Hi - has anyone else heard about the research being done on Bexarotene as a viable Alzheimer's treatment? Apparently they have been testing it in mice and it appears to quickly and effectively stop (and even reverse) degeneration in the brain tissue.
They basically took mice which were genetically engineered to exhibit Alzheimer's symptoms (yeah, cruel, I know) and observed how their brains would get built up with amyloid beta peptides (which are basically thought to exist in excess as plaque in the brains of people suffering from Alzheimer's and it causes the blocking up of neurons and cell death). And of course the mice would exhibit some of the classic early signs such as forgetfulness.
Anyways, Scientific American has described some of the findings: "with just a single dose it lowered the most toxic form of the amyloid beta peptide by 25 percent within six hours, an effect that lasted for up to three days. Mice that were cognitively impaired by the amyloid buildup resumed normal behaviors after 72 hours: They began to crinkle toilet paper placed nearby to make nests, a skill lost as amyloid increased in their brains." 
Supposedly they should be starting human clinical trials in the next few months. I must say that this is pretty promising! My grandmother is in the late stages and it would have been nice if such a treatment could have existed for her 10 years ago. What does everybody think? Do you think that they will move forward and eventually offer this as a "cure" in the coming years?
 Scientific publication: http://www.sciencemag.org/content/early/2012/02/08/science.1217697
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