The People's Medicine Community ®


Active Ingredient(s): Rivaroxaban
FDA Approved: July 1, 2011
Category: Blood Thinner (Anticoagulant)

Xarelto Overview

Rivaroxaban (BAY 59-7939) is an oral anticoagulant invented and manufactured by Bayer; in a number of countries it is marketed as Xarelto.[1] In the United States, it is marketed by Janssen Pharmaceutica.[3] It is the first available orally active direct factor Xa inhibitor. Rivaroxaban is well absorbed from the gut and maximum inhibition of factor Xa occurs four hours after a dose. The effects last approximately 8–12 hours, but factor Xa activity does not return to normal within 24 hou...

Read more Xarelto Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Xarelto Forums: RSS Feed

xarelto fluid retention
17 Replies RSS
I had to take Xarelto due to two sinus venous thrombosis in my head. 8 weeks of heparin injections showed no side effects. But with the first day of taking Xarelto my body reacted by retaining water. Within the first three weeks I gained 24.46 lb hill exercising 5 times a week and eating as I always did. After retaining more and more water I stopped taking it after three months. I started with a weight of 120 lb at a height of 5''8 and now I weigh 157 lb. I have to ad that I started taking it in the middle of March and stopped taking it at the end of June. I was not able to loose any water/weight. I eat less than I always did before even while I exercise. All doctors couldn't find the one thing that changed through Xarelto. Has anybody ever experienced something like this wh...
Updated 8 minutes ago.
Extreme fatigue on Xarelto
10 Replies RSS
Hello, Hope someone can help. I've been hitting a wall of fatigue everyday about 1pm to the point where I need to take a 2 hour nap when my daughter is napping and its painful to wake up even after that. I take Xarelto everyday with dinner to treat a DVT. I've been on it 4 months. Is this a known side effect? I tested my theory when I started to realize this began after taking Xarelto and skipped a dose one evening. The following day I didn't need a nap and didnt have that same debilitating exhaustion. I'm only 34 this is no time to be this tired after a full nights sleep! It feels like a crash, an unnatural exhaustion. Thanks! AS ## Hi! Sorry about the problem that you're having. Unfortunately, I haven't been able to find a lot of side effect information on this...
Updated 2 days ago.
Xarelto acne and weight gain
5 Replies RSS
I have been taking xarelto for about 4 months post PE I have gained about 20 pounds and am breaking out horribly non stop especially on and around my nose occasionally have sharp pains in my arms and legs I too 15 mg twice day for first 3 weeks and now am taking 20 mg daily I seem tk be reading that 10 mg is the norm am I taking too much? I worry since this drug is so new ## Hello, Diana! How are you? Everything that you've listed can be normal side effects of it, except the break outs, I've not seen that listed anywhere. Are you on any other medications? And no, the normal doses are 15mgs twice daily or 20mgs once daily. ## I too have been suffering from acne and weight gain. I have them on my cheeks, neck and upper lip. I also have gained 12 lbs. I know my body very well and i...
Updated 2 days ago.
Xarelto and weight gain
14 Replies RSS
I have been on 15mg of Xarelto along with 40mg of Crestor for approximatley 8 months and have suffered through a distended abdomen and burning and aching in my hips, legs and feet. After blood tests and scans ruled out anything sinister I chose to stop taking Crestor altogether. Within a week my abdomen was no longer distented and much of the pain in my hips and legs reduced to a point where I actually got some sleep. I have now started back doing my walking and concentrating on eating everything right but my weight inexplicably is going up and up. I have also noticed my tension type headache and tinnitus which I have had both for 11 years has intensified and difficult to ignore. I can only think the weight gain can be caused by Xarelto...there seems to be no other explanation and I hav...
Updated 2 days ago.
Forced to stop xarelto
Post a Reply
After 4 months of being on xarelto for pulmonary embolism was taken off the med due to bleeding. I was also taken off my normal 81 mg. aspirin which I take for heart disease. Neither my hemotologist, cardiologist, nor my gastro doc, (Crohn's disease ) have suggested I take an X-ray to determine if the clots are still there. This is very vexing. I am 67, athletic, trim and eat healthy. Anyone else experience similar situations?
Updated 3 days ago.
using hormonal cream while on xarelto
Post a Reply
I just had hip surgery and forgot that I should not use a hormonal cream. I used 1 gram vaginally. Will this effect anything since I am using Xarelto
Updated 4 days ago.
xarelto and Pericardial Tissue Heart Valve
1 Reply RSS
Again, if you have an artificial heart valve (Pericardial Tissue Heart Valve) and you have an Atrial Flutter, why can you take xarelto? ## Hello, Robert! How are you? Did you mean why you can't take it? It's simply because it hasn't been studied in that patient population, so they have no way of knowing if it is safe, or not. Xarelto is classified by the FDA as a blood thinner and its typical side effects may include nausea, dizziness, headache, increased risk of bleeding, easy bruising and joint/muscle aches.
Updated 4 days ago.
Xarelto created blood in my urine and back pain
1 Reply RSS
10 mg a day and these are the side affects. My friend stopped his everyday and went to every other day and it seems to work better for him. I was thinking of doing the same thing. ## Hello, Jose! How are you doing? I'm very sorry about the problems that you're having. However, before you adjust your dosage, you should consult your doctor to make sure that it is safe for you to do so. You also need to have the blood in your urine checked out. The FDA lists the typical side effects of this medication as possibly including nausea, dizziness, headache, increased risk of bleeding, joint/muscle aches and easy bruising. What condition are you taking it to treat?
Updated 4 days ago.
Xarelto, headaches, vision disturbances
1 Reply RSS
Hi, I am wondering if anybody else has had these side effects. I had a total right hip replacement on March 2 of this year. On March 9th I went to the ER and was diagnosed with a PE in my left lung. After being there overnight I was sent home on Xarelto, two-15mg for 20 days then 15mg once a day. Three days later I went back to the ER with the most intense headache and vision distortions. If I covered my left eye and looked at the page of a book, I could see the black of the letters, but they were not distinct letter shapes, they also had shadows. There were other things also. I was in for three days, two Ct scans, a lumbar puncture, an MRI, neurologist and retina ophthalmologist, numerous blood work and they found nothing significant. Some results were slightly off so my primary is sen...
Updated 4 days ago.
Menstruation on xarelto
2 Replies RSS
My menstruation was so bad on xarelto I needed a transfusion and was taken off xarelto. When can I expect my menstrual bleeding to stop? ## Hello, Julie! How are you? I'm very sorry about the problem you had, that's terrible! Unfortunately, there's no way to be sure. As it cycles out of your body, things should return to normal, but it may take several weeks. Other side effects to stopping it, as listed by the FDA, may include headache, diarrhea and nausea. What was it replaced with? ## It was replaced with a IVC filter. No more blood thinners for me.
Updated 6 days ago.

