Afraid To Take Pristiq

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Y0ungshel Says:

I have been diagnosed with Fibromyalgia and Depression. I have been on many different meds and am feeling very frustrated about how things are not progressing. I had been hearing good things about Pristiq, so my Dr. gave me a month of samples. I have done some more reading and have some questions.

1. I read that it makes some people sleepy and some people have energy so when is the best time to take it?
2. Looking at the drug interactions, there are 188 major drug reactions, one of which is Adderall, and I am prescribed that too. Is anyone taking Adderall with Pristiq?
3. Is it really the same thing as Effexor?
Any help you could give would really be appreciated

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Heather Says:

I take Pristiq and Adderall along with a whole host of other things for Fibromyalgia and Depression. My doctor is a Medication Management physician and an psychiatrist and watches my meds very closely! I am also on morphine for extreme pain from the fibro and arthritis and migraines. I was on Effexor for many years. Is it the same? I don't know. But I feel much better on it. I have been on it for almost a year. One side effect I have noticed is severe weight gain! I have gained almost 35 pounds for absolutely no reason! All of my meds should make me lose weight, yet I continue to gain. I don't eat because I have no appetite! I am a 55 year old female and I am finally considered disabled.

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Verwon Says:

Pristiq contains the active ingredient Desvenlafaxine, it is an SSNRI antidepressant.

That said, it is related to, but not the same as Effexor, which contans Venlafaxine, though they do work in the same manner.

As to your other medications, does your doctor know you are also on Adderall? They do have to take all of your medical conditions and current medications under consideration when prescribing something new. I would advise following their instructions or talking to them about any concerns you may have.

All medications come with the risk of side effects, with this medication, you may experience: nausea, drowsness, dry mouth and weight gain.

As to when you should take it, did your doctor suggest any specific time of day?

You can read more on the medication here:


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Kat Says:

I have been taking pristiq for 6 weeks and have actually lost 15 lbs. I found that i also was very tired thru the day so i started taking it at night 2-3 hours before i went to bed and that made a Big difference for me. I no longer sleep thru the day and feel so much better all day long. The bad thing for me insurance wont pay for it so now i have to go to effexor. I hope you have good results. Try taking it at night for a few weeks.

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jeff Says:

Please DO NOT TAKE this med.
I took one pill 3 months ago and am still suffering the effects.
Please, please, please look to other (hopefully natural) remedies.
Good luck!!!

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JAN Says:

Itake pristiq 50mg I feel wonderful Ialso take6 others.Ipay $85 .my insur is AARP .it'sworth it.

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Mary Says:

I started Pristiq in April 2011. I feel like a now woman! I started to feel better within 1 week. It changed my life. I have lost 26# as well. I have really watched my food intake and I'm exercising more. My depression is gone. It does make me drowsy, so I take it before bedtime.

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Dumbfounded Says:

Really? Suffering effects from 1 pill 3 months later? Nah. No way. And besides, just because you had a reaction to it doesn't mean someone else will. All our bodies are different.

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