Cosentyx And Hematuria (blood In Urine)

Diana J Says:

Hi, I’m a 43 year old female and have had psoriatic arthritis for 26 years now. I’ve been on several different treatments in the past and now taking Cosentyx since feb 2021. I started with the loading dose and now on 300mg fortnightly. I haven’t experienced any side effects yet, however the last 4 days have noticed blood in my urine with tiny clots. I had a urinalysis done and results were clear of infection except it showed high level of blood in urine. I also had a renal and pelvis ultrasound and the results were good.

My Dr has referred me to a urologist who I will see on 31st May. Back in 2004, while I was taking methotrexate I experience blood in urine and had a cystoscopy done. The results showed a malignant tumor in my bladder which was removed. I had no further treatment for this. My Dr says I’m at high risk of bladder cancer given my history. I was wondering if hematuria is a possible side effect of Cosentyx or if anyone has or is experiencing blood in urine while on cosentyx?

Your feedback is much appreciated. I’m very worried that it may be cancer and hoping it’s just a side effect.


2 Replies

Earliest Newest Votes
Roy Says:
Top Answer

Hi Diana,

The Mayo Clinic does list "bloody or cloudy urine" as one of the possible side effects of Cosentyx (Secukinumab):

" Check with your doctor immediately if any of the following side effects occur:

More common
- Bladder pain
- bloody or cloudy urine
- burning feeling in the chest or stomach
- difficult, burning, or painful urination
- fever
- frequent urge to urinate
- headache
- indigestion
- loss of appetite
- lower back or side pain
- muscle aches
- nausea or vomiting
- passing of gas
- rectal bleeding
- sore throat
- stomach pain, cramps, fullness, discomfort, tenderness, or upset
- stuffy or runny nose
- unusual tiredness or weakness
- watery or bloody diarrhea

Less common
- Body aches or pain
- chills
- cough or hoarseness
- difficulty with breathing or swallowing
- dryness of the throat
- ear congestion
- hives or welts, itching, or skin rash
- loss of voice or voice changes
- painful cold sores or blisters on the lips
- redness of the skin
- scaling of the skin
- sore mouth or tongue
- tender, swollen glands in neck
- white patches in the mouth or on the tongue

- Severe diarrhea
- weight loss

Incidence not known
- Dizziness
- fast heartbeat
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- tightness in the chest "

I hope this helps and best wishes!

Source: Secukinumab (Subcutaneous Route) Side Effects

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Diana Says:

Re: Roy (# 1) Expand Referenced Message

Hi Roy,

Thank you so much for your reply. I’m glad to hear that bloody urine is a possible side effect and hopefully this is the case. I am seeing my rheumatologist in a couple of days and will find out more when I see the urologist as well.

Thank you kindly,

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