Generic Buprenorphine 54 411 Vs M 924 (Page 2)

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I've been going to a clinic for almost a year now and each time I get prescribed 8mg Subutex. When I would fill my prescription I would receive 54 411 white tablets. Today when I picked it up I got M 924 white tablets. The only difference I've found is the manufacturer. The manufacturer for the 54 411 is ROXANE and for the M 924 is MYLAN. Are they pretty much the same pill just different imprint/manufacturer?

221 Replies (12 Pages)

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21

Personally, buprenorphine in my book is the worst drug that ever hit the market. For a true chronic pain suffer like myself we have been subjected to this drug that does nothing for moderate to severe pain. I have put up with this disgusting thing for 2 years. Finally I told my doctor at my last appointment this is ridiculous the side effects far outweigh the 15 to 20% pain relief it offers. He said well I will give you to 10 milligrams of percocet a day and that's it. I told him that was incredibly ridiculous and at the lowest level I've ever been on in over 15 years. He said, too late already wrote the prescription take it feel it or don't. He's a crappy doctor who has over 4,000 patients and does nothing but write scripts for buprenorphine while collecting offer insurance companies. On the other hand if you do suffer from opiate addiction through other misuse and abuse or Simply the fact that you took it for a surgery and continued to want it other than needed after you are healed, then this is the drug for you. Because you do not actually require pain relief, you require a relief from opiate addiction. I on the other hand Have never drank, do not smoke, do not have any Addictions nor does any single member of my family or my extended family. But due to the massive epidemic of opiate use and the abuse of prescription pain pills significantly higher since 2004, people like myself Are literally dying because of the lack of pain relief we receive. Two of my friends in my group has already killed themselves over it. So why everybody is slapping each other on the back and they're all smiles and they're thanking God that there are over there opiate addictions, I want you to consider this. Individuals with chronic pain are no longer being treated. It is now assumed that everyone that walks through a door with or without documentation Is simply turned down. Just to let you know, I have loved scoliosis 6 vertebrae that her twisted 5 herniated discs, fibromyalgia and a top it all off the cherry on the cake of my day I have also had crohns for over 15 years. Now imagine me getting a whole 20 milligrams of freaking percocet a day to handle that pain. Congratulations you are sober, congratulations I'm in my garage screaming at 4 in the morning so I don't wake my husband up. Oh and did I mention I live in Salt Lake City Utah, so not only do we have our doctors assuming every single person is a drug addict, but we also had a religious background Interfering By bias and opinion and judgment instead of practicing medicine. Somebody told me to try kratom. That would be the equivalent of telling me to try bath salts. Incredibly dangerous Incredibly wrong and soon to be incredibly illegal. So why I do feel for people with drug addiction, Where are the headlines that are talking about the rest of us with real chronic pain that will never go away. We can have surgery after surgery after surgery, but a lot of these things are not surgically repaired they are just a life sentence. Does anybody know a real pain management specialist in Salt Lake City Utah area? & I am NOT talking about some doctor who took a 3 day course to get his what is it 2008 a certificate so he can prescribe buprenorphine. Like I said it does not cover moderate to severe pain. Talk to somebody with real chronic pain and they will tell you we don't feel high off of drugs and we don't abuse them because we need them. They save our lives. They enable us to do something as little as folding a load of clothes Or Make dinner. Something as easy as changing the sheets on the bed. We are isolated because we cannot get out as much as others And we are isolated because we must decline social events due to our pain. Now we are isolated in a world that will no longer treat that pain. Obviously the pharmaceutical companies are busy making such a dime On buprenorphine and heart medication high blood pressure medication and diabetic medication because nobody Is prescribing an opiate anymore. No I'm not going to think positive and I'm not going to meditate and I'm not going to do yoga Because paying takes up three quarters of my brain space. Change my diet I have the most holistic diet on the planet! So anybody know a real doctor in Salt Lake City that is actually still practicing the science of medicine or have they all crawled into a hole and decided to just do it the easy way.

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22

Where do you go to get the 54 411 by the Roxane brand, I have had the same exact issues as the others.

