Sjogrens Hydroxychlor

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Help. I have antiphospholipid antibody syn (aps), sjogrens, small vessell vasculitis, and multiple genetic clotting disorders. I have never felt that 200 mg twice a day of plaquenil has helped me much--been on it 8 years or so. I also take 10 mg prednisone coumadin, and lots other rx. Is it possible I need more plaquenil--like 300 or 400 mg twice a day? I'm dying to know if I could feel better. Nancy ## Have you discussed it with your doctor? From the drug information, it does appear that it can be used in dosages up to 600mgs a day, which would be evenly split at 300mgs twice a day. However, you really do need to discuss it with your doctor, because your full medical information and other medications must all be taken into account, before making any medication changes.

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