Opsumit
3 Topics FoundMacitentan, sold under the brand name Opsumit, is an endothelin receptor antagonist (ERA) developed by Actelion and approved for the treatment of pulmonary arterial hypertension (PAH).[2] The other two ERAs marketed as of 2014 are bosentan and ambrisentan.[2] Macitentan is a dual ERA, meaning that it acts as an antagonist of two endothelin (ET) receptor subtypes, ETA and ETB.[2] However, macitentan has a 50-fold increased selectivity for the ETA...
Macitentan, sold under the brand name Opsumit, is an endothelin receptor antagonist (ERA) developed by Actelion and approved for the treatment of pulmonary arterial hypertension (PAH).[2] The other two ERAs marketed as of 2014 are bosentan and ambrisentan.[2] Macitentan is a dual ERA, meaning that it acts as an antagonist of two endothelin (ET) receptor subtypes, ETA and ETB.[2] However, macitentan has a 50-fold increased selectivity for the ETA...
Opsumit (Macitentan 10 mg) by Actelion Pharmaceuticals Us, Inc. ## Markings: 10 ## Shape: Round ## Color: White ## Package Codes: 66215-501-15, 66215-501-30 ## Active Ingredients: Macitentan