Generic Opana-people Speak Up (Top voted first)

Updated

They are saying that the new opana works as well as the old. There are so many peoples statements that I have read saying the new don't work as well but yet Endo states their research don't prove that. All people who have a real medical problem that causes pain and takes new opana and it doesn' work as well as the old needs to speak up. One person can't change anything. People who are being treated awful by medical doctors and pain clinics because they have pain also need to speak up.

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97

I was on the Opana Er 30 mg & Opana ir for BT pain when they changed the formulation to keep their patent in 2012. To the person who said is it better to be abuse proof/not work or not, the people who abused it found a way around it, so there was a outbreak of HIV, if that doesn't answer that. I have a long history of GI problems, when they abruptly changed they burned from swallowing, all through my entire body. I am still suffering from the damage those plastic ones did to my stomach. I was staying with my son who is in the military in another state when the change occurred, so I couldn't see my Dr immediately. I tried drinking bottles of pepto & anything I could think of, but they felt like fire. I finally read on the internet that Afrin will dissolve it, so I put it in a Afrin bottle & sprayed, even though I am phobic of things in my nose, I was that desperate! I got back to my Dr, flushed those evil pills, & was put on MS Contin, significantly weaker due to the extremely low bioavailibilty of oral morphine, 10-30%. But I was so happy to flush those Opana's, as they did permanent damage. I'm also sick of being in pain, misunderstood by everyone but CPP's, & I totally disagree with the person who feels every day above ground is a good day. WHY? I've lost everything, including my identity, & if you can be happy existing with nothing normal in your life, while being in constant pain & treated like a criminal for it, more power to you. I'm only alive to not hurt my son & his baby girl because she's unnaturally strongly attached to me as a mom figure since I have raised her with her Dad, who works, gets deployed, etc. Meaning I've been with her the most in her life thus far. We were watching Aladin & I asked her what would her 3 wishes be if she found the lamp. She said "The first is that you would not be sick anymore".....I didn't hear the rest I started crying. No longer in pm, I rarely make it out of the bed & she misses me occasionally doing things with her I can't do anymore.

UPDATE: Endo, the original manufacturer of Opana were found to have changed the formulation just to hold onto their patent (I never read it mentioned the original Opana was built around the abuse proof TimeRX that was later put in Oxycontin, so why the change if it was already abuse proof?). So the generics were made for Opana Er, Teva, Sandoz, etc. IN 2016 that was overturned, no more generics, Endo will hold their patent until 2023. For those of you that think the FDA, pharma co, DEA, CDC, might be a little corrupt, you're wrong. They are more corrupt than you could EVER imagine. Public health is of Zero concern, just money. Politicians and FDA are paid by the pharma co & have stock in them.

UPDATE: For those of you sick of being treated like a junkie while you suffer constantly in CP, the new DSM update defines addiction as anyone with a physical dependence. THIS is untrue (Drs actually walked out refused to participate in the updating of the DSM). Addiction is when people around you suffer from your drug taking, not benefit from it, as in the case of CPP's. Why would they do this? (Notice the media lying about the CDC stats on OD's, 6,000 people per year die of opiate RELATED deaths, suicides included. Polydrug use cannot be attributed to one drug, opiates. 500,000 plus Americans suffer from true CP, WHERE IS THE REAL EPIDEMIC? Most are under medicated, or not at all. The reason the definition was changed for addiction to include anyone taking opiates...the woman in charge of the updating of the DSM, which is the Drs Bible & INSURANCE bible, works for a pharma co developing......A NEW ADDICTION DRUG! The media, etc...,get ready for the future which is in TREATMENT OF ADDICTION...and that includes CPP's. My friend with MS killed herself last Christmas Day, look for more of the same in the future, things will get worse in the future & no speaking out or advocacy can change anything, the politicians, FDA, DEA etc etc are ALL in the pockets of Big Pharma. Peace, J

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People who believe the old Opana worked better than the new should write to Endo telling them so. Please druggies stay away. We who have pain from bad accidents and cancer have been hurt enough by people who use it for fun. Doctors and health employees treat patients awful if they find out you are taking a strong pain medicine. FDA will be judging if the new works as well as the old. Everyone with health issues needs to contact FDA and Endo and tell them.the new doesn't work as well. The new doesn't give pain relief as soon and it doesn't last as long. If you don't voice your concern's now then say good bye to something that helped you be able to have a life. Go to work, spend time with your family, etc. because you will not feel good. The pain will keep you at home.

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93

I have been on Opana 40s ER,for more then 10 yrs.and I do run into times when I get break through pain and feel like this med don't work,but I can answer that one just stop taking one or two does and you'll soon see that you go into some nasty withdrawal .So they do work.I never abused my meds and have even been taking the name brand opana which I think was stronger but then again I go by pain relief not what type of buzz I get.I don't get a buzz on my meds and I'm not looking to get a buzz just pain relief.

