Ruxolitinib

18 Topics Found
Ruxolitinib Drug Index

Ruxolitinib, sold under the brand names Jakafi and Jakavi, is a medication for the treatment of intermediate or high-risk myelofibrosis,[1] a type of myeloproliferative disorder that affects the bone marrow;[5][6] polycythemia vera (PCV), when there has been an inadequate response to or intolerance of hydroxyurea;[1][7] and steroid-refractory acute graft-versus-host disease.[1] It was developed and...

I hope anyone can share with me if you are currently on Ruxolitinib. I was on Ruxolitinib 40mg each day since sine Dec 2nd 2014. Then I got blast cell of 3%. On the the 6th week my blast cell went up from 6% to 16%. Now entering into the 7th week. Anyone experience a high increase of blast cell & later on a drop to some baseline. Please share.

Filed under Ruxolitinib

Hi, Can someone please help me? i have been on clinical trials of Ruxo for 8 weeks now... i am the 1st of my kind to be put on this drug who has multiple auto-immune diseases and a mutation in my genes. I was put in this drug to try correct alopecia and it has been a great success. Not only has this drug helped me with my hair loss but has also help with my general health. my only issue is my menstrual cycle has stopped and i'm trying to find out if it is connected to these medication or just a coincidence? Many thanks in advance ## You would need much more detailed information. Age? Recent hormone changes/starting and stopping birth control or other medications? Recently lose/gain alot of weight? How regular is your cycle normally? are you pregnant? ## I am 29 and my normal cycle i...

23 REPLIES Filed under Ruxolitinib

Is anybody out there taking the new trial drug Ruxolitinib for Mylofibrosis? ## Yes ## Hello Dave, hope all is going well for you. My husband has recently started taking Ruxolitinub for Mylofibrosis and seems to be responding well, it's still early days (3 weeks to be exact) and feeling much better. How long have you been on this drug and are you responding well? ## Hi Carol. I've been on the drug over 4 months. I started on a sustained release version for a 4 month trial. This trial has stopped and they found the sustained release version did not work as well. I've been on the regular version 15mg twice a day for the past 10 days and I'm feeling pretty good. I've had relief from most of my symptoms and shrunk my spleen from 13.5cm to 7cm. The only complaint I have i...

8 REPLIES Filed under Ruxolitinib

I'm 3 yrs into Post-Essential Thrombocythemia Myelofibrosis, and I'm wondering if anyone out there has taken Ruxolitinib w/what I've got and had any success? ## There are support groups you could check with: Quick Topic...Myelofibrosis Facebook...Myelofibrosis Also several people on tweeter I've found. I have Myelofibrosis, but have not been on Ruxo ## Has anyone tried adopting a low fat high carb raw vegan (primarily fruitarian) lifestyle in addition to juicing leafy greens to see if it has any positive impact on Myelofibrosis? I thought I'd mention this because I've heard of individuals experiencing all different types of miracles over the coarse of a few months to a few years, in relation to getting rid of all types of cancers and other ailments that are other...

3 REPLIES Filed under Ruxolitinib
Jakafi Ruxolitinib

Ruxolitinib, sold under the brand names Jakafi and Jakavi, is a medication for the treatment of intermediate or high-risk myelofibrosis,[1] a type of myeloproliferative disorder that affects the bone marrow;[5][6] polycythemia vera (PCV), when there has been an inadequate response to or intolerance of hydroxyurea;[1][7] and steroid-refractory acute graft-versus-host disease.[1] It was developed and...

Opzelura Ruxolitinib Phosphate

Ruxolitinib, sold under the brand names Jakafi and Jakavi, is a medication for the treatment of intermediate or high-risk myelofibrosis,[1] a type of myeloproliferative disorder that affects the bone marrow;[5][6] polycythemia vera (PCV), when there has been an inadequate response to or intolerance of hydroxyurea;[1][7] and steroid-refractory acute graft-versus-host disease.[1] It was developed and...

JIM HAS NOW BEEN ON RUXOLITINIB FOR 8 WEEKS AND FEELING AND LOOKING MUCH BETTER THAN BEFORE HE STARTED THE MEDICATION. PROBLEM IS HIS ANEMIA IS A PROBLEM, ONLY 7.7 AND TRANSUFISIONS ONCE A WEEK AND HIS PLATLET LEVEL IS WAY UP AT 1200. AFTER THE FIRST 4 WEEKS FELT SO MUCH BETTER, NOW NOT FEELING AS GOOD AS HE WAS. GOING TO THE SPECIALIST ON THURSDAY, MAYBE HIS DOSAGE NEEDS ADJUSTING. ANYONE ELSE HAD THIS PROBLEM? PLEASE SHARE IF YOU HAVE. HE IS TAKING 2OMGS, TWICE A DAY. ## What was his levels before starting? Jim may want to try 15mg twice a day and see if his counts bounce back. ## It would appear that you two have found each other on both active discussions on this medication: This is a very new treatment, so the available information is limited: Carol, how is your husband doing on it...

