What Is In Linzess

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Linzess was prescribed by my pcp, 1 capsule every other day for oic. It works within about 4 to 5 hrs and works just fine, no sidefects what so ever. The medicine works just fine for OIC. So whatever you people are experiencing has got to be a fluke, the medicine works just fine. ## We are all different, so a medication that works well for you may not work great for someone else that tries it. Have you experienced any side effects, such as nausea, dizziness, bloating, diarrhea, and abdominal pain that the FDA lists as being common with this medication?

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Linzess Linaclotide

Linaclotide, (sold under the brand name Linzess in the US and Mexico, and as Constella elsewhere)[2] is a drug used to treat irritable bowel syndrome with constipation and chronic constipation with no known cause.[3][4] It has a black box warning about the risk of serious dehydration in children in the US; the most common adverse effects in others are gastrointestinal.[3] It is an oligo-peptide agonist of guanylate cyclase 2C and...

Chronic constipation with 40-50 lbs weight gain... Linzess works with explosive diarrhea within an hour of taking it but doesn't seem to resolve the problem. It makes me go from feeling 9 months pregnant to 6 months pregnant. Also have a new side effect of the drug (or the constipation) which is acne on my shoulders and back. Tries lots of otc remedies and natural remedies with no luck. Dr gave me linzess and like I said it works but not completely. The 145 dose seems to work while the 290 did not, so i went back to 145 and same results. I am fit. Used to do 1000 sit ups a day...now can't manage 20 due to the bloat and weight gain...frustrated and worried. I am a big guy...6'7"...should be 230# but am weighing in at about 280# which has been increasing over the past 6-7 ...

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Taking linzess for two weeks. I feel great. No more bloating. No side effects, although do make sure you take it 30mins before your first meal of the day or you could have some of the side effects worsen. ## Taking it closer to a meal could also result in it not being as effective. The FDA lists the typical side effects of this medication as possibly including nausea, dizziness, bloating and diarrhea. Is it still working well for you? ## Hi, I've had terrible bloating along with the constipation for a while and I started up on lizness about 4 days ago. I was curious if you had bloating when starting out and then it got better after the 2 weeks or was it just good since you started? (Sorry for writing so much)

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I have been on linzess for a week now and no results yet besides bad bloating! Will the bloating go away? How long does it normally take to start working? ## How are you feeling? Have your symptoms improved any? It can take several weeks for a medication to reach its full efficacy level in your body and for the side effects to peak and begin to taper off, usually 4 to 6 weeks. ## I started linzess a few days before a colonoscopy and it worked. Now five days after the colonoscopy it hasn't worked yet. I have ibs c. ## I just took a bisacodyl laxative 2 days ago, I had a BM the first day but nothing since. My doctor gave me 290 mcg Linzess to take. Is it safe to take it 2 days after the bisacodyl laxative or should I wait a few more days? ## If I'm unable to take Linzess before br...

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I have tried taking Linzess as needed and everyday. My experience was more often used less lt will works. Taking a break from your Linzess just for one day can make it work better. But need to use fiber drink or stool softener in place of . Do not eat bananas or any food that will cause constipation. Drink 100% pure apple juice and orange juice high pulp and fresh oranges . Also eat activia yogurts with fiber one everyday will help . ## I would think that the fiber in fruit like bananas would promote regular bowel movements (as they have in my experience), but I know we are all different. Dried prunes or dates also reportedly aid in GI tract motility; and probiotics are another thing that may be worth implementing. I suppose there is no one right way to make things flow more easily, but...

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I started taking the low dose now I take too of them a day...only had one bowel movement when I started ...don't know what to do not #help ## Hello, Terri! How are you? Are you making sure to take it in the morning, with a full 8 ounce glass of water, at least a half hour, before eating or drinking anything else? It seems that some people weren't told that by their doctor or pharmacist. The FDA lists its typical side effects as possibly including nausea, bloating and diarrhea. ## Exactly right. That is how my doctor instructed me and it works, usually within an hour. ## Hi Terri, Linzess stopped working for me as well after about a year. One thing that did help me while on it was after taking it in the morning with a big glass of water, I would waite about 15 mins and drink a 6 ...

