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Meropenem + Vaborbactam

Vaborbactam (INN)[1] is a non-β-lactam β-lactamase inhibitor discovered by Rempex Pharmaceuticals, a subsidiary of The Medicines Company. While not effective as an antibiotic by itself, it restores potency to existing antibiotics by inhibiting the β-lactamase enzymes that would otherwise degrade them. When combined with an appropriate antibiotic it can be used for the treatment of gram-negative bacterial infections.[2] In the United States, the c...

Faricimab-svoa

Faricimab, sold under the brand name Vabysmo, is a monoclonal antibody used for the treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME).[1][2] Faricimab is the first bispecific monoclonal antibody,[3] to target both vascular endothelial growth factor (VEGF),[1] and angiopoietin 2 (Ang-2) inhibitor.[1] By targeting these pathways, faricimab stabilizes blood vessels in t...

Drug Category

Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual's immune system to develop adaptive immunity to a pathogen. Vaccines can prevent or ameliorate morbidity from infection. The effectiveness of vaccination has been widely studied and verified; for example, the influenza vaccine,[1] the HPV vaccine,[2] and the chicken pox vaccine.[3] Vaccination is the most effective method of preventing infectious diseases;[4] widespread immunity due to vaccination i...

Drug Category

Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual's immune system to develop adaptive immunity to a pathogen. Vaccines can prevent or ameliorate morbidity from infection. The effectiveness of vaccination has been widely studied and verified; for example, the influenza vaccine,[1] the HPV vaccine,[2] and the chicken pox vaccine.[3] Vaccination is the most effective method of preventing infectious diseases;[4] widespread immunity due to vaccination i...

Drug Index

Vaccinia virus (VACV or VV) is a large, complex, enveloped virus belonging to the poxvirus family.[2] It has a linear, double-stranded DNA genome approximately 190 kbp in length, which encodes approximately 250 genes. The dimensions of the virion are roughly 360 × 270 × 250nm, with a mass of approximately 5–10 fg.[3] The vaccinia virus is the source of the modern smallpox vaccine, which the World Health Organisation used to eradicate smallpox in...

Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female-associated pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, ute...

Tripelennamine

Tripelennamine, sold under the brand name Pyribenzamine by Novartis, is a drug that is used as an antipruritic and first-generation antihistamine. It can be used in the treatment of asthma, hay fever, rhinitis, and urticaria, but is now less common as it has been replaced by newer antihistamines. The drug was patented at CIBA, which merged with Geigy into Ciba-Geigy, and eventually becoming Novartis. Contents 1 Medical uses 2 Side effects 3 Pharmacology 3.1 Pharmacodynamics 3.2 Pharmacoki...

Tioconazole

Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer, now Johnson & Johnson). Tioconazole ointments serve to treat women's vaginal yeast infections.[1] They are available in one day doses, as opposed to the 7-day treatments more common in use in the past. Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athle...

Sulfanilamide

Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group.[1] Powdered sulfanilamide was used by the Allies in World War II to reduce infection rates and contributed to a dramatic reduction in mortality rates compared to previous wars.[2][3] Sulfanilamide is rarely if ever used systemically due to toxicity and because more...

Drug Index

Valaciclovir, also spelled valacyclovir, is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles).[1] It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases.[1] It is taken by mouth.[1] Common side effects include headache and vomiting.[1] Severe side effects may include kidney problems.[1] Use in pregnancy appears to be safe.[1&a...

Drug Index

Valbenazine, sold under the trade name Ingrezza, is a medication used to treat tardive dyskinesia.[1] It acts as a vesicular monoamine transporter 2 (VMAT2) inhibitor.[2] Contents 1 Medical use 2 Contraindications 3 Adverse effects 4 Pharmacology 4.1 Mechanism of action 4.2 Pharmacokinetics 5 Society and culture 5.1 Commercial aspects 5.2 Intellectual property 5.3 Names 6 Research 7 References Medical use Valbenazine is used to treat tardive dyski...

Mechlorethamine

Chlormethine (INN, BAN), also known as mechlorethamine (USAN, USP), mustine, HN2, and (in post-Soviet states) embikhin (), is a nitrogen mustard sold under the brand name Mustargen among others. It is the prototype of alkylating agents, a group of anticancer chemotherapeutic drugs. It works by binding to DNA, crosslinking two strands and preventing cell duplication. It binds to the N7 nitrogen on the DNA base guanine. As the chemical is a blister agent, its use is strongly restricted within t...

Valganciclovir

Valganciclovir, sold under the brand name Valcyte among others, is an antiviral medication used to treat cytomegalovirus (CMV) infection in those with HIV/AIDS or following organ transplant.[2] It is often used long term as it only suppresses rather than cures the infection.[2] Valganciclovir is taken by mouth.[2] Common side effects include abdominal pain, headaches, trouble sleeping, nausea, fever, and low blood cell counts.[2]...

Drug Index

Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a selective cyclooxygenase-2 inhibitor. It was patented in 1995.[1] Valdecoxib was manufactured and marketed under the brand name Bextra by G. D. Searle & Company as an anti-inflammatory arthritis drug.[2] It was approved by the United States Food and Drug Administration on November...

Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female-associated pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, ute...

Drug Index

Valerian (Valeriana officinalis, Caprifoliaceae) is a perennial flowering plant native to Europe and Asia.[1] In the summer when the mature plant may have a height of 1.5 metres (5 feet), it bears sweetly scented pink or white flowers that attract many fly species, especially hoverflies of the genus Eristalis.[2] It is consumed as food by the larvae of some Lepidoptera (butterfly and moth) species, including the grey pug. Crude extract of valerian root may have...

Estradiol + Testosterone

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female-associated pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, ute...

Drug Index

Valganciclovir, sold under the brand name Valcyte among others, is an antiviral medication used to treat cytomegalovirus (CMV) infection in those with HIV/AIDS or following organ transplant.[2] It is often used long term as it only suppresses rather than cures the infection.[2] Valganciclovir is taken by mouth.[2] Common side effects include abdominal pain, headaches, trouble sleeping, nausea, fever, and low blood cell counts.[2]...

Betamethasone

Betamethasone is a steroid medication.[3] It is used for a number of diseases including rheumatic disorders such as rheumatoid arthritis and systemic lupus erythematosus, skin diseases such as dermatitis and psoriasis, allergic conditions such as asthma and angioedema, preterm labor to speed the development of the baby's lungs, Crohn's disease, cancers such as leukemia, and along with fludrocortisone for adrenocortical insufficiency, among others.[3] It can be ...

Diazepam

Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic.[9] It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, benzodiazepine withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome.[9] It may also be used to cause memory loss during certain medical procedures.[10][11] It can be taken by mouth, inserted in...