Bioavailability

What's the best way to administer Ostospray to ensure maximum absorption? ## Otospray contains the active ingredient Calcitonin and is most commonly used to help protect against bone mineral loss. As to how much is absorbed into the body, I haven't found any information on that. However, with most medications, it is only a small fraction of what is actually in any given dosage. Does anyone else have any information to add?

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prescribed for depression ## would like to know about the bioavailability, solubility, absorption and formulation parameters of melitracen or melitracen-flupentixol hydrochloride. ## i would like the mode of action and side effects of melitracen

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Bacampicillin

Bacampicillin (INN) is a penicillin antibiotic. It is a prodrug of ampicillin with improved oral bioavailability.[1] It is sold under the brand names Spectrobid (Pfizer) and Penglobe (AstraZeneca). Synthesis Semi-synthetic antibiotic related to penicillin. The relatively small chemical difference between ampicillin and benzylpenicillin not only allows for substantial oral activity but also results in a substantial broadening of antimicrobial spectrum so as to allow for use ...

Drug Index

Bacampicillin (INN) is a penicillin antibiotic. It is a prodrug of ampicillin with improved oral bioavailability.[1] It is sold under the brand names Spectrobid (Pfizer) and Penglobe (AstraZeneca). Synthesis Semi-synthetic antibiotic related to penicillin. The relatively small chemical difference between ampicillin and benzylpenicillin not only allows for substantial oral activity but also results in a substantial broadening of antimicrobial spectrum so as to allow for use ...

I understand oxycodone is 1.5x stronger than morphine, but does that take the oral bioavailability into account? I've seen someone say 20mg of oxycodone is equivalent to 30mg of morphine, but is that taking into account that only 30% of the morphine is absorbed by the body whereas with oxycodone it's about 80% So when taking 30mg of morphine you're body is really only getting about 9mg but when taking 20mg of oxycodone you're getting 16mg of it absorbed into your body. I think I am going to be switched from 30mg of Morphine to 10mg of Oxycodone, in terms of bioavailability that means instead of my body getting 9mg of morphine, I'll be getting 8mg of oxycodone instead. Will this be as effective? ## Yes, all of this is taken into account, when the medications are studi...

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when reading about medicines and their TE codes with the FDA, I came across the term moiety of a medicine. Does this mean its bioavailability or does it mean something else? Thank you in advance for your attention and response. Jane ## See definition below: 'In chemistry, a moiety is a specific segment of a molecule. For example, aniline has a phenyl and an amino moiety. Ethidium bromide has both these. '

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As far as the zubsolv go they are 5.7/1.4 mg. That's why they're less potent because of less medicine. They claim the bioavailability is higher but I disagree. Zubsolv are junk. ## I like them. If used correctly they work just fine, but if misused they can give you a headache and are junk. I take them so they do work. ## This is not true. I received 8.6 mg, the highest ones I know of zubsolv. My doctor asked me to try it for one month and they were the strongest form of bupe I've ever taken. I took one and a half the first day because I was skeptical and man I was zooming but insurance wouldn't cover it so it was way too expensive. So I went back to the white 93 or whatever generic they have for me. What's funny is I got the strips for 3 years and all of a sudden the...

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Famciclovir

Famciclovir is a guanosine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster (shingles). It is a prodrug form of penciclovir with improved oral bioavailability. Famciclovir is marketed under the trade name Famvir (Novartis). Famciclovir was patented in 1983 and approved for medical use in 1994.[2][3] In 2007, the United States Food and Drug Administration approved the first generic version of famci...

Drug Index

Famciclovir is a guanosine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster (shingles). It is a prodrug form of penciclovir with improved oral bioavailability. Famciclovir is marketed under the trade name Famvir (Novartis). Famciclovir was patented in 1983 and approved for medical use in 1994.[2][3] In 2007, the United States Food and Drug Administration approved the first generic version of famci...

How long does it take for dificid to leave my system. when can I retest stool specimen to see if c diff is gone! thank you ## Hi Sandy, According to pbm.va.gov, Fidaxomicin (Dificid) is said to have "poor" bioavailability. It is also reported to have an estimated half life of 10-11 hours. With that said, every 11 hours one can simply divide the dose you took in half, then half of that remaining half, etc at each passing time interval in order to estimate how long that particular dose will be working in your body before being excreted. I don't know how long you've been taking Dificid for, how many doses you've taken, or if each dose cumulatively builds up over time, so those are also factors to take into consideration when determining if the medication is still presen...

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to cut in half the amox tr-k clv 875-125 still efective? ## I think the answer is simple; if you cut the pill in half, it will be half as effective as the "normal" dose would be. Any drugs effectiveness is also attributed to its bioavailability and the consumers ability to assimilate and utilize its contents. This depends on weight, height, current health, whether or not you are currently dealing with other illnesses, etc...Your doctor who prescribed this dosage to you should understand this and has given you that dosage based on those factors among other personal factors. ## as long as a pill has that ingraved (excuse me i forget the technical term) line in the middle then yes the pill is split evenly in half if cut at that line , which the amox trk clv pills do have so yes. fo...

