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Vigabatrin

Vigabatrin, brand name Sabril, is a medication used to treat epilepsy. It became available as a generic medication in 2019.[1] It works by inhibiting the breakdown of γ-aminobutyric acid (GABA). It is also known as γ-vinyl-GABA, and is a structural analogue of GABA, but does not bind to GABA receptors.[2] Contents 1 Medical uses 1.1 Epilepsy 1.2 Others 2 Adverse effects 2.1 Central nervous system 2.2 Gastrointestinal 2.3 Body as a whole 2.4 Tera...

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Sacituzumab govitecan, sold under the brand name Trodelvy, is a Trop-2-directed antibody and topoisomerase inhibitor drug conjugate used for the treatment of metastatic triple-negative breast cancer and metastatic urothelial cancer.[5][7][8][9] The most common side effects include nausea, neutropenia, diarrhea, fatigue, anemia, vomiting, alopecia (hair loss), constipation, decreased appetite, rash and abdominal pain.[8&am...

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Sacrosidase (trade name Sucraid) is a medication used to replace sucrase in people lacking this enzyme.[1] It is available as an oral solution. Sucraid is approved by the U.S. Food and Drug Administration (FDA) for the therapy of the genetically determined sucrase deficiency that is part of the Congenital Sucrase-Isomaltase Deficiency (CSID). Sucraid assists in the breakdown of sugar/sucrose into simpler forms. Many uses for Sucraid include the relief of gastrointestinal symp...

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Sacubitril/valsartan, sold under the brand name Entresto, is a fixed-dose combination medication for use in heart failure. It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan. It is recommended for use as a replacement for an ACE inhibitor or an angiotensin receptor blocker in people with heart failure with reduced ejection fraction.[7] Potential side effects include angioedema, kidney problems, and low blood pressure.[7&am...

Dextromethorphan + Guaifenesin

Guaifenesin, sold under the brand name Mucinex, among others,[3] is a medication used as an expectorant, intended to help cough out phlegm from the airways.[3] Chemically it is an ether of guaiacol and glycerine. It is unclear if it decreases coughing.[3] Use is not recommended in children less than 6 years old.[4] It is often used in combination with other medications.[3] It is taken by mouth.[3] ...

Drug Index

Safinamide (INN; brand name Xadago) is a drug used as an add-on treatment for Parkinson's disease with "off" episodes; it has multiple modes of action, including the inhibition of monoamine oxidase B.[2][3][4] It was approved in Europe in February 2015,[2] in the United States in March 2017,[3] and in Canada in January 2019.[5] Contents 1 Medical uses 2 Contraindications 3 Adverse effects 4 Overd...

Drospirenone + Ethinyl Estradiol + Levomefolate Calcium

Drospirenone/ethinylestradiol/levomefolic acid (EE/DRSP/LMF), sold under the brand names Beyaz among others, is a combination of ethinylestradiol (EE), an estrogen, drospirenone (DRSP), a progestogen, antimineralocorticoid, and antiandrogen, and levomefolic acid (LMF), a form of vitamin B9, which is used as a birth control pill to prevent pregnancy in women. The formulation contains folate as the calcium salt of levomefolic acid to lower the risk of complications such as fetal neural tube def...

Somatropin, rh-GH

Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of IGF-1 and increases the concentration of glucose and free fatty acids.[1][2] It is a type of mitogen which is specific only to the receptors on certain types of cells. GH...

Salicylic Acid

Salicylic acid is an organic compound with the formula HOC6H4CO2H. A colorless, bitter-tasting solid, it is a precursor to and a metabolite of aspirin (acetylsalicylic acid). It is a plant hormone,[9] and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen.[10] The name is from Latin salix for willow tree. It is an ingredient in some anti-acne products. Salts and esters of salicylic acid are...

Pilocarpine

Pilocarpine is a medication used to reduce pressure inside the eye and treat dry mouth.[1][4] As eye drops it is used to manage angle closure glaucoma until surgery can be performed, ocular hypertension, primary open angle glaucoma, and to bring about constriction of the pupil following its dilation.[1][5][6] However, due to its side effects it is no longer typically used in the long term management.[7&...