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23

If subs work for someone, they work. And drs cant switch you from suboxone or subutex. It's the other way around.

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24

Wal-Mart charges me $140 for 56 of the Roxane 54 411s but I use a discount card.

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25

I dont know Jeremy how you would have info. Mylan had more bupe etc. I called. Mylan pharmaceutical company today as a clinical tech pumping for info. Basically i was told they have 8mgs. of bupe. period. They are totally equivalent to brand as far as active bupe ingredient. Also to pass standerds they must have 90% mgs. I disagreed and filed a complaint leting them know the lot/batch didn't seem consistent. He agreed it could be a possibility so he gave my pharmacy info to research. I went to the source of course they may tell anyone anything but i dont like them or the surfboards or hi tech. Roxanes the most effective in my eyes. God bless

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26

Everybody has their own opinions, and just so you know the top two most favorite brands for Subutex are Roxane labs/big whites and high-tech/small whites.

Nobody likes Mylan. I really haven't met anybody that hasn't said that they prefer Roxane labs. It seems to be the #1 choice

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27

I've been doing tech for about three years now. I always get the 54-411 but I have gotten the M924 a couple of times. Both pills look identical except the imprint on them. Taste the same, feels the same. I see no difference except the life of the 54-411 seem to last in my system a little longer. I get mine filled at CVS and they always have 54-411. Ask your pharmacy which one they have before you get your pills filled, that's what I've done to make sure I get the ones I want.

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28

Okay, out of curiosity I decided to do back-to-back comparisons on the Mylan and the Roxane subutex pills. I transferred my remaining Rox. refill to a pharm. that carries only Mylan and here are my thoughts:

They are pretty much the same. Although from time to time there may be differences in one pill over another, I think they are almost identical right now. As I've mentioned in other posts, there are instances where a customer/patient may end up with a refill that contains a "mixed batch," i.e., the same generic manufacturer with pills that have varying amounts of buprenorphine, some of which may actually seem toxic. Recently I opened a bottle of Roxane generic subutex and the bottle actually seemed to emit fumes: a strong, medicinal odor that I have never before encountered.

Finally, in the past I have also tried the small ones (Acorn, Arrow, and others) and they are worthless. The pharmacist tried to tell me that the bioavailability in the small ones is actually greater than the amount of bup. in the larger pills. Still, when all is said and done, the best ones are no longer available at all, and that would be the Reckett original Subutex (the ones that were shaped, as someone else posted, like "surfboards."

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29

suffering 63-
I cant believe you were ever put on this medication (SUBS or Subutex) for pain. The fact that you have never struggled with addiction you should not have been put on this potent drug that your body cant function without. Not to mention how expensive this drug can be if you dont have insurance. It awful that you are in so much pain. Sounds like the Doctor you are going to failed you , BIG TIME. I really hope you werent going to a clinic(methadone or sub) to see this doctor bc those are the worst kind. You dont call those people doctors.. they are there to cram as many people in in the coupoe hours they are there .They write scripts all day, they dont listen. A family doctor or a pain managment place would be better than that.. Best of luck to you. Stay positive . Our words become our reality.

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30

I would like to know as well. Everyone keeps sayn from where I'm use to the 54 411 it's in my head but the m ones I would have to do more of.

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31

It's m924 bro it isn't m925 and I don't know I just got the m924 today have been for awhile now

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32

An RX coupon should get it down to about 160-170 at walmart

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33

Just curious, of why you don't like them cause that is what I picked up from pharmacy today. I don't need any side effects other than what I am used too....