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I have gastroparesis and have been on Linzess for a year and a half. It worked ok until recently. Now I'm not going at all. Can I drink water the 30 minutes before my first meal. Most of the time I don't eat much. ## Hello, Donna! How are you? I'm very sorry about the problem you're having. It works best taken on an empty stomach, with just a sip of water. Typical side effects, as listed by the FDA may include nausea, dizziness, diarrhea and stomach pain. At this point, it would be best to consult your doctor, many people have reported a similar issue. For some people it only works for a few weeks, but sometimes it works longer, but few are having long-term good luck with it Are there any other questions or concerns? ## Thanks for replying. It is now giving diarrhea and ...

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I have Gastroparesis, pelvic floor dysnersia, and chronic ideopathic constipation. I had been taking 4 capfuls of miralax daily (which stopped working), amitiza (never worked) and now Linzess. The very first day it caused severe pain and I had pretty severe diarrhea. The next few days & nights I had severe abdominal pain, but now just cramping and lots of bloating. I have not had ANY movements at all since the diarhea on day 1. Is this normal? ## I hope your seeing a gastroenterologist and if so CALL the doctor. ## Hi GPcrusader, Sorry to hear about your situation. From what I've read on other related threads, the time it takes for Linzess to work actually varies greatly for each and every individual. However, I do agree with Amber in that it might be a good idea to touch base w...

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I've been on Linzess for constipation for two weeks. While it has only produced one bowel movement during this time, I was still hopeful. However, I woke up on a Wednesday with a swollen face and a bump in my eyebrow. I thought I had gotten bitten by something and didn't attribute it to the Linzess. Took Benadryl but didn't get any relief. I woke up with my eyes swollen almost shut on both Thursday and Friday morning and the bump in my eyebrow began to itch. By Saturday morning when I awoke to a swollen face and eyes again, I knew it was the Linzess. I am bummed since I was so hopeful that the Linzess would help me with my constipation. ## Oh wow! I am so very sorry about what happened. Did you consult your doctor? Has swelling gone away, yet? It is always possible to find o...

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When I take linzess with food it gives me severe diarrhea Will this be sufficient to clear me out for a colonoscopy ? ## Hello, Jen! How are you? It would be best to double check with your doctor. Sometimes that doesn't fully cleanse, so something else may still be required. Other side effects of Linzess, as listed by the FDA, may possibly include nausea, dizziness, bloating and flatulence. Is there anything else I can help with? ## It's best to take Linzess 30 mins to an hour prior a meal and not with food, as directed by the label. My friend is a pharm rep for it and he says this is important. When I first started taking it I thought alternating days would help but he said it's important to take it every day and that eventually the severe diarrhea should subside. He was ri...

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I have been taking Linzess for over a month now, highest dose. Have had IBS my whole life. I drink water all day long. I am peeing about every hour! I still have 4-5 days without a bowel movement then constipation followed by diarrhea. When I am able to have a bowel movement for a few days in a row, I feel so much pressure in my abdomen, like I have gas or have to go to the bathroom but can not go. I am so much more uncomfortable than before I started taking linzess. Has anyone else experienced this. ## Hello, Cindy! How are you doing? I am sorry about what you've been going through, but no you are not the first person to experience these issues. The gas, and abdominal pressure, can be normal side effects of this medication, according to FDA reports. You may also continue to experie...

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I was diagnosed with impacted bowels today and prescribed 290 mcg of Linzess. My pcp indicated this would get my bowels cleaned out (that I would basically have diarrhea until I am cleaned out) and then I will use it for maintaining good bowel movements. I am wondering how long it will take for it to start working for the cleanout as I need to go back to work but can't until I get this process over. ## Hello, Rena! How are you doing? It has passed the same FDA panel for approval as other medications used for the same or similar conditions. However, the only way to see if it will work for you is by actually trying it. Have you started it, yet?

