Active Ingredient(s): Rivaroxaban
FDA Approved: * July 1, 2011
Category: Blood Thinner (Anticoagulant)

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Xarelto Overview

Rivaroxaban, sold under the brand name Xarelto, among others, is an anticoagulant medication (blood thinner), which is taken by mouth. It is commonly used to prevent blood clots. It was initially developed by Bayer. In the United States, it is marketed by Janssen Pharmaceutica. It is the first available active direct factor Xa inhibitor which is taken by mouth. The maximum inhibition of factor Xa occurs four hours after a dose. The effects last approximately 8–12 hours, but factor Xa ac...

Read more Xarelto Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Rivaroxaban

Recent Xarelto Forums: RSS Feed

Xarelto and alcohol
1 Reply RSS
I have been taking xarelto regularly for about 3 months. I am noticing when I have a drink I get very nauseous and the next day I have diarrhea, nausea and vomiting. I am wondering if anyone else has experienced this? ## Drinking alcohol with most medications will worsen the side effects, according to FDA reports. You may also experience dizziness, and headaches. It is usually best not to drink while taking any prescription medication. They usually do not work well together. Alcohol can also cause additional blood thinning. How are you doing, now?
Updated 1 day ago.
Spinal anesthetic on xarelto patient
1 Reply RSS
I have just read a notice about safety concerns if you are on xarelto and are going to have spinal anesthesia if you have had previous spinal injections. I had between seven and ten cortisone shots in my lower back between 2011and 2014, followed by radial ablation on both sides in 2014. I will be having knee surgery in a month and my doctor mentioned that he uses a spinal anesthetic. I won't be seeing him till a couple of days before the surgery and wonder if that is a little late to discuss it with him. Do you have information on what percentage of patients have problems? ## I've been asked to give more information about my problem. I have looked at other blogs and it seems that Xeralto has been given to patients for other reasons than AF. These patients have been taken off of ...
Updated 3 days ago.
xarelto fluid retention
147 Replies RSS
I had to take Xarelto due to two sinus venous thrombosis in my head. 8 weeks of heparin injections showed no side effects. But with the first day of taking Xarelto my body reacted by retaining water. Within the first three weeks I gained 24.46 lb hill exercising 5 times a week and eating as I always did. After retaining more and more water I stopped taking it after three months. I started with a weight of 120 lb at a height of 5''8 and now I weigh 157 lb. I have to ad that I started taking it in the middle of March and stopped taking it at the end of June. I was not able to loose any water/weight. I eat less than I always did before even while I exercise. All doctors couldn't find the one thing that changed through Xarelto. Has anybody ever experienced something like this wh...
Updated 4 days ago.
water retention
6 Replies RSS
I am 37 years old and have gained an excessive amount of weight in the last couple years and it's getting worse every month. It's mostly around my belly but I've noticed in my legs that I have a lot of water. My fingers also seem to tingle a lot too. ## Hello, Daylyn! How are you doing? I'm very sorry about the problem that you're having. And I urge you to see your doctor, as soon as possible. What many people aren't aware of is that such extreme fluid retention can put you at risk of congestive heart failure and it may cause high blood pressure. Both of which require treatment for your own safety. Are you on any medications that might be causing it? ## No, No medications. And also No insurance. Going to the Dr can be very expensive. Probably the biggest reason I...
Updated 5 days ago.
Xarelto and exercise and fatigue
6 Replies RSS
I have been on Xarelto for 4 months. I am trying to exercise but still feel so fatigued. I was very active before my DVT/PE (1/2 marathons, cycling, lifting) and just having a hard time feeling normal when exercising. Feel very out of breathe when only running 3-5 miles. Can't seem to run more than 5 miles now! Anyone else experience this? Also I have gained about 10 lbs and can't seem to lose it! Feeling very frustrated! ## Hello, CJ! How are you? Yes, those are known side effects of Xarelto, as listed by the FDA. You may also experience headache, increased risk of bleeding, easy bruising and joint.muscle aches. Can anyone that's been on it chime in with their experience? Some people have had to stop taking it, due to the side effects. ## CJ, my profile is similar to yours....
Updated 8 days ago.
Extreme fatigue on Xarelto
30 Replies RSS
Hello, Hope someone can help. I've been hitting a wall of fatigue everyday about 1pm to the point where I need to take a 2 hour nap when my daughter is napping and its painful to wake up even after that. I take Xarelto everyday with dinner to treat a DVT. I've been on it 4 months. Is this a known side effect? I tested my theory when I started to realize this began after taking Xarelto and skipped a dose one evening. The following day I didn't need a nap and didnt have that same debilitating exhaustion. I'm only 34 this is no time to be this tired after a full nights sleep! It feels like a crash, an unnatural exhaustion. Thanks! AS ## Hi! Sorry about the problem that you're having. Unfortunately, I haven't been able to find a lot of side effect information on this...
Updated 8 days ago.
xarelto cause leg pain
3 Replies RSS
Hi, I'm Redd, I've been on Xarelto for 6 weeks now due to 3 DVTs and 2 PEs and I'm just now beginning to experience the leg pains, how long do they normally last? ## Hello, Redd! How are you? Actually, sometimes they don't. Many people experience such issues for the duration of treatment and have had to stop the medication early, or switch to something else. The same applies to the other side effects listed by the FDA, which may include nausea, headache, increased risk of bleeding and easy bruising. Have you consulted your doctor? They may have some ideas that could help alleviate it. ## Hi Redd, I had so much presser in my legs, had to stop xarelto, it felt like my calf's were going to bust. In a couple of days, my legs are back to normal. Pills help one thing, but ...
Updated 8 days ago.
Change from Xarelto
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I stopped Xarelto, and replaced it with Pradaxa. My back pain and headaches stopped immediately. I did have a previous back injury from years ago. I think that it's related. But it went away in days. I think that people should know. I struggled for 2 years with serious back pain and headaches. So I hope this helps everyone on Xarelto. But I must stress the previous lower back injury for a couple of years back.
Updated 10 days ago.
Playing college sports after stopping xarelto
4 Replies RSS
I'm a 21 year old, female athlete. I had surgery on my left knee (3rd one) after tearing my meniscus in December. Recovered quickly and started PT within a week after surgery. A couple months after, my calf started to swell to an abnormal size and I had pain in the back on my knee through my calf. I also started to get chest pains and dizziness. Saw a few doctors - some thought I had a Baker's cyst and didn't think the swelling was bad. Even got an EKG to rule out any heart problems, everything came back normal. It wasn't until my trainer sent me to get an ultrasound in February that they found a DVT in my femoral vein. Sent me for a CAT scan and found that it broke off and "showered" around both lungs. Immediately started me on xarelto, which gave the worst side...
Updated 11 days ago.
Xarelto and Caffeine
4 Replies RSS
I have found that I am more tired than usual and can/need sleep for extended periods since I have started Xarelto. I attempted to take caffeine pills in the morning to help me wake up only to notice after taking the caffeine pills I begun to have bleeding during bowel movements. When I stop taking the caffeine pills the bleeding really subsides to nearly non-existent. ## Hi Eric, Sorry to hear about your recent experience with bleeding during bowel movements. From what I could gather, there don't appear to be any interactions listed between caffeine and Xarelto (rivaroxaban). However, you might be surprised to know that Xarelto does actually list "bloody stools" as one of its more common side effects at: ncbi.nlm.nih.gov/pubmedhealth/PMH0045374/#DDIC603481.side_effects_secti...
Updated 11 days ago.

