Imipramine

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Imipramine Drug Index

Imipramine, sold under the brand name Tofranil, among others, is a tricyclic antidepressant (TCA) mainly used in the treatment of depression. It is also effective in treating anxiety and panic disorder. The drug is also used to treat bedwetting. Imipramine is taken by mouth. Common side effects of imipramine include dry mouth, drowsiness, dizziness, low blood pressure, rapid heart rate, urinary retention, and electrocardiogram changes. Overdose of the medication can result in death. Imipramin...

Hey guys. I've struggled with depression for some time and you know how it goes, mess change here and there, always trying to find that balance. I don't remember why I was taken off of imipramine, and I wasn't on it for long. I think at the time my depression was not terribly severe, and I may have even claimed at that time that I did not have depression. Something was wrong to be sure, but it was mostly that I did not derive joy from anything and was apathetic about life in general and devoid of goals or concern for the future. It was AMAZING. On the tenth day or so, I woke up, looked around the room, and felt that I was seeing the world for the first time. I felt my old feelings were just 'poor reasoning,' and it made sense that regular people carry on with work, f...

1 REPLY Filed under Imipramine

i am on imipramine pamoate 100 mg. and imipramine pamoate 75mg. i have tried other antidepressants. everytime i do try other antidepressante i start having withdrawal effects. the reason i have tried others is because my drug pha. which is cigna charges me over 800 dollars the last three months of each year because i am over 65 and go into what is called the coverage gap. in other words, they are making me pay more for the drug because of the coverage gap. does anyone have a different medicare pharmacy that does not charge so much. they are also classifying imipramine pamoate as a brand rather then genetic. ## Hello, Glenda! How are you? I'm not sure if you'll qualify, but there is an assistance program for Imipramine you can call for more information at 800-259-7765, they do pr...

1 REPLY Filed under Imipramine

I have taken Tofranil PM for over twenty years, with great success. Now that I am retired, I can't afford it and Imipramine Pamote works well, but I can not afford it either. Since it is a generic why is it so high. My insurance will not pay for it either. So I have been ordering it from Canada. They never give me the same meds, it is always a different pill (imipramine HCL). I am afraid I am getting depressed again. Where can I get imipramine pamote at a better price? Is there any help for a old person (71) if Medcare and Humana won't cover this? ## Hello, Skoshilady! How are you? I'm very sorry about the problems that you're having. I didn't find any assistance programs for this medication. What others have you tried? There are many others available that are much c...

2 REPLIES Filed under Imipramine

I have been taking imipramine paomate for 30 yrs. for irritable bowl syndrome along with anxiety, weight loss, depression, diarrhea. This antidepressant has changed my life in that I have been able to go on with a somewhat normal life. It has caused weight gain, dizzness, blurred vision, overeating of sweets , and a feeling of legarthy since I have been on the 175mg dose. When I go think of the way I was when I started on the med. I am thankful it helped me so much but the higher dose of 175 mg is really to strong. I am thinking of going to a Dr. who would be skilled in these things and maybe help me somehow. ## What dosage were you taking previously? Why was it raised to 175mgs? Consulting a specialist would be the best thing to do, in order to get proper treatment, and a proper dosage...

2 REPLIES Filed under Imipramine

Does anybody have something good to say about Imipramine? ## Hi Becky, Surprisingly I haven't really seen too many reviews on Imipramine or how people have been effected by it. What I can tell you though is that most of these types of medications can and usually do affect everyone differently; so going off someone else's experience may not be the best way to gauge how it's going to effect you in the long run. More often than not, people who have a positive reaction to something usually don't take the time to post about it online. So what we typically see on forums is negative reviews for those who it didn't end up working for. Unfortunately the only way to know for certain is to try it for yourself. You can also learn more about this drug on the page for Imipramine D...

2 REPLIES Filed under Imipramine

IS THIS MEDICINE USED FOR PAINFUL INTERCOURSE AND DOES IT CURE IRRITATED URETHA PROBLEMS? ## Hello, Dolores! How are you? I've not heard of it being used for such conditions. This medication is classified by the FDA as a tricyclic antidepressant that's used to treat mental health conditions, though some of them can help with some types of nerve pain, which may be why your doctor prescribed it for you. Its typical side effects are listed as possibly including nausea, dizziness, headache, dry mouth and weight gain. Is there anything else I can help with? ## I was on this medication during my second pregnancy. The doctor took me off 10mg of Valium as was not safe for the baby and put me on Imipramine 10mg throughout the whole pregnancy and thereafter. It was due to me having post-p...