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I have other prescription meds.. I take them in the mourning. Is it ok to take lizness with them together? I just worry about linzess flushing my meds out of my body before they work. Thank you. ## Hello, Lee! How are you? Unless your doctor instructs otherwise, you should take the Linzess at least a half an hour before eating or taking other medications. The FDA lists its typical side effects as possibly including nausea, dizziness, headache, bloating and diarrhea. What other medications are you on?

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I see you didn't get any answers I was just wondering how long you taking linzess and did you get ahead of the parasite issues? I'm having a lot of gastrointestinal issues in the doctors don't seem to care that I didn't have proof that I have parasites. Let me know if you can how things worked out with taking linzess and getting ahead of parasites. ## Hello, Tova! How are you? Since you didn't post this in response to a specific post, I am afraid I have to ask you for clarity. What parasite issues were you referring to? Linzess is most commonly used to chronic constipation and the FDA lists its typical side effects as possibly including nausea, dizziness, stomach cramps, and diarrhea. ## Sorry I thought I had posted this specifically to someone who would talked about...

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I was on the 290mcg Linzess and the diarrhea and abdominal pain was unbearable. Doctor has since switched me to Trulance which just came out. Having regular bowel movements with no pain or diarrhea. Doesn't need to be taken with food either. I have fought this for years and for the first time in a long time it's manageable.

Filed under Linzess

on 3rd day. Have bm' s in morning about 45/60 mins after taking Linzess. Those are only ones for the day. They are easier and formed. After I feel really good until afternoon when the bloating comes and feel full in bowel. Taking Gas X seems to help. When does full effect of Linzess happen? If IBS-C is the reason is this a 24/7 365 day or will there be periods of relief? Don't want to be on meds forever!!! Does it get better??? This is my first episode and it's been a month. 64 years old, would have thought it would have started when I was younger! ## Hello, Dot! How are you? It may take a couple weeks for it to reach its full level of efficacy in your body, but most people do have some results similar to yours early on. As listed by the FDA, other side effects may possibly ...

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I have a back problem and am taking pain meds that constipated me. Filling up until impaction and then blasting it out with potassium citrate, etc. Under the Doctor's guidance I reduced the pain meds and started Linzess. I did a clean out and then started the Linzess 3 days ago. So far nothing, no BM. I am on the 145 dosage. How long does it take this medication to work? I am taking it on an empty stomach at least 30 minutes before breakfast. ## Hello, John! How are you? Usually, people see results with first dosing. Are you taking it with water? You may need to try to higher dose. The FDA lists the typical side effects of this medication as possibly including nausea, dizziness, weight loss, bloating and diarrhea.

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I have been taking Amitza for about 4 months. Works great but over time getting extremely tired and sharp pains throughout body. I'm in process of trying to loose weight as well giving up dairy,red meats, and carbs. Switched to linzess three days ago. Reading posts that worry me about weight gain. Can you clear up the subject on weight gain and which drug works best? I've had issues for 19 years and tried everything. These medications both work for me but I need to have energy, no sharp pains and no weight gain. ## I added a multi-vitamin and b-12 supplement to help with energy. So far I'm doing okay. Been on Linzess for a week. It only started to work for me yesterday. Best of luck to you! ## @Kgirl, Posted below is a link to another active discussion thread here relating t...

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I've been taking linzess for a week and am having a lot of pain down low in my stomach. I had to take two aspirins to at least get some sleep one night. It also hurts when I urinate. I have to take it in the afternoon because I work during the day. It has been relieving me quite well. I'm just worried about having so much pain to where I moan and groan when I walk and I can't continue any kind of work out. Does anyone have a lot of gas with linzess? Sometimes it won't stop. If so, what helps you with this problem? ## Hi Jo, sorry to hear about your discomfort with Linzess. What mg are you taking? If on the 190 you may need to go to 145. I took Linzess for years and it was great. Took at bedtime and went 1st thing in morning. I will say you need to eat healthy diet. I wou...

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