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Drug Index

A multivitamin is a preparation intended to serve as a dietary supplement with vitamins, dietary minerals, and other nutritional elements. Such preparations are available in the form of tablets, capsules, pastilles, powders, liquids, or injectable formulations. Other than injectable formulations, which are only available and administered under medical supervision, multivitamins are recognized by the Codex Alimentarius Commission (the United Nations' authority on food standards) as a category ...

Insulin Glargine

Insulin glargine [GLAR geen], sold under the brand name Lantus among others, is a long-acting insulin, used in the management of type I and type II diabetes.[6] It is typically the recommended long acting insulin in the United Kingdom.[7][contradictory] It is used once a day as an injection just under the skin.[6] Effects generally begin an hour after use.[6] Common side effects include low blood sugar, problems a...

Drug Index

Basiliximab (trade name Simulect) is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants. Contents 1 Uses 2 Mechanism of action 3 Chemistry 4 History 5 See also 6 References and notes Uses Basiliximab is an immunosuppressant agent used to prevent immediate transplant rejection in people who are receiving kidney transplants, in combination with o...

Drug Index

Besifloxacin (INN/USAN) is a fourth-generation fluoroquinolone antibiotic. The marketed compound is besifloxacin hydrochloride. It was developed by SSP Co. Ltd., Japan, and designated SS734. SSP licensed U.S. and European rights to SS734 for ophthalmic use to InSite Vision Incorporated (OTC Pink: INSV) in 2000. InSite Vision developed an eye drop formulation (ISV-403) and conducted preliminary clinical trials before selling the product and all rights to Bausch & Lomb in 2003.[1&am...

Besifloxacin

Besifloxacin (INN/USAN) is a fourth-generation fluoroquinolone antibiotic. The marketed compound is besifloxacin hydrochloride. It was developed by SSP Co. Ltd., Japan, and designated SS734. SSP licensed U.S. and European rights to SS734 for ophthalmic use to InSite Vision Incorporated (OTC Pink: INSV) in 2000. InSite Vision developed an eye drop formulation (ISV-403) and conducted preliminary clinical trials before selling the product and all rights to Bausch & Lomb in 2003.[1&am...

Inotuzumab Ozogamicin

Inotuzumab ozogamicin, sold under the brand name Besponsa, is an antibody-drug conjugate medication used to treat relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).[1][2] The medication consists of a humanized monoclonal antibody against CD22 (inotuzumab), linked to a cytotoxic agent from the class of calicheamicins called ozogamicin.[3] This drug was discovered by scientists collaborating at Celltech and Wyeth, and it w...

Ropeginterferon alfa-2b-njft

Ropeginterferon alfa-2b, sold under the brand name Besremi, is a medication used to treat polycythemia vera.[1][2][3][4] It is an interferon.[1][3] It is given by injection.[1][3] The most common side effects include low levels of white blood cells and platelets (blood components that help the blood to clot), muscle and joint pain, tiredness, flu-like symptoms and in...

Drug Index

Bisacodyl (INN) is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of episodic and chronic constipation and for the management of neurogenic bowel dysfunction, as well as part of bowel preparation before medical examinations, such as for a colonoscopy.[1][2] Bisacodyl is a derivative of triphenylmethane. It was first used as a laxative in 1953 becau...

Drug Index

Polyethylene glycol (PEG; /pliθlin lakl, -θl-, -kl/) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG is commonly expressed as H−(O−CH2−CH2)n−OH.[3] Contents 1 Uses 1.1 Medical uses 1.2 Chemical uses 1.3 Biological uses 1.4 Commercial uses 1.5 Industr...

Drug Index

Metronidazole, marketed under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication.[4] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis.[4] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.[4] It is an option for a first episode of mild-to-moderate Clostridium difficile colitis if vancomycin or fidaxomicin is una...

Bismuth Subsalicylate

Bismuth subsalicylate, sold generically as pink bismuth and under the brand names Pepto-Bismol and BisBacter, is an antacid elixir medication used to treat temporary discomforts of the stomach and gastrointestinal tract, such as nausea, heartburn, indigestion, upset stomach, and diarrhea. Bismuth subsalicylate has the empirical chemical formula of C7H5BiO4,[1] and it is a colloidal substance obtained by hydrolysis of bismuth salicylate (Bi(C6H4(OH)CO2)3). Contents 1 Medical ...

