Arthrotec

Diclofenac + Misoprostol

Diclofenac/misoprostol, sold under the brand name Arthrotec, is a fixed-dose combination medication that contains: Diclofenac sodium: Nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties Misoprostol: Gastrointestinal (GI) mucosal protective prostaglandin E1 analog. In the United Kingdom it is marketed by Pharmacia and it is indicated for prophylaxis against NSAID-induced gastroduodenal ulceration in people requiring diclofenac for rheumatoid arthritis or osteoarthritis.&...

can i take arthrotec if i am alergic to sulfas ## Hi ron, I have found no reports stating that Arthrotec contains sulfa. This medication is a combination of an ulcer protective agent called misoprostol and the NSAID diclofenac; neither of which contain sulfa nor carry any contraindications to use in patients allergic to sulfa(s). Did you have any other questions or concerns regarding this medication? Please post back if you do.

1 REPLY

bursitis ## I have terrible pain in my knees so I consulted an orthopaedic and he has prescribed rotec t5 after an x'ray. I just want to know the side effects of this medicine and whether I should go for other tests? ## Arthrotec contains Diclofenac, which is a nonsteroidal anti-inflammatory, and Misoprostol, which is used to help protect the stomach from the damage that the Dicolfenac could potentially cause. Other side effects may include nausea, dizziness, headache, and increased risk of bleeding. It is often prescribed to help with such conditions, because it can reduce the inflammation that contributes to the pain these conditions can cause. Parwez, what diagnosis did he provide after viewing the x-rays and doing an exam? It is always your option to see another doctor for anoth...

2 REPLIES

Will taking diclofenac/misoprostol separately (generics for the drugs in Arthrotec) be as effective as taking them combined as one pill. It will be much less expensive to take 2 generics. ## It's possible, but hard to say, have you tried asking your doctor or pharmacist about this? The Diclofenac is a nonsteroidal anti-inflammatory and the Misoprostol is there, really, just to help protect your stomach from the irritation and damage it may cause. Some of the most common side effects of using this include: nausea, drowsiness, headaches and diarrhea. You can read more about them here: Is there anything else I can help you with? ## Absolutely not! My insurance company would not pay for the arthrotec75 because the two items could be obtain generically. The seperate pills, diclofenac and...

3 REPLIES

WENT TO DOCTOR WHO SAID I HAD INFLANATION OF THE BONE AND LIGAMENTS OF MY SHOULDER FROM LIFTING WEIGHTS ARTHROTECK AFTER EVEN DAY ONE <TOOK SWEELING DOWN DRAMATICALLY AND REDUCED PAIN SENSITIVITY VERY GOOD SO FAR A LITTLE UNSET STOMACH BUT NOT TOO BAD.

I seem to be doing fine with the xarelto, but my arthritis is killing me without my prescription pain reliever, Arthrotec. Does anyone take arthrotec with Xarelto? If not, what pain killer can I take? I tried an opiod and it made me foggy and unsteady on my feet. I am sensitive to meds and arthrotec really helped me, which is why I miss it so much. ## Hi Judy, According to umm.edu's drug interaction checker, there ARE interactions listed between Xarelto (Rivaroxaban) and Arthrotec (Diclofenac sodium). The interaction goes on to state that taking these two drugs together may increase your risk of bleeding. Furthermore, they recommend contacting your doctor as soon as possible if you experience any of the following side effects, such as long lasting nose bleeds, dark or bloody vomit, ...

2 REPLIES

Can I take arthrotec and rivocacet at the same time? ## Sorry the name of it is spelled rivacocet ## Arthrotec contains the active ingredients Diclofenac and Misoprostol, it couples a nonsteroidal anti-inflammatory with a medication to prevent it from causing gastrointestinal damage. Learn more Diclofenac details here. Learn more Misoprostol details here. Rivacocet contains the active ingredients Oxycodone and Acetaminophen, so it's a narcotic analgesic. Learn more Rivacocet details here. And yes, they are sometimes used together to help someone get better pain control, since they aren't in the same drug classes. However, if your doctor has instructed you not to combine them, then there may be reasons for that and you should follow their instructions. Additionally, you should kn...

