T V

Drug Index

Tavaborole, sold under the brand name Kerydin, is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed. Tavaborole was approved by the US FDA in July 2014.[1] The medication inhibits an essential fungal enzyme, leucyl-tRNA synthetase, that is required for protein synthesis. The inhibition of protein synthesis leads to termination of cell growth and then cell death, eliminating the fungal infection. Contents 1 Medical...

Fostamatinib

Fostamatinib, sold under the brand names Tavalisse and Tavlesse, is a tyrosine kinase inhibitor medication for the treatment of chronic immune thrombocytopenia (ITP).[1][2] The drug is administered by mouth.[1][2] Fostamatinib blocks the activity of the enzyme spleen tyrosine kinase (SYK).[2] This enzyme is involved in stimulating parts of the immune system.[2] By blocking SYK's activity, fostamati...

Clemastine

Clemastine, also known as meclastin, is a first-generation H1 histamine antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects.[1] Like all first-generation antihistamines, it is sedating.[2][3] Patented in 1960, it came into medical use in 1967.[4] Contents 1 Medical uses 2 Side effects 3 Pharmacology 4 Mechanism of action 5 Society and culture 6 References 7 External links Medical...

Acetaminophen + Clemastine + Pseudoephedrine

Clemastine, also known as meclastin, is a first-generation H1 histamine antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects.[1] Like all first-generation antihistamines, it is sedating.[2][3] Patented in 1960, it came into medical use in 1967.[4] Contents 1 Medical uses 2 Side effects 3 Pharmacology 4 Mechanism of action 5 Society and culture 6 References 7 External links Medical...

Avacopan

Avacopan, sold under the brand name Tavneos, is a medication used to treat anti-neutrophil cytoplasmic autoantibody-associated vasculitis.[1][3] Avacopan was approved for medical use in Japan in September 2021,[2] and in the United States in October 2021.[1][3] It is the first orally-administered inhibitor of the complement C5a receptor approved by the U.S. Food and Drug Administration (FDA).[3] C...

Somatropin, rh-GH

Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids.[1][2] It is a type of mitogen which is specific only to the receptors on certain types of cells. GH...

Eprosartan

Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. It is marketed in the United States as Teveten by Abbvie, the spin-off of the pharmaceutical discovery division of Abbott Laboratories; it is marketed as Eprozar by Intas Pharmaceuticals in India, and by Abbott Laboratories elsewhere. The compound came into the Abbott Laboratories cardiovascular pipeline with its acquisition of Kos Pharmaceuticals in 2006, which had licensed it, along with "a ra...

Eprosartan + Hydrochlorothiazide, HCTZ

Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. It is marketed in the United States as Teveten by Abbvie, the spin-off of the pharmaceutical discovery division of Abbott Laboratories; it is marketed as Eprozar by Intas Pharmaceuticals in India, and by Abbott Laboratories elsewhere. The compound came into the Abbott Laboratories cardiovascular pipeline with its acquisition of Kos Pharmaceuticals in 2006, which had licensed it, along with "a ra...

Tisotumab Vedotin-tftv

Tisotumab vedotin, sold under the brand name Tivdak, is an antibody-drug conjugate used to treat cervical cancer.[1] It is a combination of tisotumab, a monoclonal antibody against tissue factor, and monomethyl auristatin E (MMAE), a potent inhibitor of cell division. Tisotumab vedotin was approved for medical use in the United States in September 2021.[1][2] It is administered by infusion into a vein every 3 weeks.[1] Tisotumab ...

Dolutegravir

Dolutegravir (DTG), sold under the brand name Tivicay, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS.[4] It may also be used, as part of post exposure prophylaxis, to prevent HIV infection following potential exposure.[5] It is taken by mouth.[4] Common side effects include trouble sleeping, feeling tired, diarrhea, high blood sugar, and headache.[5] Severe side effects may include allerg...

Dolutegravir Sodium

Dolutegravir (DTG), sold under the brand name Tivicay, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS.[4] It may also be used, as part of post exposure prophylaxis, to prevent HIV infection following potential exposure.[5] It is taken by mouth.[4] Common side effects include trouble sleeping, feeling tired, diarrhea, high blood sugar, and headache.[5] Severe side effects may include allerg...

Indomethacin

Indometacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation. It works by inhibiting the production of prostaglandins, endogenous signaling molecules known to cause these symptoms. It does this by inhibiting cyclooxygenase, an enzyme that catalyzes the production of prostaglandins.[1][2] It was patented in 1961 and approved fo...

Drug Index

Tivozanib, sold under the brand name Fotivda, is a medication used for the treatment of relapsed or refractory advanced renal cell carcinoma (RCC).[2] It is an oral VEGF receptor tyrosine kinase inhibitor.[2] The most common side effects include fatigue, hypertension, diarrhea, decreased appetite, nausea, dysphonia, hypothyroidism, cough, and stomatitis.[2] Tivozanib was approved for medical use in the European Union in August 2017,[3&am...

Fesoterodine Fumarate

Fesoterodine (INN, used as the fumarate under the brand name Toviaz) is an antimuscarinic drug developed by Schwarz Pharma AG to treat overactive bladder syndrome (OAB).[2] It was approved by the European Medicines Agency in April 2007,[3] the US Food and Drug Administration on October 31, 2008 [4] and Health Canada on February 9, 2012.[5] Fesoterodine is a prodrug. It is broken down into its active metabolite, desfesoterodine, ...

Treprostinil Sodium

Treprostinil, sold under the brand names Remodulin for infusion, Orenitram for oral, and Tyvaso for inhalation, is a vasodilator that is used for the treatment of pulmonary arterial hypertension.[1] Treprostinil is a synthetic analog of prostacyclin (PGI2). Treprostinil was approved for use in the United States in May 2002.[2] The drug can be given in various forms: IV, subcutaneous injection, oral inhalation, as well as oral extended-release tablets. The subc...

Flortaucipir F-18

Flortaucipir (18F), sold under the brand name Tauvid, is a radioactive diagnostic agent indicated for use with positron emission tomography (PET) imaging to image the brain.[1][2][3] The most common adverse reactions include headache, injection site pain and increased blood pressure.[1][2] Two proteins – tau and amyloid – are recognized as hallmarks of Alzheimer's disease.[1] In people ...

Tazemetostat Hydrobromide

Tazemetostat, sold under the brand name Tazverik, is a medication used for the treatment of adults and adolescents aged 16 years and older with metastatic (when cancer cells spread to other parts of the body) or locally advanced (when cancer has grown outside the organ it started in, but has not yet spread to distant parts of the body) epithelioid sarcoma not eligible for complete resection (surgically removing all of a tissue, structure, or organ).[1] The most common side eff...

Drug Index

Tolvaptan, sold under the brand name Samsca among others, is an aquaretic drug that functions as a selective, competitive vasopressin receptor 2 (V2) antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH). Tolvaptan was approved by the U.S. Food and Drug Administration (FDA) on May 19, 2009, and is sold by Otsuka Pharmaceutical Co. under the trade name Samsca.[8...

Drug Index

Amino acids are organic compounds that contain amino[a] (.mw-parser-output .template-chem2-su{display:inline-block;font-size:80%;line-height:1;vertical-align:-0.35em}.mw-parser-output .template-chem2-su>span{display:block}.mw-parser-output sub.template-chem2-sub{font-size:80%;vertical-align:-0.35em}.mw-parser-output sup.template-chem2-sup{font-size:80%;vertical-align:0.65em}−NH+3) and carboxylate −CO−2 functional groups, along with a side chain (R group) spec...