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just want to know if Daflon 500 is not given to patient with chronic liver disease ... ## Since this medication is not approved for use in the U.S. and Canada, I am afraid that I don't have any information on that. Have you asked your doctor? Daflon is actually a purified flavanoid used as a venotonic. ## Here's research info from France, where Dalfon has been used for years. Angiology. 1994 Jun; 45 (6 Pt 2): 579-84. Safety and security of Daflon 500 mg in venous insufficiency and in hemorrhoidal disease. Daflon 500 mg is a new flavonoid vasoprotector venotonic agent whose active principle is micronized and contains 90% diosmin and 10% flavonoids expressed as hesperidin. In animal studies, the safety of Daflon 500 mg is shown by an LD50 (lethal dose 50) of more than 3 g/kg, ie, ...

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