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round, peach color, 634 on one side , FD on the other ## Hello, Mcgiver! How are you? This tablet contains 5mgs of Butorphanol, which is an opioid analgesic. This tablet is most commonly prescribed for cats and dogs, because the tablet form has a very low level of bioavailability in humans. Side effects may include nausea, dizziness, drowsiness, dry mouth and constipation. It also carries the risk of being habit forming. Is there anything else I can help with?

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Benfo Forte is used for diabetic, alcoholic and peripheral neuropathy. This is a vitamin blend used to protect your peripheral system from neural pains, which is a common as we age. Moreover Benfotiamine being a both fat and water soluble form of Thiamine ( Vitamin B1) so it's bioavailability is much more than the usual Thiamine. ## i would like to know the strength of Thiamine in Benfo Forte and Bencimine Forte ## is benfo forte & benfomet same cap. ?

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Has anyone had the Sublocade injection? I'm seriously thinking about switching from the films to the monthly injection. ## I haven't tried it, but do think it would be interesting to read how the shot compares to the films or sublingual tablets with regards to efficacy, bioavailability, duration of effects and so forth. According to the manufacturer, "In a 24-week clinical study, people who received Sublocade plus counseling were more likely to have weeks without opioid use compared with people who received a placebo shot (an inj. with no medication) plus counseling." Source: sublocade.com Also, there are some people who take Subutex (buprenorphine) for pain management instead of opioid cravings even though it's not specifically indicated for such use. I'd like t...

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What is the difference in taking the Saboxin strips as opposed to taking the pill? ## The reasons for choosing film over tablets can be different for each person, however from what I could gather, several patients said the film dissolved much faster and felt that they got better absorption or bioavailability with the film for that reason. If you have to take the medication several times per day (including while at work), then the disposable film packaging may not be as discrete as you'd like. You might have to be creative with the package disposal, so no one at work will see a discarded pouch and discover you're on Suboxone, if that is even a concern for you. Also some patients note that the films tasted better than the tablets. On the downside, "some" patients report th...

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When you have the option of taking a drug sublingually, does taking it in that fashion in any way dissolve away or lessen the impact of the inactive ingredients, rendering the intended drug effects more equal between brands? ## I'd also like to add whether the bioavailability of the drug between two brands becomes more identical when the drug is administered sublingually as opposed to swallowed. ## Hello Schleprock, All routes of administration of the same dosage of a drug regardless of brand are required by the FDA to meet a standardized number of the active ingredient entering your blood stream. For example all generic versions of 100mg tylenol (acetaminophen), regardless of administration route, are required by the FDA to have +/- 20% of amount of acetaminophen in your blood stre...

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an antibiotic that treats bacterial overgrowth in intestine. Dose is 600 mg/day for 10 days. ## Rifaximin is a semisynthetic antibiotic that's most commonly used to treat traveler's diarrhea and hepatic encephalopathy. Learn more Rifaximin details here. It's main problem is that it has poor oral bioavailability, so little of it is absorbed if it's swallowed. Are there any questions or comments?

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is gernaric and brand name the same ? if not whats different? ## is genaric as good as brand? ## Yes, generics should generally work as effectively as the brand name of the medication [1]. There are, however, exceptions. Because inactive ingredients may differ, not to mention different standards across multiple manufacturers, a generic's bioavailability of the active ingredient(s) may differ by as much as 20% [2]. So while generic drugs are not necessarily worse than their brand name equivalent, some may experience slightly different effects across multiple versions of the same medication. Ultimately it is a good idea to monitor how you feel, and if you do experience anything unusual, contact your doctor right away. Do you have any other questions or information to add? Please post ...

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what kind of medication is Ancept ## Hello, Are you referring to Aricept (Donepezil)? If so, it is classified as a centrally acting reversible acetylcholinesterase inhibitor which is most commonly used for the palliative treatment of mild to moderate Alzheimer's Disease. Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a half-life of about 70 hours, it can be taken once a day. You can learn more about this drug on the page for Aricept Details I hope this info helps!

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Tocainide

Tocainide (Tonocard) is a class Ib antiarrhythmic agent. It is no longer sold in the United States. Contents 1 Pharmacokinetics 2 Synthesis 3 References 4 Further reading 5 External links Pharmacokinetics Tocainide is a lidocaine analog, that does not have significant 1st pass metabolism. It is found in two enantiomers. The R isomer is 4x as potent as the S. Oral bioavailability is 0.9-1.0. In the blood tocainide is 10-20% protein bound. The Volume of distribution is 2.5-3.5 L/kg. ...