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106

You want to know how I feel about the people misusing and overdosing on Opana ER? I DON'T CARE!!! Nobody forced it on them. I need it, 20 mg Opana ER and Percocet 7.5/325 mg is all that I was taking. June 6, 2017 my dr stopped ALL of my meds that were required for a failed back syndrome and severe sciatica. All of my other lumbar vertebrae are herniated. I never failed a U/A and never called for an early refill. I'm very bitter and nothing helps this pain.

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33

Nicky, here is the explanation for how the doctor and pharmacist can be "technically," correct.

The new name brand Opana ER contains an extended release version of oxymorphone and tamper resistant chemicals. The old version of Opana ER only contained an extended release version of oxymorphone. The generic versions of Opana ER , known as oxymorphone ER, are based on the old formulation. So generic Opana ER a.k.a oxymorphone ER is equivalent to the old name brand version of Opana ER, which is no longer made.

So, name brand Opana ER contains oxymorphone and tamper resistant chemicals, while generic Opana ER a.k.a. oxymorphone ER does not contain tamper resistant chemicals.

Therefore, in a very stupid, but technical way, Opana ER and generic Opana ER(oxymorphone ER) are not the "same," medicine and oxymorphone ER is not the generic of Opana ER.

Basically, the argument boils down to this. Opana ER has tamper resistant chemicals and oxymorphone ER does not. Therefore oxymorphone ER is not the generic of Opana ER because it lacks tamper resistant chemicals.

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85

It's amazing how long I've been disabled and in chronic pain.I take opana,40mg.ERs,and they seem to help,BUT even with this pill I'm still in pain.When I get up and that could be any time,because my life and bed time is so messed up I never know if or when I will sleep.Needless to say,I have to take my pill right out of bed and lay on my couch for at least an hour before it feels good enough to move.
I been dealing with pain for so long,I'm really frustrated just trying to deal with my daily life.I really think the Opana doesn't do as good as they used too.I'm at my wits end trying to deal.I live on my couch for the most part,and I have lost almost everything in my life because of this disability/pain and yet most Drs. treat you like a criminal.They should be where I am and I in their cushy lives.
I still get some pain relief but I also have see a Chiropractor every week,and my pain Dr. for trigger points and Epidurals.This is some hell of an existence to live while life passes you by.The least a doctor should do is try to make people like us more comfortable.Most people will never know what you lose and how hard it is to just get through One day,to the next.No one should have to live like this.Time has changed me and my pain levels,but they never go away.I even tried smoking pot,and I can say when your head gets so full of pain,pain,pain,it makes me feel a lot better to get a break away from the boom,boom,boom.
I can say one gOOd thing,my Dr. agrees with me if it makes me feel better,and it does he says do it,,but I wouldn't use it everyday either,just when my head gets full of that pain cycle and I get tired of dealing with it .I'm glad my Dr. get's the point of how I live...I just pray one day I will be pain free,even for one day.I wonder what NORMAL feels like.I do hope doctors read what we write on these pages.Maybe just maybe one of them could feel some compassion for people like us and spread the word.We aren't druggies by choice....

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51

Here is another link to verify what CPP says is true:

americannewsreport.com/nationalpainreport/lawmakers-urge-fda-to-block-generic-painkillers-8819131.html

Also, the FDA has already held a hearing on opioids and was basically forced to listen to only people who hate opioids and want them only used for treating cancer pain. Here is a link to the hearing ( ALL CHRONIC PAIN PATIENTS MUST WATCH AND BE AWARE!)

1) tvworldwide.com/events/fda/130207

Here is a link to the petitions and other paperwork the extremist puritanical group PROP gave the FDA:

2) citizen.org/documents/2048.pdf

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71

Why is it a problem that it's flammable? Do you intend to swallow a lit match?

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84

Yes passing the plastic through the stool freaked me out, considering I have chronic constipation from the years I've been on opiates. Sometimes I go once every 2 weeks even though I am on several medications to combat that. The thought of 2 weeks worth of plastic coating inside of me for so long scared the mess out of me. I know some of you are like 2 weeks? !!! When your GI tract muscles are not moving the waste the only side effect for me was bloating. It seems like they are creating more dangerous medications to combat the potential abuse of certain medications. Which is more dangerous? The potential for abuse or the measures they are taking to prevent abuse?

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101

I just found out the FDA is taking pans Er off the market!!! People were misusing the new formula, so where does that leave real pain patients that it works for!!! Fentanyl should be removed before anything else!!!