Possible Dosages for this and Related Drugs:

  • Tablet: 10mg, 15mg, 20mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Rivaroxaban or a similar ingredient: (1 result)

Possibly related Xarelto Topics:

Xarelto and Vtamins?l Was prescribed Xarelto 15 mg 2x daily two weeks ago for blood clot in the leg. I would like to keep taking the viamins/ ... 19 replies
xarelto fluid retention I had to take Xarelto due to two sinus venous thrombosis in my head. 8 weeks of heparin injections showed no side effect... 17 replies
Xarelto and weight gain I have been on 15mg of Xarelto along with 40mg of Crestor for approximatley 8 months and have suffered through a distend... 14 replies
Xarelto acne and weight gain I have been taking xarelto for about 4 months post PE I have gained about 20 pounds and am breaking out horribly non sto... 5 replies
Xarelto and pain What can I take for pain such as headache and/or menstrual cramps? Been on Xarelto for just under a week. ## Hello, Shar... 5 replies
Xarelto and loss of strength I have been on 20mg xarelto for almost 3 months now after having a DVT come up. I am supposed to have an ultrasound at t... 4 replies
xarelto and leg and stomach pain I was on Coumadin for 7 yrs and doc offered xarelto with no testing. I've been on it a month and terrible stomach bu... 3 replies
xarelto and dairy Just started xarelto 8 days ago for dvt. I have a dairy intolerance and have begun getting esophageal spasms and stomach... 3 replies
Xarelto and Caffeine I have found that I am more tired than usual and can/need sleep for extended periods since I have started Xarelto. I att... 3 replies
Xarelto for 5 weeks. Woke up with a black eye. I started taling xarelto 5/10/2014 after my 2nd DVT in my leg. The first DVT was in February 2013 and I was on xarelto u... 3 replies