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Salbutamol, also known as albuterol and sold under the brand name Ventolin among others,[1] is a medication that opens up the medium and large airways in the lungs.[6] It is a short-acting β2 adrenergic receptor agonist which works by causing relaxation of airway smooth muscle.[6] It is used to treat asthma, including asthma attacks, exercise-induced bronchoconstriction, and chronic obstructive pulmonary disease (COPD).[6] I...

Salsalate

Salsalate is a medication that belongs to the salicylate and nonsteroidal anti-inflammatory drug (NSAID) classes. Salsalate is the generic name of a prescription drug marketed under the brandnames Mono-Gesic, Salflex, Disalcid, and Salsitab. Other generic and brand name formulations may be available.[1] Contents 1 Mechanism of action 2 Medical uses 3 Safety 4 Research 5 History 6 Synthesis 7 References Mechanism of action Relative to other NSAIDs, salsalate has a weak i...

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Salicylamide (o-hydroxybenzamide or amide of salicyl) is a non-prescription drug with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin.[1] Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid. It was also an ingredient in the over-the-counter pain remedy BC Powder but was removed from the formulation in 2009, and Excedrin used the ingredient from 1960 to 1980 in conjunction with...

Drug Index

Salicylic acid is an organic compound with the formula HOC6H4CO2H. A colorless, bitter-tasting solid, it is a precursor to and a metabolite of aspirin (acetylsalicylic acid). It is a plant hormone,[9] and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen.[10] The name is from Latin salix for willow tree. It is an ingredient in some anti-acne products. Salts and esters of salicylic acid are...

Drug Index

Salmeterol is a long-acting β2 adrenergic receptor agonist (LABA) used in the maintenance and prevention of asthma symptoms and maintenance of chronic obstructive pulmonary disease (COPD) symptoms.[2] Symptoms of bronchospasm include shortness of breath, wheezing, coughing and chest tightness. It is also used to prevent breathing difficulties during exercise (exercise-induced bronchoconstriction).[3] It was patented in 1983 and came into medical use in 199...

Mesalamine, 5-ASA

Mesalazine, also known as mesalamine or 5-aminosalicylic acid (5-ASA), is a medication used to treat inflammatory bowel disease, including ulcerative colitis and Crohn's disease.[1] It is generally used for mildly to moderately severe disease.[1] It is taken by mouth or rectally.[1] The formulations which are taken by mouth appear to be similarly effective.[4] Common side effects include headache, nausea, abdominal pain, and feve...

Methyl Salicylate + Menthol

A transdermal analgesic or pain relief patch is a medicated adhesive patch used to relieve minor to severe pain. There are two primary types of analgesic patches: patches containing counterirritants, which are used to treat mild to moderate pain, and patches containing fentanyl, a narcotic used to relieve moderate to severe pain in opioid-tolerant patients. Contents 1 Counterirritant patches 2 Fentanyl patches 3 See also 4 References Counterirritant patches Counterirritant patches cont...

Drug Index

Salsalate is a medication that belongs to the salicylate and nonsteroidal anti-inflammatory drug (NSAID) classes. Salsalate is the generic name of a prescription drug marketed under the brandnames Mono-Gesic, Salflex, Disalcid, and Salsitab. Other generic and brand name formulations may be available.[1] Contents 1 Mechanism of action 2 Medical uses 3 Safety 4 Research 5 History 6 Synthesis 7 References Mechanism of action Relative to other NSAIDs, salsalate has a weak i...

Hydroflumethiazide

Hydroflumethiazide (or Saluron) is a diuretic. Synthesis Hydroflumethiazide synthesis:[1][2][3] Numerous patents, e.g., Lund et al., U.S. Patent 3,254,076 (1966 to Lövens Kemiske Fabrik). See also Bendroflumethiazide References .mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-c...

S-adenosyl-L-methionine, SAM-e

S-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, when marketed as controversial dietary supplement, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver.[1] More than 40 methyl transfers from SAM are known, to various substrates such as nucleic acids, proteins, lipids and secondar...