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102

I take opana ER for severe pain. I do not abuse it. I am in a pain clinic. I have tried the generic brand and it doesn't work for me if it wasn't for my medication I would not be able to walk. My leg was ripped off in an accident. They reconstructed it. I got to keep my leg and without the opana ER I would not be able to walk. I have been through physical therapy twice for it but it didn't work. I also have severe back problems. It's not right to take it away from people who really need it. It's not our fault they share needles and get aids. Lock them up and teach them a lesson. Don't punish the people that need this medicine.

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103

I agree, until they were taken off the market. Also, yes the best pain relief I have ever had. Now here we go again. They are taking them all off the market. I have been on opana for years. One pain management Doctor the whole time. I for one am sick and tired of being a victim from people who abuse their medication or people who sell their medication. Those of us that REALLY are in chronic pain and suffer drastically are victims, bottom line. I have had my dose raised one time only since taking opana generic at this time. Now there taking it completely off the market - all opana & all oxymorphone. I have no idea what I will be put on, but I do know it surely can't give me the relief I get now, like someone else said. I also get the epidurals and other products along that line. 72 shots to be exact. I've been through physical therapy. I don't get, nor am I looking for a buzz. I just want pain relief. So I do not know a lot about other pain medication. I have taken Vicodin & Percocet after my first surgery. It surprised the surgeon and me that it was cancer, not what I went in for. Not to mention fibromyalgia, degenerative back disease, R. Arthritis. I can go on but won't. So anyone that can give me an idea of what works and what does not, thanks. Very angry all opana/oxymorphone is being pulled from the market.

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107

Oxymorphone IR 40mg. Are available in generic form! I have been taking it for nearly a year now! I take the Orange 40mg. 3x a day and I take the oxymorphone IR 10mg. generic (pink in color) 4x a day. Have had no issues besides my pharmacist having to order them Wich has never taken more than 24 hrs. (In Florida anyway). So it IS available people. Look it up on your insurance or call them and check if they cover them. Mine are about $80 for the ERs and $10 for the IRs. So don't let your pharmacist tell you that they do not make them! Have been getting them for a year now.

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This states that If they have to name one opioid as “most dangerousâ€, then it would be methadone because of its relatively short duration of analgesic effect and long biological half life.
Which Opioid is the Worst Opioid?

by admin | Posted in: Clinical, Pharmacy and tagged Clinical, FDA, Opana, Opioid, pharmacy, Phil Walls, prescription drugs, Workers' Compensation

by Phil Walls, R.Ph., Chief Clinical and Compliance Officer

MSNBC recently published an article entitled “Rural America finds new killer in drug Opana®â€. The article indicates that “Opana is the hot new prescription drug of abuse, sometimes with tragic consequences.†It has been pointed out in numerous articles and presentations that deaths associated with prescription drug abuse now outnumber those from heroin and cocaine combined. This is all too true in rural America, and attention is being focused on Opana. Opana contains the ingredient oxymorphone. Opana ER replaced OxyContin® as the choice for abuse for one simple reason – Purdue Pharma, which manufactures OxyContin, released a re-formulated OxyContin last year which makes it more difficult to chew or crush than the original version. This re-formulation was a direct result of the FDA’s Risk Evaluation and Mitigation Strategy. Chewing or crushing is what enables the drug abuser to experience the euphoria associated with ingesting or injecting a high dose of an opioid. The good news, if there is any in an article of this nature, is that REMS also applies to Opana ER. As a result, the old version of Opana ER is no longer being produced as of late last year. In fact, the only Opana product available from the myMatrixx mail service pharmacy is the new version which is similar to the re-formulated OxyContin in that it is difficult to chew or crush. So what happens if both OxyContin and Opana ER have been re-formulated?

Several consequences may result: 1) the sales of Oxycontin and Opana ER should decrease if they no longer provide a convenient source of high dose opioid for intentional abuse, 2) the drug abuser may seek out heroin or other illicit substances, 2) the drug abuser may find alternatives to their prescription drug of choice, or 3) the drug abuser may find ways to bypass the new formulations of OxyContin or Opana ER. Unfortunately the internet has turned into a resource for drug abusers that fall into the latter category.

I heard Opana described as much more dangerous than OxyContin recently (largely I believe because of the article referenced by MSNBC), and that made me question whether or not one opioid may be more dangerous than another. In my opinion, here are my conclusions on this question:

All opioids are dangerous.

The euphoria created by opioids is dose dependent, which means that an addict may get “high†from an injection of heroin or from intentionally consuming large quantities of an over the counter opioid such as dextromethorphan. Yes, I just said over-the counter opioid.

It is true that one opioid may be more “potent†than another. However, dose (or the amount consumed which is dependent on access) is more important that potency when it comes to abuse.