2 REPLIES

has anyone had any bad side effects with this drug? ## Side effects are possible with any medication, some are worse than others and they will affect everyone differently. Arthrotec contains Diclofenac and Misoprostol, this combines a nonsteroidal anti-inflammatory with another agent to help prevent stomach irritation and ulcers. Possible side effects include: nausea, drowsiness, blood thinning and headache. Is there anything else I can help you with?

1 REPLY

Until Dec 2016 I have been taking Arthrotec for years and never had a problem. Walmart will not take my plan D Envision RX Plus and so I switched to Walgreens which will. I am allergic to sulfa, sulfite, etc. and when I got Walgreens Arthrotec I got sick and had a blood clot. I ended up on Coumadin for probably the rest of my life and the doctor does not want me to take Arthrotec. Does Walgreens get their Arthrotec from Canada or some place that has a filler with sulfa? Arthrotec has worked for the pain of osteoarthritis and I do not want to have to go in the hospital again or give up the Arthrotec. They have told me to use Tylenol but it is useless. ## Hello Barb, I realize it's been one month since you asked this question and I don't have a direct answer for you. What I will s...

4 REPLIES

There are generics available for the drugs that are in arthrotec and I am wondering if it will be as effective if I take them separately. It would be a lot less expensive. ## You can find Arthrotec 50 for about $ .50 per pill versus approximately 8 times that price from an americam drug company. These are made by Pharmicia Limited (a Pfizer subsidery) ## Yes, taking them separately will still work the same as taking them combined in one medication. It is often done, if it is cheaper for someone than buying the combined, or name brand medication. The FDA lists its typical side effects as possibly including nausea, dizziness, headache, increased risk of bleeding and stomach irritation. Arthrotec is listed as containing Diclofenac and Misoprostol. Is there anything else I can help with?

2 REPLIES

my grandfather in in a nursing home, he is on all these meds, he is not himself anymore, we need to know what these drugs are all for. ## I don't know, but you can find out here: Just put the drug names in the search box; it will give you all the info you get from the pharmacy inserts.

1 REPLY

ARTHRITIS MEDICINE ## Arthrotec contains the active ingredients Diclofenac and Misoprostol. The Diclofenac is a nonsteroidal anti-inflammatory that's used to help treat pain and swelling, while the Misoprostol is used to help prevent the stomach damage that the NSAID can cause as a side effect. Learn more Diclofenac details here and there are more Misoprostol details here. Side effects may include nausea, dizziness and headache. Are there any questions or comments?

1 REPLY

Drug Index

Diclofenac/misoprostol, sold under the brand name Arthrotec, is a fixed-dose combination medication that contains: Diclofenac sodium: Nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties Misoprostol: Gastrointestinal (GI) mucosal protective prostaglandin E1 analog. In the United Kingdom it is marketed by Pharmacia and it is indicated for prophylaxis against NSAID-induced gastroduodenal ulceration in people requiring diclofenac for rheumatoid arthritis or osteoarthritis.&...

Now that I am taking pradaxa, I can no longer take arthrotec for arthritis. Is there any other arthritis medication I can take? ## Hello, Denis! How are you? You should be able to take medications that don't cause blood thinning, which the Diclofenac in the Arthrotec does. (Diclofenac NDC code for more information 0054-4223.) The FDA lists the typical side effects of Pradaxa as possibly including nausea, headache, increased risk of bleeding, and easy bruising. (Pradaxa 0597-0149). What other medications have you tried? ## I have taken no other medication for arthritis except hydrocodone, 1 a day. This does not do much except for a short time and does contain acetaminophen which can cause liver problems. Since the arthritis is long term (30+ yrs so far, I am 62) I am looking for opti...

