconazole, ketoconazole, atazanavir, darunavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, tipranavir among many others.

Although only a small percentage of Baclofen is metabolized by the liver it could be enough to inhibit either liver enzymes CYP2D6/CYP3A4 just enough to cause a build up in your blood/plasma. However, I'm not a doctor or pharmacist but I have read a lot about drug/food interactions and how they can relate to how liver enzymes can increase or decrease the amount of a drug in your system.

Bottom line is that CYP2D6/CYP3A4 enzymes are the first line of metabolism against Hydrocodone. If you're taking anything that may inhibit these enzymes it could result in delayed clearance of hydrocodone from your system.

Was this helpful?     0     0  
BL Says:

You can get a copy of your medical records and read the lab report.

Was this helpful?     1     1  
Kim Says:
via mobile

BL (# 3) --

Ok im gonna try that. Thank you very much. Do i tell the Dr i need copies or who do i tell?

Was this helpful?     0     0  
BL Says:

Re: Kim (# 5)

You can call your doctors office and ask to speak to the person in charge of medical records. They can charge you a fee for copying the records. Federal Law governing patients access to their medical records is at the link below.

Your Medical Records-

Was this helpful?     1     0  
Kim Says:
via mobile

Re: BL (# 6)

Ok. Thank you very much. I was very upset when he may as well told me i was a liar. His words were the only reason they are too high is because you have to be getting them from someone else :(

Was this helpful?     0     0  

Viewing page 1 of 1     Reply

More Discussions:

Theraputic Blood Levels Length Of Time Hydrocodone
Script for 3 hydrocodine a day (750mg). Don't always take but get script. Blood work in 2 weeks. If I take prescribe... 1 reply
high tolerance to hydrocodone and lyrica
I have a high tolerance to hydrocodone but have a 5mg norco and a 300mg lyrica. If I take them both will I feel the hydr... 1 reply
hydrocodone should it be highly restrictive
Why does oxycodone come in higher doses than hydrocodone?
I'm trying to manage pain for degenerative stenosis and see that hydrocodone is usually in 5 or 10 mg pills, while o... 1 reply
took hydrocodone 16 hours ago no opiate withdrawals when can i take suboxone
Been on suboxones for over a year. I stopped taking them for a week because of some dental work. I was in so much pain n... 6 replies
Took hydrocodone 24 hours ago. When can I take zubsolv?
Yes I know you need to be in "withdrawal" before you start. I have been taking 30 to 50mg of hydrocodone for ove... 2 replies
tooth hydrocodone
I took 2 10mg hydrocodone 325 acetaminophen for the pain of wisdom teeth coming in. I understand to drink as much water ... 1 reply
Took 10mg Hydrocodone 6 hrs before 1st appointment
Hello. I am going to my 1st appointment to a Dr. That prescribes Suboxone to try to get my life under control. I have be... 2 replies
i took 10 5 500 hydrocodone
I have a pretty big tolerance and took thought that I needed to take around 10 to feel anything I then looked it up and ... 1 reply
hydrocodone acetaminophen 5/325 for a toothache
I took a 5/325mg hydrocodone for a toothache. It's been half an hour and no pain relief yet.. I haven't slept fo... 3 replies

Post a Reply

No registration needed.
Simply fill out the form below.



 Optional, stays hidden.
Get notified when a reply is posted here.

4) Text Verification: *
Prevents SPAM.

Click here to show the question

with the privacy policy (20191231).

This form will be submitted securely


Discussion Thread Guidelines: Any participation in the discussion threads signifies your agreement with the Terms of Use and Privacy Policy. (1) Act civilized and be respectful towards others. No profanity, vulgarity or lewd / suggestive content is allowed. (2) Posts encouraging, facilitating, or seeking advice about the abuse of medications or other substances are prohibited. (3) Personal contact information (such as telephone numbers, email addresses, etc) is not allowed to appear on our discussion threads. (4) We do not allow our forums to be used for buying, selling, trading, or for the promotion of a product or service. (5) Posting external links to other web sites is not allowed without our prior approval. (6) We reserve the right to edit or remove content which we find objectionable to the community at our sole discretion.

Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. This page was last updated on 20 December 2017.

We are committed to your privacy.

Copyright © 2005-2020 All Rights Reserved. MedsChat® is a registered trademark of Limelight Innovations L.L.C. 9888 W Belleview Ave #5000, Denver, CO, 80123, USA