2 REPLIES Filed under Tofranil

My doc has been taking me off 75 mg. dose for about the past two months two weeks. I have finished what he thinks is a reasonable time to wean me off. I have been off the drug since last Thursday..I am having withdrawal at different times of the day...just when I think I am feeling better something else crops up...now I am having indigestion, chills, lethargy...anyone else experience these things when coming off a tranquilizer and how long did it take you to feel better ? ## i've just posted asking about length of time for imipramine withdrawal. I see your post was ages ago. I've done 3 days of sleeping, nausea, headache and generally feeling very unwell. How much longer have got like this?! ## It has taken me two years to reduce my 150mg imipramine to 85mg per day. You should c...

6 REPLIES Filed under Imipramine

I have been taking Imipramine for my panic and anxiety disorder for 23 years. I am now up to 150 milligrams per day. It is still working for my anxiety, but over the last year I'm starting to have weird symptoms. Fast heart beat (went to cardio doctor a few years ago and he says it was normal) heart fluttering, excessive sweating while exercising, facial numbness, body twitching, fatigue, dizziness. I also just turned 50 and am e o weir called big menopausal symptoms. I'm a mess!! It is very hard to find any articles on very long term I promise use. Anyone have any experience with any of these symptoms?? ## Like I think you said it could be very well due to menopause and/or a combination of your body adjusting to the tofranil with less hormones. I seriously doubt that after 23 y...

3 REPLIES Filed under Imipramine

Imipramine - Why am I not able to get this drug anymore? I have been on it since 1989, 100mg at night. I have been off it now for over two weeks, I see no withdrawal symptoms. ## @Shirley, It's amazing to hear that you're not experiencing any sort of withdrawal symptoms after being on an antidepressant for over 25 years and abruptly stopping treatment. That's certainly a good sign and in my opinion may be a reflection of how you've mentally and emotionally overcome the depression Imipramine was treating over the years... But as far as availability is concerned, are doctors or pharmacists telling you that they just can't write or fill prescriptions for it anymore? Or might it just be one or two local pharmacy that are out of stock and simply wont order it any longer d...

1 REPLY Filed under Imipramine

Last dose of Imipramine (25 mg) taken on Monday July 2nd 2012. Under a doctors guidance. Slow, very slow taper. Took 5 months, dropping by 25 mg every three weeks. Began experiencing what I think might be withdrawal symptoms since last dose July 2nd. Symptoms have been: Nose bleeds, Nightmares/Weird Dreams, Profuse sweating at night, Feeling flushed during the day, Headache, Feeling of malaise, Nasal Congestion, Nausea, Insomnia, A bit off, Flu like symptoms and tiredness. I've run these symptoms passed by doctor, but have not heard back from here yet. I was on Imipramine for over 20 years with the highest dosing being 200mg per day. Since Imiprmane is an older drug, I can't seem to find comprehensive information about withdrawal. I'm on day 9 of withdrawal and hoped the sym...

23 REPLIES Filed under Imipramine

I've been on 25 mg of imipramine for 30 years. I've been withdrawing for almost 2 months by 10% per weeek. I had taken the 2% dose for 2 nights. On 3rd night woke up burning all over especially in back of head and gripped by extreme anxiety. Decided to go back up to 5% for a little bit. Still had symptoms; went to full strength again; still same symptoms about 3 to 5 hours after taking drug. These symptoms don't seem like withdrawal symptoms--brain zaps, emotionally unstable--that I'd been experiencing on withdrawal. I would appreciate any information or help. ## Based on my research you may not have been experiencing withdrawal symptoms all along, but more over, general side effects of Imipramine. I'm finding that much of the symptoms you mentioned are listed as sid...

2 REPLIES Filed under Imipramine

I stopped taking imipramine 3 days ago due to unacceptable side effects, which made it not possible to taper the withdrawal (was taking 100mg for 8 weeks prior to cessation). I am having a bad time - nausea, headache, upset stomach, general malaise, vivid dreams and sleepiness. I am struggling to get up and stay awake; I feel so rough... Has anyone had the same experience and can anyone tell me how long I should expect this to go on for please? ## Poor you! I have taken 2 years to reduce from 150mg to 85mg as I have a very understanding doctor. The first week after each reduction is the worst and to help me through this my doc prescribes 12 x 2mg diazepam (no more than that as they are very addictive), I usually take one in the morning then see how the day goes. Couldn't have done i...

