Doriden/glutethimide Availability

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Does anyone know where one could obtain glutethimide or it's brand name Doriden (CIBA Company)? Am in Canada where Doriden was discontinued in late 1980s and I was told Doriden discontinue was international. Perhaps there is now a generic form containing glutethimide available now as I would assume CIBA trademark rights would have by now expired. As the benzodiazapine replacement meds for Doriden are more addictive and dangerous (especially if mixing with alcohol & other drugs) it sure would be great to be able to go back to Doriden or glutethimide which were more effective and safer. A shame that the public was switched over to benzodiazipines (i.e. lorazapam, diazapam) when a better/safer product was available all in the name of profits and economics. Any help out there is most appreciated.

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Doriden (glutethimide) is discontinued worldwide. The US banned it in '93 because of the abuse of it together with codeine which produced a strong euphoric opiate type effect. They were known as "hits" on the street, a "one on one" which was one Doriden and one codeine # 4.

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2

Was one of my favorites! Just spoke with a girl who said her sister gets Doriden and is adamant about it, but I still have my doubts....She could be mistaken. I'm in Erie, PA where the combination was once very popular...The most common name for them were "Sets".

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3

No Glutethimide is currently manufactured anywhere in the world. Yes I am well aware of the Doriden/Codeine combination, it was pretty pleasant and euphoric. But as far as finding Doriden it would be like finding the holy Grail.

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4

They were also called 'loads'. Or Dores and 4's. Extremely addictive and consisted of one Doriden and two #4 codeine. It was great for pain relief.

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5

love love love!!! I was devastated when I heard they were going kaput!!! Would love to get my hands on em now!!! Willing to pay high cost!!!!!

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6

Yes I know Doriden (Glutethimide) was a good med but like I said they are not manufactured anywhere by any Pharmaceuticals company. Use of Doriden with Codeine was big in my area of NJ. Ciba manufactured Doriden at one time and the tablets were stamped CIBA on them. Anyway, together they produced a very long lasting euphoric blissful peaceful warm feeling type of effect somewhat comparable to opiates but much better. In the US the DEA practically forced the few manufacturers of Doriden (Halsey was one maker of generic Glutethimide) to cease and discontinue making them, that was in '93. They were available in Hungary, Romania and Bulgaria up until 2006, but couldn't be exported to any other countries. I think they were made by a company called Terapia Pharmaceuticals over there. Doriden was also available in them countries in combination with Amobarbital and Promethazine in a medication called Tardyl, used for insomnia. If that couldn't put you to sleep I don't know what else could. It contained 125mg of Doriden (Glutethimide), 50mg Amobarbital and I think 25mg Promethazine. A little overkill in my opinion. Like I said, finding some Doriden today would be like finding the holy grail. It's a dream of mine, but probably won't come true. To anyone who wants to learn more about how it worked I can explain in further detail. It has something to do with a liver enzyme that induces the codeine to convert to eighty to ninety percent morphine instead of the usual ten percent conversion. That combined with the sedative hypnotic effect of the Doriden made for something that was really special, to me anyway. Thank you.

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7

I had a few friends die because they fell asleep and drowned in their own vomit.

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Re: Joseph (# 1) Expand Referenced Message

Yes Joseph, we called them loads. They almost felt like life’s and even though I loved that stuff back in the day I’m grateful they are gone. I’m not sure where the OP got that Doridens are safer than Benzos. That would be funny if it wasn’t so scary.

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Re: Patrice (# 8) Expand Referenced Message

Yes Patrice, Doriden could be lethal. As for the Benzo family, the only way they can be lethal is if you choked on the pill trying to swallow it. I still have dreams about them occasionally. If you want to talk further about the chemistry of the interaction of Doriden with Codeine you can write me back.

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10

Like I stated previously, no Glutethimide is manufactured anywhere, sadly the DEA practically forced the last manufacturer in the US, Halsey Drug, who made the HD 550 tablets, to discontinue them. There was practically no legitimate use of Doriden by that time. The Benzo family of drugs superseded the use of Doriden, Noludar, Quaalude, Tuinal, etc... I too used Doriden and Codeine combination for about ten years, they were known as "Cibas and Codeine" in my area of New Jersey. Ciba manufactured Doriden in the beginning, in fact they synthesized it, and the tablets were stamped CIBA on them. They were very euphoric, blissful and long-lasting. I still dream about those days. They made you feel like you loved everyone, and everyone loved you. They also made you very social and talkative, when you were able to talk that is. And like I said before, they were used in a few eastern European countries until the early 2000's. Hungary, Romania and Bulgaria. The Glutethimide induced a liver enzyme that made the Codeine convert into 80 to 90% morphine instead of the usual 10%, then combined with the sedative-hypnotic effect of the Glutethimide and you had something special. There must be someone, somewhere with an old bottle of Doriden in their medicine cabinet. If kept cool and out of the light they can remain effective for quite a few years.

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Re: Joseph (# 10) Expand Referenced Message

Sorry for my English but in Hungary, Romania it's still available. Be kind and don't write bulls***.

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Re: Dusan (# 11) Expand Referenced Message

Really, in the Tardyl combination or 500 mg Glutethimide tablets? I will contact a travel agent to book a flight to Budapest as soon as possible.

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Re: Joseph (# 12) Expand Referenced Message

Under the brand name Noxyron by Richter Pharma are discontinued in Hungary As Far As I Know.

