Hydrocodone-acetaminophen 10mg/325mg Overdose Effects And Safety

APRO Says:

Male 210lbs - takes whatever whenever, but is taking over a dozen hydrocodone-apap 10mg/325mg pills in 24 hours. Is that bad? What's bound to happen?...What if he takes oxycodone 15mg also?

25 Replies (2 Pages)

Page:1Last Page
Earliest Newest Votes
Jenna Says:


From what I am seeing, daily consumption of hydrocodone should not exceed 40 milligrams in patients not tolerant to opiates. The PDR from 2006 states that Norco 10, containing 10 milligrams of hydrocodone and 325 mg of APAP (Acetaminophen) can be taken at a dosage of up to twelve tablets per day (120 mg of hydrocodone). This restriction is only limited by the fact that twelve tablets, each containing 325 mg of APAP (Acetaminophen), puts the patient right below the 24-hour FDA maximum of 4,000 mg of APAP. Some specially compounded products are routinely given to chronic pain patients in doses of up to 180 mg of hydrocodone per day.

That being said, the amount of pills he is taking is very likely over the FDA maximum, which is quite dangerous. He should only take the amount that has been prescribed to him by a doctor.

I hope this info helps, please post back if you have any more questions so I can further assist you.

Was this helpful? 1
jack Says:

What if they get just say.....20 hydrocodone Friday they r gone by Sunday...Monday they get 20 oxycodone 15mgs they r gone by Wednesday....Wednesday they get 10 oxycotin 40mg which r gone by Friday that's insane or is it me

Was this helpful? 4
MCG Says:

I know pain can be bad, but Taking that many pills in one day is definitely bad. That's an addiction. Be honest with your dr and they may prescribe stronger mg to take less in a day. On second thought, they will send u to pain mngmnt where they will probably give something other than what u like. But 16 is very bad. Make sure to take a liver cleanser.

Was this helpful? -1
Senor Skunk Says:

MCG is right. That is far too many pills; that much acetaminophen will do a number on your stomach and make you grind your teeth like crazy.

If you need that many pills for pain relief, ask your doctor for something else. If you're hooked on them (and it sounds like you might be), be honest with your doctor. There are meds that help you to come down gradually, and then your doctor can get you onto something else.

My former neighbor in San Diego bought a three-month supply of 1mg Tafil (Xanax made by Pfizer in Mexico), and went through them in three weeks. Many Mexican doctors will write you for as many as you want, but even then the doctor in Tijuana wrote him for something to help him get off the stuff for awhile before prescribing Tafil again.

Was this helpful? 0
Sher Says:

That very well means you need help because you are a full blown addict and you will kill yourself.

Was this helpful? 3
john Says:

I take 12 a day prescribed by my dr. I also Tak 20 my oxytocin 2 times a day hope I will be ok

Was this helpful? 2
MCG Says:

12 in a day??? Bad depending on how you feel when you run out... Feel like crap? Trying to refill before you run out? Running out of money? Then it's an addiction. The body needs it. The body LOVES it, but 12 in a 24 hr period is about the max. If you can take 12 in a day, that also means you have been taking for a few weeks and even months. Gets even worse when you mix with muscle relaxants. Feels great huh? Only you know the truth... Time to stop. See your Dr.

Was this helpful? 1
BL Says:

12 a day is 3900 mg of tylenol. The FDA max in a 24 hr period is 4000 mg tylenol. I hope your dr does routine liver function tests on you.

Was this helpful? 1
Redhead 57 Says:

MCG, I know this is from back in September but I just wanted to say: I take "8" Norco 10-325mg, "6" Robaxin 750mg, "2" Mobic 7.5 mg, "2" Effexor XR 75mg , & "2" 150 mg Lyrica every day just for my osteoarthritis & I have been for at least 7-8 years. I go to my pain doctor for this medication & I just found out yesterday that I now have rheumatoid arthritis also!! These medications do not "affect" me, make me high, loopy, or anything else!! I am just in severe pain & it's just what I need to get me thru the day. It doesn't totally alleviate my pain -- it just lessens it!! I have many other health problems that I take medication for (not painkillers) & I do not have any control over "having" these health problems!! I just do the best I can every day & that's all I can do. The medication I take is between me, my doctor & my Heavenly Father -- & no one else!! The previous statement is also what I tell my husband who is a 35 year veteran police officer. That's all I have to say. I just get tired of people judging others when they can't possibly know how someone else feels. Thanks for letting me vent!!!