5 REPLIES Filed under Imipramine

I've been on 25 mg of imipramine for 30 years. I've been withdrawing for almost 2 months by 10% per weeek. I had taken the 2% dose for 2 nights. On 3rd night woke up burning all over especially in back of head and gripped by extreme anxiety. Decided to go back up to 5% for a little bit. Still had symptoms; went to full strength again; still same symptoms about 3 to 5 hours after taking drug. These symptoms don't seem like withdrawal symptoms--brain zaps, emotionally unstable--that I'd been experiencing on withdrawal. I would appreciate any information or help. ## Hi Barb, If you take a look at Imipramine's list of potential side effects (posted below), I think it'll explain much of the symptoms you're describing: nlm.nih.gov/medlineplus/druginfo/meds/a682389....

2 REPLIES Filed under Imipramine

is this drug used in children for bed wetting ## My son was given this medicine for bed wetting and hyperness and only made the situation worse ## My 13-year-old son used Imipram for bedwetting and the results were wonderful. I'd washed sheets and blankets every single day for years. He quit wetting the bed after about a week. He went off the drug after about 18 months and has never wet the bed again.

2 REPLIES Filed under Imipramine

I just came off of celexa due to side effects (diarrhea). I was on imipramine for depression/panic attacks for 20 plus years. The doctor said celexa had less side effects. Not for me. Anyway I have mennires disease also and need a 2 mg valium....it helps the vertigo some. My problem: Can i take them together at night? ## They can both increase sedation, so you should be cautious taking them, and only do with your doctor's approval. The FDA lists the side effects as possibly including nausea, dizziness, drowsiness, sedation, and shallow breathing. What types of issues did you experience with the Celexa? ## Diarreah that kept on. I have IBS occasionally....but this was different. I have not had daily diarreah or bad pains in over 3 weeks since I came off celexa. I have to take valium ...

2 REPLIES Filed under Imipramine

Has anyone ever heard of this medication being prescribed for withdrawal symptoms from Methadone and if so what do I need to look for as far as side effects. It has been prescribed to my 42 year old husband who is now completely off of Methadone used for chronic pain. ## Well the correct drug name is Imipramine, it is classified as an antidepressant. These are used a lot of times, to help treat withdrawal effects from narcotic drugs, because the narcotics act not only for your pain, but they also have an effect on brain chemicals and stopping them can upset the delicate balance. Here's the monograph link with side effect information: ## I have a friend that is taking Peg Entron w/Remidal. He is having terrible physical and mental side effects side affects. He has Hep -C and Chirrosi...

2 REPLIES Filed under Tofranil

Hi, the online store I normally purchase Imipramine HCL from said that customs prevented it from being sent saying its now considered a narcotic???? I don't understand how this can be. ## If you got a rejection 'love letter' it is possible it is simply a form letter and you were sent the wrong one, Customs has done this before. They should have also sent you an appeal letter saying you can claim the drugs or allow customs to take possession. Assuming you have a valid prescription (you do right?) you can fill out the form and attach a copy of the prescription and send it in hoping for a reversal. It is typically better and faster to simply re-order the medication. You are of course always responsible for any customs import duties that need to be paid. In fact, the customs dut...

1 REPLY Filed under Imipramine

I was on Espazine 2mg for the last 7 years, but now I decided to taper it off. I've also been taking Imipramine 25mg for the last 7 years and sometimes I took 50mg instead of the 25mg dose. Now I've reached a point where I want to continue Imipramine and completely taper off Espazine. Please comment with any suggestions, if any.

Filed under Trifluoperazine

Can I have a glass of wine at night if Im on 25mg of imipramine? ## Imipramine is a tricyclic antidepressant and ingesting alcohol while taking it could result in its being less effective for you, than normal. It may also cause additional impairment of your motor skills. Thus, for many people, one glass of wine may be equal to 2, while they are on this medication. The reactions usually aren't dangerous, but you should make sure you aren't driving or doing anything that could put you or anyone else in danger, if you do choose to imbibe. You should also not be surprised is it seems the medication isn't working, as well. Also due to possible detrimental effects on the liver, you should make sure not drink, a lot. Are there any other questions? ## I took imipramine 50 mg for 4 w...

2 REPLIES Filed under Imipramine

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