Chornic Constipation

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I am suffering from chronic constipation for the last 30 years coupled with gas problem. I have possibly all available medicines like pan -40 mg, zintec-150 mg, Razo-20 mg, some laxatives etc but of little use. Is endoscopy the only option left in my case. Kindly advise me .

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I have suffered from chronic constipation and IBS for most of my adult life. Since my hysterectomy, and gall bladder surgery, my condition has worsened. I have been tested for Chron's Disease and that was negative. I was recently referred to a GI Specialist, who initially started me on Amitzia. I had very uncomfortable side effects, including abdominal cramping, diarrhea, and nausea. He then switched me to Linsza. When I take the Linsza, I honestly cannot get off of the toilet for several hours, due to constant diarrhea. My doctor has now prescribed Lactulose, but I am hesitant to try any other drugs because of the negative side effects Ive had thus far on the other drugs. My concern is that what if this is NOT the condition that needs to be treated. What if its something else? Ive had CT Scans in the past, and a colonoscopy which both turned up negative results. Im just confused as to where I should go from here. Do I get a 2nd opinion, or is all of this normal with IBS and Chronic Constipation?

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Vrijender, yes, I think you should pursue having the endoscopy/colonoscopy, to see if there is something else causing your issue, since none of the medications have worked.

Melissa, yes, those symptoms can be normal with chronic constipation and IBS. If your scans and the colonoscopy showed nothing, then the existing conditions are most likely the cause. Did you try the Lactulose, yet? It could be worth a short and you can always stop using it, if you have problems with it, too.

It can cause the same side effects you've experienced before, nausea, diarrhea, abdominal cramping and gas.

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I been constipated for almost a week the pharmacy said most is from medications such as thyroid meds nexuim and once a day nerve meds I am hurting all in my ribs under my feet as I walk I am so in need of advice and if I take a lot of Phillips milk of magnesia it helps for a day

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