Drug Index

Bismuth subsalicylate, sold generically as pink bismuth and under the brand names Pepto-Bismol and BisBacter, is an antacid elixir medication used to treat temporary discomforts of the stomach and gastrointestinal tract, such as nausea, heartburn, indigestion, upset stomach, and diarrhea. Bismuth subsalicylate has the empirical chemical formula of C7H5BiO4,[1] and it is a colloidal substance obtained by hydrolysis of bismuth salicylate (Bi(C6H4(OH)CO2)3). Contents 1 Medical ...

Drug Index

Bismuth subsalicylate, sold generically as pink bismuth and under the brand names Pepto-Bismol and BisBacter, is an antacid elixir medication used to treat temporary discomforts of the stomach and gastrointestinal tract, such as nausea, heartburn, indigestion, upset stomach, and diarrhea. Bismuth subsalicylate has the empirical chemical formula of C7H5BiO4,[1] and it is a colloidal substance obtained by hydrolysis of bismuth salicylate (Bi(C6H4(OH)CO2)3). Contents 1 Medical ...

Drug Index

Bisoprolol, marketed under the tradename Concor among others, is a beta blocker medication most commonly used for heart diseases.[4] This specifically includes high blood pressure, chest pain from not enough blood flow to the heart, and heart failure.[4][5] It is taken by mouth.[4] Common side effects include headache, feeling tired, diarrhea, and swelling in the legs.[4] More severe side effects include worsening...

Drug Index

Bisoprolol, marketed under the tradename Concor among others, is a beta blocker medication most commonly used for heart diseases.[4] This specifically includes high blood pressure, chest pain from not enough blood flow to the heart, and heart failure.[4][5] It is taken by mouth.[4] Common side effects include headache, feeling tired, diarrhea, and swelling in the legs.[4] More severe side effects include worsening...

Drug Index

Bisoprolol, marketed under the tradename Concor among others, is a beta blocker medication most commonly used for heart diseases.[4] This specifically includes high blood pressure, chest pain from not enough blood flow to the heart, and heart failure.[4][5] It is taken by mouth.[4] Common side effects include headache, feeling tired, diarrhea, and swelling in the legs.[4] More severe side effects include worsening...

Drug Index

Bosentan, sold under the brand name Tracleer and Safebo among others, is a dual endothelin receptor antagonist medication used in the treatment of pulmonary artery hypertension (PAH).[2][3] Bosentan is available as film-coated tablets (62.5mg or 125mg) or as dispersable tablets for oral suspension (32mg).[2] Contents 1 Medical uses 2 Adverse effects 3 Mechanism of action 4 Pharmacokinetics 5 History 6 Society and culture 6.1 Economics 7 See...

Bosutinib

Bosutinib (rINN/USAN; codenamed SKI-606, marketed under the trade name Bosulif) is a small molecule BCR-ABL and src tyrosine kinase inhibitor used for the treatment of chronic myelogenous leukemia. Originally synthesized by Wyeth, it is being developed by Pfizer. Contents 1 Mechanism 2 Medical uses 3 Contraindications 4 Interactions 5 Notes 6 See also 7 References 8 External links Mechanism It is an ATP-competitive Bcr-Abl tyrosine-kinase inhibitor with an additional inhibitory effect...

Drug Index

Bosutinib (rINN/USAN; codenamed SKI-606, marketed under the trade name Bosulif) is a small molecule BCR-ABL and src tyrosine kinase inhibitor used for the treatment of chronic myelogenous leukemia. Originally synthesized by Wyeth, it is being developed by Pfizer. Contents 1 Mechanism 2 Medical uses 3 Contraindications 4 Interactions 5 Notes 6 See also 7 References 8 External links Mechanism It is an ATP-competitive Bcr-Abl tyrosine-kinase inhibitor with an additional inhibitory effect...

Buspirone

Buspirone, sold under the brand name Buspar, among others, is a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder.[9][10] Benefits support its short-term use.[11] It is taken by mouth, and it may take up to four weeks to have an effect.[9][10] Common side effects of buspirone include nausea, headaches, dizziness, and difficulty concentrating.[9]&#91...