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Torsemide

Torasemide, also known as torsemide, is a diuretic medication used to treat fluid overload due to heart failure, kidney disease, and liver disease and high blood pressure.[1] It is a less preferred treatment for high blood pressure.[1] It is taken by mouth or by injection into a vein.[1] Common side effects include headache, increased urination, diarrhea, cough, and dizziness.[1] Other side effects may include hearing loss and lo...

Mequinol + Tretinoin

Mequinol, MeHQ or 4-methoxyphenol, is a phenol used in dermatology[1] and organic chemistry.[2] Contents 1 Uses 1.1 Dermatology 1.2 Organic chemistry 2 Preparation 3 Safety 4 See also 5 References Uses Dermatology Mequinol is a common active ingredient in topical drugs used for skin depigmentation. As a topical drug mequinol is often mixed with tretinoin, a topical retinoid. A common formulation for this drug is an ethanolic solution of 2% mequinol ...

Hydroquinone

Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2. It has two hydroxyl groups bonded to a benzene ring in a para position. It is a white granular solid. Substituted derivatives of this parent compound are also referred to as hydroquinones. The name "hydroquinone" was coined by Friedrich Wöhler in 1843.[7] Contents 1 Production 2 Reactions 2....

Hydroquinone

Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2. It has two hydroxyl groups bonded to a benzene ring in a para position. It is a white granular solid. Substituted derivatives of this parent compound are also referred to as hydroquinones. The name "hydroquinone" was coined by Friedrich Wöhler in 1843.[7] Contents 1 Production 2 Reactions 2....

Diclofenac

Diclofenac, sold under the brand name Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout.[5] It is taken by mouth, rectally in a suppository, used by injection, or applied to the skin.[5][7] Improvements in pain last for as much as eight hours.[5] It is also available in combination with misoprostol in an effort to decrease stomach problems.[8&...

Beta-Carotene

β-Carotene is an organic, strongly coloured red-orange pigment abundant in fungi,[5] plants, and fruits. It is a member of the carotenes, which are terpenoids (isoprenoids), synthesized biochemically from eight isoprene units and thus having 40 carbons. Among the carotenes, β-carotene is distinguished by having beta-rings at both ends of the molecule. β-Carotene is biosynthesized from geranylgeranyl pyrophosphate.[6] In some Mucoralean fungi, ...

Carisoprodol

Carisoprodol, sold under the brand name Soma among others, is a medication used for musculoskeletal pain.[3] Use is only approved for up to three weeks.[3] Effects generally begin within half an hour and last for up to six hours.[3] It is taken orally.[3] Common side effects include headache, dizziness, and sleepiness.[3] Serious side effect may include addiction, allergic reactions, and seizures.[3&#9...

Aspirin, ASA + Carisoprodol

Carisoprodol, sold under the brand name Soma among others, is a medication used for musculoskeletal pain.[3] Use is only approved for up to three weeks.[3] Effects generally begin within half an hour and last for up to six hours.[3] It is taken orally.[3] Common side effects include headache, dizziness, and sleepiness.[3] Serious side effect may include addiction, allergic reactions, and seizures.[3&#9...

Aspirin, ASA + Carisoprodol + Codeine

Carisoprodol, sold under the brand name Soma among others, is a medication used for musculoskeletal pain.[3] Use is only approved for up to three weeks.[3] Effects generally begin within half an hour and last for up to six hours.[3] It is taken orally.[3] Common side effects include headache, dizziness, and sleepiness.[3] Serious side effect may include addiction, allergic reactions, and seizures.[3&#9...

Drug Index

1B9G, 1GZR, 1GZY, 1GZZ, 1H02, 1H59, 1IMX, 1PMX, 1TGR, 1WQJ, 2DSR, 2GF1, 3GF1, 3LRI, 1BQT, 4XSSIdentifiersAliasesIGF1, IGF-I, IGF1A, IGFI, MGF, insulin like growth factor 1, IGFExternal IDsOMIM: 147440 MGI: 96432 HomoloGene: 515 GeneCards: IGF1 Gene location (Human)Chr.Chromosome 12 (human)[1]Band12q23.2Start102,395,874 bp[1]End102,481,744 bp[1]Gene location (Mouse)Chr.Chromosome 10 (mouse)[2]Band10 C1|10 43.7 cMStart87,8...

Drug Index

Somatrem, sold under the brand name Protropin, is an analogue of growth hormone (GH).[1] Somatrem is a recombinant human growth hormone used for the treatment of short stature due to decreased or absent secretion of endogenous growth hormone. Somatrem was first marketed under the brand name Protropin by Genentech in 1985.[2] It differs from endogenous growth hormone by the addition of an extra methionine at the N-terminus[3][circular ref...

Drug Index

Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids.[1][2] It is a type of mitogen which is specific only to the receptors on certain types of cells. GH...

Lanreotide

Lanreotide (INN) is a medication used in the management of acromegaly and symptoms caused by neuroendocrine tumors, most notably carcinoid syndrome. It is a long-acting analogue of somatostatin, like octreotide. Its sequence is H-D-2Nal-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Thr-NH2. Lanreotide (as lanreotide acetate) is manufactured by Ipsen, and marketed under the trade name Somatuline. It is available in several countries, including the United Kingdom, Australia and Canada, and was approved for s...

Pegvisomant

Pegvisomant (trade name Somavert) is a growth hormone receptor antagonist used in the treatment of acromegaly.[1] It is primarily used if the pituitary gland tumor causing the acromegaly cannot be controlled with surgery or radiation, and the use of somatostatin analogues is unsuccessful, but is also effective as a monotherapy.[2] It is delivered as a powder that is mixed with water and injected under the skin.[3] Contents 1 Discovery 2 Struct...

Zaleplon

Zaleplon, sold under the brand names Sonata among others, is a sedative-hypnotic, used to treat insomnia. It is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class.[1] It is manufactured by King Pharmaceuticals and Gedeon Richter Plc. It has been discontinued in Canada but can be manufactured if a prescription is brought to a compounding pharmacy.[2] It was prescribed rarely in the United Kingdom, with zopiclone being the preferred Z-drug by the Nati...

Drug Index

Sorafenib (co-developed and co-marketed by Bayer and Onyx Pharmaceuticals as Nexavar),[1] is a kinase inhibitor drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma. Contents 1 Mechanism of action 2 Medical uses 2.1 Kidney cancer 2.2 Liver cancer 2.3 Thyroid cancer 2.4 Desmoid tumors 3 Adverse effe...

Drug Index

Sotalol, sold under the brand name Betapace among others, is a medication used to treat and prevent abnormal heart rhythms.[1] It is only recommended in those with significant abnormal heart rhythms due to potentially serious side effects.[1] Evidence does not support a decreased risk of death with long term use.[1] It is taken by mouth or injection into a vein.[1] Common side effects include a slow heart rate, chest pain, low bl...

Sofosbuvir

Sofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C.[3] It is taken by mouth.[3][4] Common side effects include fatigue, headache, nausea, and trouble sleeping.[3] Side effects are generally more common in interferon-containing regimens.[5]: 7  Sofosbuvir may reactivate hepatitis B in those who have been previously infected.[7&am...