2 REPLIES

I seem to be doing fine with the xarelto, but my arthritis is killing me without my prescription pain reliever, Arthrotec. Does anyone take arthrotec with Xarelto? If not, what pain killer can I take? I tried an opiod and it made me foggy and unsteady on my feet. I am sensitive to meds and arthrotec really helped me, which is why I miss it so much. ## Hello, Judy! How are you doing? I'm very sorry that you're in pain. You can't take NSAIDs, such as Arthrotec with Xarelto, since they cause blood thinning. Other side effects, as listed by the FDA, may include nausea, dizziness and headache. Which opiate did you try? Those can be normal side effects of them. They FDA lists them as being narcotic analgesics, so they have the potential to be habit forming and may cause side effec...

1 REPLY

just need to know what it is and it s uses ## Hi Jim, The imprint on this pill is actually 1421 as opposed to 421. "Searle 1421" is identified as Arthrotec (diclofenac sodium 75 mg + misoprostol 200 mcg). This medication is prescribed for treatment of arthritis symptoms while at the same time providing protection from the development of stomach and intestinal ulcers due to the arthritis medication. You can read more about this drug by following the link below: Did you have any other questions or comments regarding Arthrotec?

1 REPLY

I just found Rumoquin NF at Mexipharmacy. They don't seem to take credit cards, but offer other ways to buy. I've been taking Arthrotec 75 for about 14 years for arthritis all over my body. My pain seems to respond favorably to diclofenac and Arthrotec 75 contains misprostol as well, a stomach protectant. However, I ran out when last in Mexico and was sold Rumoquin NF at a farmacia. The diclofenac worked its wonders, but the additional ingredients, dexamethasone and methocarbamol, seem to potentiate the relief. Rumoquin NF is also orders of magnitude cheaper and I generally need take only one per day. Win/win. ## i would like to order some of the rumoquin how much is it? im from sacramento, ca ## Stacey, try mexipharmacy. Rumoquin NF is not easy to find, but seems to be sold pri...

6 REPLIES

white round says searle 1421 on one side and 75 with 4 A's on other ## This pill is called OrthoPro it is used for arthritis and is an anti-inflammatory. ## This medication is actually called Arthrotec, it contains 75mgs of Diclofenac and 200mcgs of Misoprostol, so it combines a nonsteroidal anti-inflammatory with the Misoprostol to help protect the stomach from the damage that they can cause, such as ulcerations. It treats pain and swelling and it may still cause other side effects, that can include nausea, dizziness, headache and drowsiness. Learn more Diclofenac details here and you can learn more Misoprostol details here. Are there any questions or comments? ## Used searles 1421 not sure if pregnant or not because i didnt see my periods. I took 2 tablets through the mouth

3 REPLIES

I have Osteoarthritis, possibly Fibromyalgia, and two knees that are bone-on-bone and need replacement. Even though I take Tramadol 300 ER daily and Arthrotec, 2 Tylenol, and 2 Aleve three times a day, I am still in pain. Forgetting to take meds or being out of meds for a day causes unbelievable aches everywhere except my fingers, elbows and toes. I cannot work and cannot sleep. I also get very emotional and angry and my BP goes up. I will soon be having my first knee replaced. The doctor said I will need to be off all the pain meds except for Tylenol. I do not believe I can do this. A couple times the doctor has given me steroids when I was having a flare up and it completely eliminated the swelling and pain. What medications could I safely take in the 2 weeks prior to knee replacement...

1 REPLY

White round pill marked searle 1411 on one side and on the reverse four A with 50 in the center ## white pill the front SEARLE 1411 on reverse four A's with 50 in the middle ## This is an Arthrotec tablet, it contains 50mgs of Diclofenac and 200mgs of Misoprostol, it is most commonly used to treat the pain and inflammation associated with arthritic conditions. Learn more Arthrotec details here. Side effects may include nausea, dizziness, headache and drowsiness. Are there any comments or questions?

2 REPLIES