Was this helpful? 13
BL Says:

Redhead 57, your dr is exceeding the recommended dosage. And even though you have been taking this med in this dosage for 7-8 yrs, your dr may not be able to prescribe it for much longer the way you're taking it. There is a new med that has only Hydrocodone in it and it is time released, so you only take 1 every 12 hrs. You may want to ask your dr about Zohydro

Was this helpful? 2
MCG Says:

No problem venting. I understand pain very well. Marine Corp and U.S. Navy vet, 20 years of service. Been shot, stabbed, and an emotional rollercoaster you couldn't understand unless you were there. Many, many others that were in my field suffer the same problems. Judging people is different from judging one's actions. I know wounded warriors in far more worse pain than you and climb mountains, swim and bike miles a day, and find time outside of work to help addicts get better. You know if your an addict. It's a sickness. In all honesty, I feel nothing is wrong with popping the top off a cold beer, pouring a glass of wine, or popping a pill or two if it helps you to focus or get a job done or even to tolerate a bad situation, but YOU cannot make excuses! You know if your an addict and if you can live with it, then your right, it is between you and your dr, who already knows your an addict; just ask him or her, and between God. You see, if your dr tells you one day there is a natural way to help yourself heal so he or she won't prescribe Meds anymore, your gonna have a cow! Now I'm busy seeing patients, but often times these forums are educating. Feel free to reply. Much more to say... You found yourself on this forum for a reason? On this website for a reason.

Was this helpful? 4
melinda Says:

what dr do you see I have been looking for pain management for a couple of months

Was this helpful? 1
Know my drugs Says:

That means he's not in control. He's taken them not as prescribed I have c4-c8 nerve damage plus other bone problems I take my pills as prescribed if you don't. Then you run out & going out & getting more drugs. That's not being in control. Your letting the pills control you it needs to be the other way around

Was this helpful? 0
brent Says:

Pain management is a ripoff and they suck

Was this helpful? -1
tony Says:

Dam where r u from n I wana party with you!!!!!

Was this helpful? -4
Jt Says:

If he continues, his liver can be damaged severly, too much ! Is he in that much pain?

Was this helpful? 1
Nikki Says:

You are addicted to them. Be prepared to go through withdrawals when u stop. What kind of respected Dr. gives a patient that much drug at one time? BE CAREFUL

Was this helpful? 2
john Says:

i started 6 years ago 2 7.5 a day and then 3 and then 4 now i'm at 7-10 a day but i never go obove 10 no matter what and i'm starting to feel like what do i do i have fractured spine no cartidge in both knees surgery twice L4 L5 out of wack so i need someone to tell me am i out of control.

Was this helpful? 0
Tutie Says:

if someone takes 10/325 mg of norcos and you took 150 pills how much is that in mg is that in all.

Was this helpful? 0
Jet Says:

I hear you and totally agree! I have the same medical issue as you. People just don,t know what we have to deal with. My pain dr. Prescribes Vicodin and truthfully that's all that works. Hang in there

Was this helpful? 0
Page:1Last Page

More Discussions:

Dilaudid and Hydrocodone 10mg + Acetaminophen 325mg

I have severe stabbing pain in my shoulder. When the pain starts my blood pressure shoots to 220/140 with a 133 pulse. I...

color of hydrocodone10mg and acetaminophen650mg

color of lorcet 10mg/650mg ## White HYDROCODONE 10/650 ## I have chronic neck pin ## What are the markings on the tablet...

hydrocodone acetaminophen 10 325 side effects

What secondary effects can the Hydrocodone/Acetaminophen 10-325 cause to one's organism while taking them for 6 cont...

Hydrocodone/Acetaminophen (10-325) Allergy or Side Effects

I took white oblong white 10 hydrocodone / 325 aceminophen and my body feels like i have ants crawling inside all over m...

what are side effects from mixing hydrocodone acetaminophen 5 325 with oxycodone

What are the side effects from mixing hydrocodone acetaminophen 5 325 with oxycodone acetaminophen 5 325? ## I have mixe...

hydrocodone/acetaminophen 5-325mg vs ibuprofen 100mg

Which is better to take for relieving pain from a pinched nerve (hydrocodone/acetaminophen 5-325mg or ibuprofen 100mg)? ...

Hydrocodone-Acetaminophen 10-325mgs

I use it for pain relief after lumbar spinal fusion for L5-S1. My pain is in the right leg this time and is worse at nig...

hydrocodone 10/acetaminophen 325MG

oblong yellow scored on one side with a V and the other side with 3601 ## what is the strongest hydrorodane ## The stron...

Will Hydrocodone Acetaminophen 5 325mg Reduce Swelling

I would like to know if this Rx will reduce swelling. Monday, I had Oral surgery for the removal of a tooth and this is ...

360oz Hydrocodone Acetaminophen liquid (7.5-325mg/15mL)

My daughter is 12 and her weight is 160lbs and she had surgery and they gave her 360oz of hydrocodone - acetaminophen 7....