Can Methotrexate Cause A False Positive For Cocaine?

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Bobbie Says:


I give myself weekly injections of 1cc of methotrexate. I got a false positive for cocaine. I have never used cocaine. Could the injection of methotrexate be the cause?



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David Says:

I'm not sure why, but there's little information available online regarding this. I only came across one link that has a good amount of information on the probability rate of Methotrexate causing a false positive. Maybe you can find some helpful information in there:
http:/­/­rheumatology.oxfordjournals.org/­content/­48/­6/­597.full

I would also suggest contacting the manufacturer of your medication to ask them about this situation. If it is in fact the drugs fault for your false positive, they should be able to write you a letter saying that this is the case (for future drug testing).

I hope this helps!

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