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34

Okay, the reason I did not like the buprenorphine is very simple. I was having seizures almost every day on it and on top of that I wasn't sleeping at all I never went into rem because I used to remember my dreams, also killed my libido sorry but that's important when you've been married for 17 years. And it made me less sympathetic to people, I literally couldn't give a crap whether they lived or died and that's not who I am. I have been off it for over 2 months now and I am dreaming again and I am painting and writing again and everything is wonderful and the best part is no damn seizures at all. Now I know doctors are little overboard with the caution this these days about prescribing old fashioned opiates, but I have 4 ulcers icannot take aspirin or nsaids and I have been on opiates for 17 years and the buprenorphinee was the worst worst thing I ever put in my body. That being said a lot of people have said they like it that it works for them they don't have side effects and that's great for them. But for me I couldn't even drive my car because I was afraid I'd sieze behind the wheel. I guess it just depends on the person and their DNA and how they acclimate to certain medications. But if you notice that you're getting tremors those are side effects from buprenorphine.ne and you're headed for a major Grand Mall seizure that's how it hit me. I had to be hospitalized for 3 days in Virginia because of it. When your medicine makes you sicker than when you're not taking it you shouldn't be taking it.

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35

Daveliss, I want to thank you for your response. Wow!! Sezuire's that is horrible, are you prone to seizures? I have withdrawn from a long list of Medications and I guess I have been one of the lucky ppl that don't get seizures, at all... knock on wood....... So I totally know what you mean about the Libido thing, that is definitely out the window. I will be going away for a few years in a couple months, so this time when I get home from prison I will not use, not one single time... "Cause that's what I said to myself, oh April only tonight, then tonight turned into tomorrow, and so on, and on...... I do wish you the best and really appreciate your feedback.

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36

I know this message you posted may be old but no they did not stop making them, you just have to try other pharmacies. That's what I did.

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37

It is because the pharmacy's are having to pay more for the 54s and are getting the m ones cheaper I done figured it out samthing happend to me I really don't care anymore tho as long as I'm not sick

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38

I still have the 54 411 they haven't gone anywhere lol

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39

Re: DaveLis' post about the seizures he had after taking buprenorphine. That's a strange reaction to buprenorphine and it makes me wonder once again just what else these manufacturers are throwing into their "recipes."

In the past few months (give or take) I've noticed that the generic subutex made by Roxanne is different in that I can recall my dreams just as Dave mentioned in his post. I wasn't aware that this means you've not gone into the REM sleep stage, but I'm glad to know that.

I've always noticed that these pills have begun to make my mouth dry and my skin drier than usual (not cold-weather related), another reason to suspect they're mixing something else into the batches. This has never been a side effect I've experienced while taking this drug. Furthermore, the pills have a tendency now to make me more tired than usual, something I hadn't noticed before.

My suspicion is that some of the batches have been mixed with Benadryl (don't know the chemical name), hence the dry skin and the dreaming. Whenever I've taken Benadryl in the past I've had series of vivid dreams, not always the most pleasant and, needless to say, the dry skin/dry mouth can be a def. side effect of Benadryl considering it is an antihistamine. The tiredness is also a side effect of antihistamines.

Another time I had a batch of subutex generic that made me wonder if a benzo had been mixed into the ingredient list. I am very sensitive to benzos (hate them) with one of the side effects being that when they wear off my stomach begins to hurt very badly; well, this is the same reaction I had approx. 3 or 4 months ago. It wasn't just a week-long issue, either, which might have suggested I had a stomach virus or some other g.i. problem; this was definitely related to the drug itself.

They can put whatever the heck they want into this crap and call it whatever they want. As long as people buy it they're in the clear.
Incidentally, there's another thread that's been going on for a while on this website discussing problems with the Watson 325/10 hydro. (brand name: Norco). People are really worked up over the lack of efficacy in the recent batches being released.

The name of the thread is "New white Watson 853 10/325 problem - What is going on???!?" With so many people noticing something is amiss, I find it hard to believe that the problem is "all in their heads." Point is: It's not just the buprenorphine that's causing problems in its inconsistency.

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40

In Pennsylvania you can go from suboxone to subutex and vice versa. If you become pregnant while you are on suboxone the Dr will switch you to subutex. If you receive migraines you can be switched from suboxone to subutex. On the other side of things, if you are on subutex and are abusing opiates still the Dr. will switch from subutex to suboxone, or if you prefer the naloxone because of relapse scares you can go to suboxone from subutex. I know it's the same in Ohio and west Virginia as well. I don't see why you think it can't be done. They are the same drug with the only difference is suboxone has naloxone in it to prevent opiate abuse.

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