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100+ Topics Found
Omacetaxine Mepesuccinate Drug Index

Omacetaxine mepesuccinate (INN, trade names Synribo ), formerly named as homoharringtonine or HHT, is a pharmaceutical drug substance that is indicated for treatment of chronic myeloid leukemia (CML). HHT is a natural plant alkaloid derived from Cephalotaxus fortunei. HHT and related compound esters of cephalotaxine were described first in 1970, and were the subject of intensive research efforts by Chinese investigators to clarify their role as anticancer and antileukemic agents from the 1970...

Omacor Fish Oil, Omega-3 Fatty Acids

Fish oil is oil derived from the tissues of oily fish. Fish oils contain the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), precursors of certain eicosanoids that are known to reduce inflammation in the body[1][2][medical citation needed] and improve hypertriglyceridemia.[citation needed] There has been a great deal of controversy in recent years about the role of fish oil in cardiovascular diseas...

Omadacycline Drug Index

Omadacycline, sold under the brand name Nuzyra, is a broad spectrum antibiotic medication belonging to the aminomethylcycline subclass[2] of tetracycline antibiotics. In the United States, it was approved in October 2018, for the treatment of community-acquired bacterial pneumonia and acute skin and skin structure infections. Contents 1 In vitro studies 2 Mechanism of action 3 Clinical trials 4 Discovery 5 References 6 External links In vitro studies In vitro studies h...

Omalizumab Drug Index

Omalizumab, sold under the brand name Xolair, is a medication used to treat asthma, nasal polyps, and urticaria.[5][6] Omalizumab is a recombinant DNA-derived humanized IgG1k monoclonal antibody that specifically binds to free human immunoglobulin E (IgE) in the blood and interstitial fluid and to membrane-bound form of IgE (mIgE) on the surface of mIgE-expressing B lymphocytes.[7] Unlike an ordinary anti-IgE antibody, it does not bind to IgE th...

Omapatrilat Drug Index

Omapatrilat (INN,[1] proposed trade name Vanlev) is an experimental antihypertensive agent that was never marketed.[2] It inhibits both neprilysin (neutral endopeptidase, NEP) and angiotensin-converting enzyme (ACE). NEP inhibition results in elevated natriuretic peptide levels, promoting natriuresis, diuresis, vasodilation, and reductions in preload and ventricular remodeling. It was discovered and developed by Bristol-Myers Squibb but failed in clinical tria...

Omaveloxolone Drug Index

Ombitasavir + Paritaprevir + Ritonavir Drug Index

Ombitasvir/paritaprevir/ritonavir, sold under the brand name Technivie among others, is a medication used to treat hepatitis C.[1] It is a fixed-dose combination of ombitasvir, paritaprevir, and ritonavir.[1] Specifically it is used together with dasabuvir or ribavirin for cases caused by hepatitis C virus genotype 1 or 4.[1][2] Cure rates are around 95%.[2] It is taken by mouth.[1] It is generally...

Omegaven Fish Oil Triglycerides

Fish oil, sold under the brand name Omegaven, is a fatty acid emulsion.[2] It is used for total parenteral nutrition (feeding directly into a venous catheter), e.g. in short bowel syndrome.[2] It is rich in omega-3 fatty acids.[2] Fish oil is made up of 2 Omega-3 fatty acids, Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA). It has gained popularity in children in preference to the more commonly used Intralipid after case reports that ...

Omeprazole Drug Index

Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome.[1] It is also used to prevent upper gastrointestinal bleeding in people who are at high risk.[1] Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to other PPIs.[7] It can be taken by mouth or by injection in...

Omeprazole + Sodium Bicarbonate Drug Index

Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome.[1] It is also used to prevent upper gastrointestinal bleeding in people who are at high risk.[1] Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to other PPIs.[7] It can be taken by mouth or by injection in...

Omeprazole + Sodium Bicarbonate + Magnesium Hydroxide Drug Index

Magnesium hydroxide is the inorganic compound with the chemical formula Mg(OH)2. It occurs in nature as the mineral brucite. It is a white solid with low solubility in water (Ksp = 5.61×10−12).[5] Magnesium hydroxide is a common component of antacids, such as milk of magnesia. Contents 1 Preparation 2 Uses 2.1 Precursor to MgO 2.2 Health 2.2.1 Metabolism 2.2.2 History of milk of magnesia 2.3 As food additive 2.4 Other niche uses 2.4.1 Waste water treatment 2....

Omidenepag Drug Index

Omidria Ketorolac + Phenylephrine

Phenylephrine is a medication primarily used as a decongestant, to dilate the pupil, to increase blood pressure, and to relieve hemorrhoids.[2][3] When taken orally as a decongestant, it relieves nasal congestion due to colds and hay fever.[2] It can be taken by mouth, as a nasal spray, given by injection into a vein or muscle, or applied to the skin.[2] Common side effects when taken by mouth or injected include nausea, headach...

Omlonti Omidenepag Isopropyl

Omnaris Ciclesonide

Ciclesonide is a glucocorticoid used to treat asthma and allergic rhinitis. It is marketed under the brand names Alvesco for asthma and Omnaris, Omniair, Zetonna, and Alvesco[1] for hay fever in the US and Canada. Side effects of the medication include headache, nosebleeds, and inflammation of the nose and throat linings.[2] It was patented in 1990 and approved for medical use in 2005.[3] The drug was approved for adults and children 12 and o...

Omni-Ped Stannous Fluoride

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Omnicef Cefdinir

Cefdinir, sold under the brand name Omnicef among others, is an antibiotic used to treat pneumonia, otitis media, strep throat, and cellulitis.[1] It is a less preferred option for pneumonia, otitis media, and strep throat which may be used in those with a severe allergy to penicillin.[1] It is taken by mouth.[1] Common side effects include diarrhea, nausea, and a skin rash.[1] Serious side effects may include Clostridioides diff...

OMNIhist L.A. Chlorpheniramine + Methscopolamine + Phenylephrine

Chlorphenamine (CP, CPM), also known as chlorpheniramine, is an antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis (hay fever).[2] It is taken by mouth.[2] The medication takes effect within 2 hours and lasts for about 4-6.[2] Common side effects include sleepiness, restlessness, and weakness.[2] Other side effects may include dry mouth and wheeziness.[2] It is a first-genera...

Omnipaque Iohexol

Iohexol, sold under the trade name Omnipaque among others, is a contrast agent used for X-ray imaging.[1] This includes when visualizing arteries, veins, ventricles of the brain, the urinary system, and joints, as well as during computed tomography (CT scan).[1] It is given by mouth, injection into a vein, or into a body cavity.[2] Side effects include vomiting, skin flushing, headache, itchiness, kidney problems, and low blood pressure.&#91...

Omnipen Ampicillin

Ampicillin is an antibiotic used to prevent and treat a number of bacterial infections, such as respiratory tract infections, urinary tract infections, meningitis, salmonellosis, and endocarditis.[3] It may also be used to prevent group B streptococcal infection in newborns.[3] It is used by mouth, by injection into a muscle, or intravenously.[3] Common side effects include rash, nausea, and diarrhea.[3] It should not be used in ...

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