Dexedrine: How Much Is Too Much?
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Is 30 mg of dexedrine (15x15) too much in one day?

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Re: HCStymie (# 6) Expand Referenced Message

with amphetamines there is a point of diminishing returns.

the exact dose varies from person to person. I consider 30mg a descent dose; 20 mg is too little these days.

when adderall first came out they where 25 mg tablets. 50 mg is high for me; 30 to 40 mg is a good dose for myself.

i am a male with a weigh of 190 at 5'7".

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Re: Wendy (# 3) Expand Referenced Message

Wendy, did you appeal the decision of the insurance company? Sometimes they just default to decline things and hope the subscriber doesn't bother to appeal (many don't which saves them money). One insurance I had did that to me once per year for Adderall, then I'd have to tell my doctor to contact the insurance and say it was the right dosage.

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5

the max dose used to be 60mg per day. the dex back then was _much_ stronger than the stuff nowadays.

For long days I used to extend the dose to 3x a day.

+ 1x wake
- food
+ 1x work
- lunch
+ 1x or .5x stat cleanup
- sleep

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4

The max recommended dose of spansules was around 60mg. Sometimes with a stat.

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3

What BS it is for anyone to tell you how much is too much. I was taking 100 mg of dexedrine for 17 years and then my health insurance cut me to 60 and it has been a struggle for me for the last 3 years. My first dr. was an ADD specialist and he let me decide what my body needed and I kept raising my dose until I got where I needed to be.. 100 mg. I do not have any additional problems, do not abuse medications, do not even drink alcohol and I was a functioning attorney. Now I am so much worse. No one has the right to tell us what we need to function if we are not having abuse problems, etc.

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2

30mg/day is not too much. The prescribed dose is not limited by fixed daily maximums but by the clinical judgment and willingness of your physician.

The 40mg/day and 60mg/day maximums for dextroamphetmine sulfate were established long ago and for ADHD in children. (At the time the "experts" established these maximums, the experts also said ADHD was purely a childhood disorder that was always outgrown.) When weight based dosing as used in children is applied to adults, the doses may exceed these maximums yet may produce better results.

This is called "off label" dosing.

Is more better? It depends on the individual. It should be guided by response and side effects.

Many psychiatrists who don't blink at pushing, say, mood stabilizers above FDA maximums will never dare this with stimulants. Hopefully in time this rigid attitude will change to best benefit patients.

In 1989 Davy & Rodgers said, "the ultimate dose should be as small as possible and as large as necessary to optimize the selected outcome.... Recommendations not to exceed a specific dose of stimulant medications should be avoided, since there is no basis in scientific evidence." A 1996 article by Kessler notes, "Popper has asserted that statements on package inserts [such as maximum dosages] are not intended to limit medical practice. Rather, they are intended to limit claims by pharmaceutical companies.... [C]linical decisions are to be made by physicians and patients in individual situations."

Practical advice... It's possible that you are experiencing troubling side effects. You can more slowly and gradually increase the dose. You will probably gradually become tolerant to side effects. Until then, for nausea, Emmetrol is helpful. For sleep, try taking the second dose earlier, take Vitamin C (drink OJ) in the evening as it increases elimination, or your doc can divide the dose between instant release and extended release or can give a low dose of an antipsychotic drug at bedtime for a few weeks. (You're not psychotic but this will block dopamine and let you sleep.) In the end, what is too much depends on your response.

You might find this site informative:
addclinician.wallyhood.org/medication/stimulants/stimulant-medications/prescribing-adult-doses-of-stimulants-for-adults

Two published articles quoted above: (PubMed abstracts)
ncbi.nlm.nih.gov/pubmed/2513337

ncbi.nlm.nih.gov/pubmed/8545689

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1

The maximum standard daily dose of it can go up to 40mgs and in rare cases 60mgs, where a higher dose is needed to treat certain severe conditions.

Learn more Dexedrine details here.

However, you should stick with whatever dose your doctor has prescribed. if it isn't working, then you should contact your doctor to discuss possible solutions.

Are there any other questions or comments?

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