The real danger in terms of side effects such as respiratory depression and death lies in drug characteristics other than potency. This includes the long biological half-life (the amount of time it takes for the body to eliminate half of the drug) of a drug like methadone, or the ability to by-pass a drug’s “extended-release†formulation. The latter has included crushing or chewing drugs like OxyContin or Opana ER (although the new formulations make this more difficult) or the intentional misuse of Duragesic® or fentanyl patches. The latter I have heard described as “fentanyl tea†in which the patch is “brewed†as in the making of a cup of tea. I am also aware of emergency room incidents in which the abuser has severe burns caused by the application of a hot iron to the patch in order to cause rapid release of the fentanyl.

With all that said, I repeat, all opioids are dangerous. I wish there was a simple solution where I could recommend that certain opioids should simply be blocked from your formulary. However, there are steps that can be taken to minimize risk:

Monitor early use of opioids through our ARM program,
Consider the use of step-therapy in the approval of opioids,
Adopt patient-provider agreements (aka, narcotics contracts) as policy for the use of any opioid,
Monitor the daily morphine equivalent dose through our myRisk Predictorâ„¢.

If I have to name one opioid as “most dangerousâ€, then it would be methadone because of its relatively short duration of analgesic effect and long biological half life. This combination makes it very easy for a patient or drug abuser to inadvertently suffer an overdose and possibly death.

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Hi,

I received my Opana 40 mg generics today through my pharmacy. I can't say how thrilled I am to finally have this kittens in front of me. The 40 mg is round with an orange color w/ G74 on one side. This will go nicely with my A 214's. I'll post some more information after I'm done celebrating.

Moon

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20

It's been 3-days since I've been on the Impax 40 mg ER's. So far these have been my observations.

1. Efficacy and analgesic effect of these kittens are far superior than the Opana TRF formula.
2. So far no side effects compared to the TRF's. I started having serious abdominal pain when Opana reformulated their pills, so I had to abandon this drug. Looks like Impax did an excellent job of making theirs just like the original Opana. Awesome!!!
3. For all you snorters: {edited for safety reasons}
4. Just me, but thankfully my pain has decreased dramatically since I started this generic. Even my PM couldn't believe the effect of this drug from the manufacturer.
5. 60-pills only cost me $5 thanks to my insurance plan. That's hard to beat compared to Opana.

Cali Moon

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41

Martha. Your pain management doctor can write a prior authorization stating that you need the generic oxymorphone to manage your pain. Make sure that he writes the prescription as "oxymorphone 40mg ER." It will also help to print out the page from the Global Pharmaceutical website that lists the generics and the strengths that they come in. I had the same problem with my insurance company. It takes a little extra work from your doctor, but most PM doctors will take the time to make sure you get what will work best for you. I hope that this helps you!!

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42

By the way, the generic oxymorphone is absolutely wonderful at relieving my pain!! I am prescribed 1-40mg, plus 1-20mg to be taken every 12 hours. I am also prescribed 3-10mg oxymorphone IR's for breakthrough pain. I very rarely need to take the IR's because the ER's in generic form manage my pain just fine!! Best of luck to all of you who want to be switched over to the generics. They are the best pain medication that I've ever been on, and I've been on everything in the past 7 years.

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47

Who ever you spoke to wasn't paying attention to what you said. I called them and looked up on their web site for 40 ER and they do not make them. Global is the only company that won their law suite to make the stronger Opana's as generic. There are other companies to follow this year but later in the year if the FDA and Endo doesn't stop them. Endo had stop generic from coming out last Sept. but couldn't stop it from coming out this year in January. Activis was only granded to make the 7.5 ER and 15 ER. Below is what I found on there web site.

I find it strange that they won't pay for generic because my company is showing it is $150.00 cheaper than the brand. It seems they would save a good bet of money if they would like people receive the generic.

Product Category
Brand
Generic Rx
Over-the-Counter (OTC)
Oral Contraceptives
Injectables
Product Search

search by category
Products matching "oxymorphone"

Page 1 of 1

Product Name Description Additional Information
OXYMORPHONE HCL ER
OXYMORPHONE HCl ER 15 mg TABLETS 100s
NDC: 00228-3262-11
*Compare to: Opana ER® U.S. Prescribing Info
Medication Guide
OXYMORPHONE HCl ER 7.5 mg TABLETS 100s
NDC: 00228-3261-11
*Compare to: Opana ER® U.S. Prescribing Info
Medication Guide

*Brand names are the trademarks of the products' manufacturers and/or owners.
**Products illustrated may not appear at actual size and/or exact color.

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52

The government and FDA are still accepting comments from everyone on the following issue. All pain patients should comment.

regulations.gov/#!docketDetail;D=FDA-2012-N-1172

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