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Tobramycin

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas.[5] It was patented in 1965, and approved for medical use in 1974.[6] It is on the World Health Organization's List of Essential Medicines.[7] Contents 1 Medical uses 1.1 Spectrum of susceptibility 2 Contr...

Tobramycin

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas.[5] It was patented in 1965, and approved for medical use in 1974.[6] It is on the World Health Organization's List of Essential Medicines.[7] Contents 1 Medical uses 1.1 Spectrum of susceptibility 2 Contr...

Dexamethasone + Tobramycin

Tobramycin/dexamethasone, sold under the brand name Tobradex, is a fixed-dose combination medication in the form of eye drops and eye ointment, marketed by Alcon.[1][2][3] The active ingredients are tobramycin (an antibiotic) and dexamethasone (a corticosteroid).[2] It is prescribed for the treatment of pink eye in combination with bacterial infections.[2] Contents 1 Contraindications 2 Side effects 3 Interactio...

Tobramycin + Dexamethasone

Tobramycin/dexamethasone, sold under the brand name Tobradex, is a fixed-dose combination medication in the form of eye drops and eye ointment, marketed by Alcon.[1][2][3] The active ingredients are tobramycin (an antibiotic) and dexamethasone (a corticosteroid).[2] It is prescribed for the treatment of pink eye in combination with bacterial infections.[2] Contents 1 Contraindications 2 Side effects 3 Interactio...

Drug Index

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas.[5] It was patented in 1965, and approved for medical use in 1974.[6] It is on the World Health Organization's List of Essential Medicines.[7] Contents 1 Medical uses 1.1 Spectrum of susceptibility 2 Contr...

Tobramycin Sulfate

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas.[5] It was patented in 1965, and approved for medical use in 1974.[6] It is on the World Health Organization's List of Essential Medicines.[7] Contents 1 Medical uses 1.1 Spectrum of susceptibility 2 Contr...

Drug Index

Tobramycin/dexamethasone, sold under the brand name Tobradex, is a fixed-dose combination medication in the form of eye drops and eye ointment, marketed by Alcon.[1][2][3] The active ingredients are tobramycin (an antibiotic) and dexamethasone (a corticosteroid).[2] It is prescribed for the treatment of pink eye in combination with bacterial infections.[2] Contents 1 Contraindications 2 Side effects 3 Interactio...

Tobramycin

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas.[5] It was patented in 1965, and approved for medical use in 1974.[6] It is on the World Health Organization's List of Essential Medicines.[7] Contents 1 Medical uses 1.1 Spectrum of susceptibility 2 Contr...

Drug Index

Tocainide (Tonocard) is a class Ib antiarrhythmic agent. It is no longer sold in the United States. Contents 1 Pharmacokinetics 2 Synthesis 3 References 4 Further reading 5 External links Pharmacokinetics Tocainide is a lidocaine analog, that does not have significant 1st pass metabolism. It is found in two enantiomers. The R isomer is 4x as potent as the S. Oral bioavailability is 0.9-1.0. In the blood tocainide is 10-20% protein bound. The Volume of distribution is 2.5-3.5 L/kg. ...

Drug Index

Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and pros...

Nonoxynol-9

Nonoxynol-9, sometimes abbreviated as N-9, is an organic compound that is used as a surfactant. It is a member of the nonoxynol family of nonionic surfactants. N-9 and related compounds are ingredients in various cleaning and cosmetic products. It is widely used in contraceptives for its spermicidal properties. Contents 1 Uses 1.1 Spermicide 1.2 Lubricant 1.3 Condoms 1.4 Cervical barriers 1.5 Shaving cream 1.6 Sports cream 1.7 Poison ivy creams 2 Side effects 3 References 4 External ...

Drug Index

Tofacitinib, sold under the brand Xeljanz among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.[4][5][6][7] Common side effects include diarrhea, headache, and high blood pressure.[6] Serious side effects may include infections, cancer, and pulmonary embolism.[6][8] In 2019, the safety committee of the European Medicines Agenc...

Tocilizumab-bavi

Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and pros...

Imipramine

Imipramine, sold under the brand name Tofranil, among others, is a tricyclic antidepressant (TCA) mainly used in the treatment of depression. It is also effective in treating anxiety and panic disorder. The drug is also used to treat bedwetting. Imipramine is taken by mouth. Common side effects of imipramine include dry mouth, drowsiness, dizziness, low blood pressure, rapid heart rate, urinary retention, and electrocardiogram changes. Overdose of the medication can result in death. Imipramin...

Fluorouracil

Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer.[2] By intravenous injection it is used for treatment of colorectal cancer, oesophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer.[2] As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts.[3][4] Side effects of use by injection are common.&...

Drug Index

Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes. It is part of the sulfonylurea family (ATC A10BB). Synthesis Tolazemide synthesis:[1] U.S. Patent 3,063,903 .mw-parser-output .citation{word-wrap:break-word}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}GB 887886 DE 1196200 para-Toluenesulfonamide is converted to its carbamate with ethyl chloroformate in the presence of a base. Heating that intermediate with...

Drug Index

Tolbutamide is a first-generation potassium channel blocker, sulfonylurea oral hypoglycemic medication. This drug may be used in the management of type 2 diabetes if diet alone is not effective. Tolbutamide stimulates the secretion of insulin by the pancreas. It is not routinely used due to a higher incidence of adverse effects compared to newer, second-generation sulfonylureas, such as Glibenclamide. It generally has a short duration of action due to its rapid metabolism, so is safe for use ...

Drug Index

Tolcapone, sold under the brand name Tasmar, is a medication used to treat Parkinson's disease (PD). It is a selective, potent and reversible nitrocatechol-type inhibitor of the enzyme catechol-O-methyltransferase (COMT).[1] It has demonstrated significant liver toxicity, which has led to suspension of marketing authorisations in a number of countries. In comparison with entacapone, another nitrocatechol COMT inhibitor, tolcapone has a longer half life (2.9 hours vs. 0.8 hour...