Possible Dosages for this and Related Drugs:

  • Tablet: 10mg, 15mg, 20mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Xarelto: (8 results)

Sorted by National Drug Code
  • 50458-578 Xarelto 15 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-579 Xarelto 20 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-580 Xarelto 10 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-584 Xarelto Kit by Janssen Pharmaceuticals, Inc.
  • 55154-1422 Xarelto 10 mg Oral Tablet, Film Coated by Cardinal Health
  • 55154-1423 Xarelto 20 mg Oral Tablet, Film Coated by Cardinal Health
  • 55154-1424 Xarelto 15 mg Oral Tablet, Film Coated by Cardinal Health
  • 69189-0578 Xarelto 15 mg Oral Tablet, Film Coated by Avera Mckennan Hospital

Other drugs which contain Rivaroxaban or a similar ingredient: (1 result)

Possibly related Xarelto Topics:

xarelto fluid retention I had to take Xarelto due to two sinus venous thrombosis in my head. 8 weeks of heparin injections showed no side effect... 147 replies
Xarelto and weight gain I have been on 15mg of Xarelto along with 40mg of Crestor for approximatley 8 months and have suffered through a distend... 53 replies
Xarelto and Vitamins? Was prescribed Xarelto 15 mg 2x daily two weeks ago for blood clot in the leg. I would like to keep taking the viamins/ ... 30 replies
Xarelto acne and weight gain I have been taking xarelto for about 4 months post PE I have gained about 20 pounds and am breaking out horribly non sto... 12 replies
Xarelto Weight Gain I just started (09/29/2016) Xarelto - 15 mg 2x/day for a large DVT and multiple PE's. In one month I have ballooned ... 9 replies
Xarelto side effects I have been taking Xarelto 15mg x2/day for almost 3 weeks and will go onto 20mg/day next week for the remainder of 3 mon... 7 replies
Xarelto and Restless Leg Syndrome I have had RLS for as long as I can remember (33yr old female). However it only affected me once maybe twice a month and... 7 replies
Xarelto and exercise and fatigue I have been on Xarelto for 4 months. I am trying to exercise but still feel so fatigued. I was very active before my DVT... 6 replies
xarelto cause leg pain burning Hi, I've been on xarelto for nearly 3 weeks. I started of with pressure & pain in the head then that went away. ... 6 replies
Xarelto and pain What can I take for pain such as headache and/or menstrual cramps? Been on Xarelto for just under a week. ## Hello, Shar... 6 replies

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