3 REPLIES Filed under Ruxolitinib

I have stage 3 advanced Myelofibrosis and have been taking Ruxolitinib (Jakafi) for almost 9 weeks. I have had almost 50% reduction in my spleen size and my bloods have returned to close to normal. I am seeing Dr Patrick Tan at Mount Elizabeth Hospital in Singapore and I am paying for the treatment myself as I do not have medical insurance. A bottle of 60 x 5mg pills costs me Singapore$3,450.00 and I get a VAT refund when I leave Singapore if I have not opened the drug before I depart. I am taking 4 x 5mg twice a day so it is quite expensive but the results have been terrific. I can highly recommend yhr hodpital and specialist in Singapore. ## Dear Steve, My mom needs Jakafi too, where I can find it in Singapore at $3,450? Thank you so much, I'm from Chile ## Dear all. My name is St...

4 REPLIES Filed under Ruxolitinib

Hey :) So I have question my dad he has cancer he taking a new medicine called JAKAFI and his Dr he gave to him another medicine called HYDROXYUREA So Do you guys know if any there sife effect to taking both in a same time ? Also he has a problem in spleen and blood Thanks alot please reply me as soon as possible ## Hi Lana, From what I could gather, there are potentially unsafe drug interactions between Jakafi (ruxolitinib) and Hydroxyurea. Quoted below are the precautions you should be aware of: "MONITOR CLOSELY: The concomitant or sequential administration of multiple antineoplastic agents may potentiate the risk and severity of additive toxicities, such as immunosuppression and myelotoxicity. MANAGEMENT: Close clinical and laboratory monitoring for hematologic and nonhematologic...

3 REPLIES Filed under Jakafi

My mom was recently (two weeks ago) put on Jakafi, 10 mg twice daily. Her red blood cells went from 10.5 to 9.9...something like that. I am concerned it's the jakafi as i know that was something we were told to possibly expect. Just wondering if anyone has been on this long term (from the study) or even short term and how they are feeling? ## My dad went on the drug December 20,2011. All levels are dropping, but he feels so much better. Eating great, less night sweats and more energy. Transfusions have increased and the cost per month is outrageous. ## Yes, these types of side effects are listed as being very common when using this medication, which contains Ruxolitinib as the active ingredient. Some other side effects may include dizziness, hematoma, weight gain and herpes zoster. ...

32 REPLIES Filed under Jakafi

I am interested in how soon after starting with ruxolitinib one can feel improvement of symptoms, specifically, fever/chills/night sweats.

Filed under Ruxolitinib
NDC 50881-007 NDC Database

Opzelura 15 mg/g Topical Cream by Incyte Corporation ## Package Codes: 50881-007-04, 50881-007-05 ## Active Ingredients: Ruxolitinib Phosphate

NDC 50881-005 NDC Database

Jakafi 5 mg Oral Tablet by Incyte Corporation ## Markings: INCY;5 ## Shape: Round ## Color: White ## Package Codes: 50881-005-60 ## Active Ingredients: Ruxolitinib

NDC 50881-015 NDC Database

Jakafi 15 mg Oral Tablet by Incyte Corporation ## Markings: INCY;15 ## Shape: Oval ## Color: White ## Package Codes: 50881-015-60 ## Active Ingredients: Ruxolitinib

NDC 50881-025 NDC Database

Jakafi 25 mg Oral Tablet by Incyte Corporation ## Markings: INCY;25 ## Shape: Oval ## Color: White ## Package Codes: 50881-025-60 ## Active Ingredients: Ruxolitinib

NDC 50881-020 NDC Database

Jakafi 20 mg Oral Tablet by Incyte Corporation ## Markings: INCY;20 ## Shape: Capsule ## Color: White ## Package Codes: 50881-020-60 ## Active Ingredients: Ruxolitinib

NDC 50881-010 NDC Database

Jakafi 10 mg Oral Tablet by Incyte Corporation ## Markings: INCY;10 ## Shape: Round ## Color: White ## Package Codes: 50881-010-01, 50881-010-60 ## Active Ingredients: Ruxolitinib

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