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100+ Topics FoundSimvastatin, sold under the brand name Zocor among others, is a lipid-lowering medication.[2] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels.[2] It is also used to decrease the risk of heart problems in those at high risk.[2] It is taken by mouth.[2] Common side effects include constipation, headaches, and nausea.[2] Serious side effects may include muscle breakdown, liver ...
Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953[1] and used as an antipruritic. During research and development, pramocaine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.[1] Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and ...
Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery.[4] It is also effective for treating gastroenteritis.[5][6] It can be given by mouth or by injection into a muscle or into a vein.[4] Common side effects include diarrhea, constipation, headache, sleepiness, and itchiness.[4] Serious side effe...
Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery.[4] It is also effective for treating gastroenteritis.[5][6] It can be given by mouth or by injection into a muscle or into a vein.[4] Common side effects include diarrhea, constipation, headache, sleepiness, and itchiness.[4] Serious side effe...
Hydrocodone (Dihydrocodeinone) is an opioid used to treat pain and as a cough suppressant.[9] It is taken by mouth.[9] Typically it is dispensed as the combination acetaminophen/hydrocodone or ibuprofen/hydrocodone for pain severe enough to require an opioid[10][11] and in combination with homatropine methylbromide to relieve cough.[9] It is also available by itself in a long-acting form under the brand name Zohyd...
Lonafarnib, sold under the brand name Zokinvy, is a medication used to reduce the risk of death due to Hutchinson-Gilford progeria syndrome and for the treatment of certain processing-deficient progeroid laminopathies in people one year of age and older.[2][3] The most common side effects included nausea vomiting, headache ,diarrhea, infection, decreased appetite and fatigue.[2] Lonafarnib was approved for medical use in the United States in Nov...
Goserelin, sold under the brand name Zoladex among others, is a medication which is used to suppress production of the sex hormones (testosterone and estrogen), particularly in the treatment of breast and prostate cancer.[1][2] It is an injectable gonadotropin releasing hormone agonist (GnRH agonist). Structurally, it is a decapeptide. It is the natural GnRH decapeptide with two substitutions to inhibit rapid degradation. Goserelin stimulates the production of ...
Zoledronic acid, also known as zoledronate and sold under the brand name Zometa[4] by Novartis among others, is a medication used to treat a number of bone diseases.[3] These include osteoporosis, high blood calcium due to cancer, bone breakdown due to cancer, Paget’s disease of bone[3] and Duchenne muscular dystrophy (DMD). It is given by injection into a vein.[3] Common side effects include fever, joint pain, high blood ...
Zoledronic acid, also known as zoledronate and sold under the brand name Zometa[4] by Novartis among others, is a medication used to treat a number of bone diseases.[3] These include osteoporosis, high blood calcium due to cancer, bone breakdown due to cancer, Paget’s disease of bone[3] and Duchenne muscular dystrophy (DMD). It is given by injection into a vein.[3] Common side effects include fever, joint pain, high blood ...
Zotepine is an atypical antipsychotic drug indicated for acute and chronic schizophrenia. It has been used in Germany since 1990 (although it has been discontinued in Germany) and Japan since 1982. Zotepine is not approved for use in the United States, United Kingdom, Australia, Canada or New Zealand.[2] Contents 1 Medical uses 2 Side effects 3 Pharmacology 3.1 Pharmacodynamics 4 Society and culture 4.1 Brand names 5 See also 6 References 7 Further reading Medical...
Vorinostat (rINN)[3] also known as Suberoylanilide hydroxamic acid (suberoyl+anilide+hydroxamic acid abbreviated as SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a broad spectrum of epigenetic activities. Vorinostat is marketed under the name Zolinza (/zolnz/ zoh-LIN-z) by Merck for the treatment of cutaneous manifestations in patients with cutaneous T cell lymphoma (CTCL) when the disease...
Zolmitriptan, sold under the brand name Zomig among others, is a triptan used in the acute treatment of migraine attacks with or without aura and cluster headaches. It is a selective serotonin receptor agonist of the 1B and 1D subtypes. It was patented in 1990 and approved for medical use in 1997.[1] Contents 1 Medical uses 2 Adverse reactions 3 Contraindications 4 Mechanism of action 4.1 Pharmacokinetics 5 Economics 5.1 Brand names 5.2 Economics 6 Legal status 7 Refer...
Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.[9] The efficacy of sertraline for depression is similar to that of other antidepressants, and the differences are mostly confined to side effects. Sertraline is better tolerated than the older tricyclic antidepressants, and it may work better than fluoxetine for some subtypes of depression. Sertraline is effective for panic disorder, socia...
Zolpidem, sold under the brand name Ambien, among others, is a medication primarily used for the short-term treatment of sleeping problems.[7][8] Guidelines recommend that it be used only after cognitive behavioral therapy for insomnia and behavioral changes, such as sleep hygiene, have been tried.[9][10][11] It decreases the time to sleep onset by about fifteen minutes and at larger doses helps people stay asleep...
Zolpidem, sold under the brand name Ambien, among others, is a medication primarily used for the short-term treatment of sleeping problems.[7][8] Guidelines recommend that it be used only after cognitive behavioral therapy for insomnia and behavioral changes, such as sleep hygiene, have been tried.[9][10][11] It decreases the time to sleep onset by about fifteen minutes and at larger doses helps people stay asleep...
Iloperidone, commonly known as Fanapt and previously known as Zomaril, is an atypical antipsychotic for the treatment of schizophrenia. Contents 1 Medical uses 2 Side effects 2.1 Discontinuation 3 Pharmacology 4 Regulatory approval 5 See also 6 References 7 External links Medical uses Iloperidone is indicated for the treatment of schizophrenia. In a 2013 study in a comparison of 15 antipsychotic drugs in effectivity in treating schizophrenic symptoms, iloperidone demonstrated mild ...
Zomepirac is an orally effective nonsteroidal anti-inflammatory drug (NSAID) that has antipyretic actions. It was developed by McNeil Pharmaceutical, approved by the FDA in 1980, and sold as the sodium salt zomepirac sodium, under the brand name Zomax. Due to its clinical effectiveness, it was preferred by doctors in many situations and obtained a large share of the analgesics market; however, it was subsequently withdrawn in March 1983 due to its tendency to cause serious anaphylaxis in a s...
Zomepirac is an orally effective nonsteroidal anti-inflammatory drug (NSAID) that has antipyretic actions. It was developed by McNeil Pharmaceutical, approved by the FDA in 1980, and sold as the sodium salt zomepirac sodium, under the brand name Zomax. Due to its clinical effectiveness, it was preferred by doctors in many situations and obtained a large share of the analgesics market; however, it was subsequently withdrawn in March 1983 due to its tendency to cause serious anaphylaxis in a s...
Zoledronic acid, also known as zoledronate and sold under the brand name Zometa[4] by Novartis among others, is a medication used to treat a number of bone diseases.[3] These include osteoporosis, high blood calcium due to cancer, bone breakdown due to cancer, Paget’s disease of bone[3] and Duchenne muscular dystrophy (DMD). It is given by injection into a vein.[3] Common side effects include fever, joint pain, high blood ...
Zolmitriptan, sold under the brand name Zomig among others, is a triptan used in the acute treatment of migraine attacks with or without aura and cluster headaches. It is a selective serotonin receptor agonist of the 1B and 1D subtypes. It was patented in 1990 and approved for medical use in 1997.[1] Contents 1 Medical uses 2 Adverse reactions 3 Contraindications 4 Mechanism of action 4.1 Pharmacokinetics 5 Economics 5.1 Brand names 5.2 Economics 6 Legal status 7 Refer...