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Re: Dusan (# 11) Expand Referenced Message

What name is the drug under there and as the other guy ask is it doriden alone or mixed with barbituites? Cuz I wanna call his travel agent as well.passports ready or maybe just have them mailed. Thanks R

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Re: R (# 14) Expand Referenced Message

If Glutethimide is still available in Hungary, which I have heard many times over the years from many different sources, I don't think that they can be mailed to a different country, I'm in the US by the way, we would have to venture over to Hungary. They were made under the brand name Noxyron by Richter Geodon Pharma in Hungary, at least up until '06. I don't think the Tardyl combination with the Amobarbital and Promethazine is still available. That's a little overkill in my opinion. I am only interested in the Glutethimide (Doriden) 500 mg. tablet. The Tardyl combination tablet had two layers, first the Glutethimide was released, then you would fall asleep, then time released Amobarbital (Amytal was the brand name by Lilly) would kick in with the Promethazine (Phenergan) to keep you asleep through the night without waking up and having a hard time getting back to sleep. Anyway, Glutethimide was quite popular in my area of NJ, they were known as "hits", or "ciba and Codeine", because Ciba synthesized Glutethimide in the mid 50's and the tablets were stamped CIBA on them. In the 70's the rights were sold to the US Vitamin (USV) subsidiary of Rorer Pharmaceutical, which made the USV 354 white, round ,scored tablets. I remember a few generic Glutethimide manufacturers, Halsey Drug with their HD 550 tablet, Medeva and their MD 529, and Rugby Labs with their R 3870 tablets. There were several reasons why Glutethimide was discontinued in the US. But getting back to Hungary, are they still prescribed there? If I know for sure I will get my passport together and contact my local travel agency. Then there is the question of bringing any back to the US, legal questions, I don't want to break any laws. I used Glutethimide with codeine for about ten years or more. Very euphoric and pleasurable, nothing comes close to my Glutethimide and Codeine combination. Please let me know. Thanks.

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Re: R (# 14) Expand Referenced Message

The Tardyl combination was (or still is) made by Extractum Pharma of Hungary. Also, Hungry was a major importer of Glutethimide. I am only interested in the Glutethimide 500mg tablets, not the Tardyl combination of 125mg of Glutethimide, 50mg of Amobarbital (Amytal) and 25 mg of Promethazine (Phenergan). Please let us know of the availability of Glutethimide in Hungary and Romania, and I believe Bulgaria too.

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Re: Joseph (# 16) Expand Referenced Message

I've been reading your posts and my interest is definitely peaked regarding the availability of Glutethimide in Eastern Europe. Like you I still dream about them often and would love to experience them again. My original source dried up in 93 and then I discovered the internet in 99 and started getting them from Bulgaria until 2003. At that time the pharmacy went out of business and the source dried up. They had 250mg Glutethimide and 20mg Codeine phosphate. I don't have a passport but I'll get one real quick if I know they are available.

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Re: fred (# 17) Expand Referenced Message

I'm sorry to have to tell you this but according to Martindale the last year for Glutethimide in Hungary was '06, that is the year that Ranbaxy Pharma of India purchased Terapia Pharma of Hungary and discontinued their low selling medications and Glutethimide was one of them. There still may be a company called Balkanpharma of Bulgaria, I'm looking into it. You are a lucky man to have been getting them up til '03, I lost them in '93 here in the US, so you had 20 more years than me. When I get more info I will post it here, but it looks like the benzo family has replaced them, just like they replaced everything else that was good. One day I will be reunited with my beloved Glutethimide.

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Re: Joseph (# 18) Expand Referenced Message

I meant ten more years than me to have been getting Glutethimide not twenty.

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Re: Joseph (# 1) Expand Referenced Message

We called them loads because mixing codeine and doriden felt a lot like quaaludes

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132

Re: Joseph (# 1) Expand Referenced Message

Your are right Joseph. They were sold illicitly in manhattan. They would hit their fist together at the cars where people were looking. Very addictive.

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131

Re: Dusan (# 11) Expand Referenced Message

Is that still true now in 2023 ?

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130

Re: Ed (# 7) Expand Referenced Message

Several friends of mine as well.

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129

Re: Joseph (# 1) Expand Referenced Message

No, they were called "Loads" or "Doors and Fours".

You sound very confused and unfamiliar with the actual slang name of this drug.

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128

They were discontinued in the US I in "93. Doriden and codeine were very popular in my area.

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127

I am sorry to say that you'll probably will never find a Doriden tablet ever again in your lifetime. And they were so widely available at one time. Dors & Fours!

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126

Re: Fred (# 124) Expand Referenced Message

Soma (Carisprodol) is a CYPD26 liver enzyme inducer like Glutethimide and there is a Soma compound with codeine that's also made. It took the government about 40 years to make it a controlled substance, schedule 4. You see Carisprodol turns into the ancient sedative Meprobamate in your body. Meprobamate, which I don't even know if it's still made, was branded as Miltown, and Equanil. It was actually invented by Wyeth IIRC in their R&D labs in Miltown NJ! Anyway, I heard it's close but no cigar. Same thing with Promethazine with codeine syrup. Like I said previously I don't think we'll ever see a Glutethimide tablet ever again in our lifetime. I'm 99.99% sure. West Orange

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125

Re: Fred (# 124) Expand Referenced Message

No Fred it's not the same as aminoglutethimide. The DL stands for delimited, or inactive, usually sold in a very small amount in a milliliter of methanol. Used for research purposes, I don't know on what but I've seen it online before and it's of no value. I wish I could have better news but I don't think we will ever see them again, I'm sorry to say. As for the dark web, many scammers out there, and synthesis of Glutethimide is very complex as compared to the more simpler barbiturates. Try to keep in touch.

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124

Re: Joseph (# 123) Expand Referenced Message

Yes I'm aware of AminoGlutethimide but didn't realize it's one and the same as DL Glutethimide.

No, never been on dark web.

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123

Re: Fred (# 119) Expand Referenced Message

Forgot to mention that the breast cancer medication Cytadren name is Aminoglutethimide

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