Active Ingredient(s): Rivaroxaban
FDA Approved: * July 1, 2011
Category: Blood Thinner (Anticoagulant)

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Xarelto Overview

Rivaroxaban (BAY 59-7939) is an oral anticoagulant invented and manufactured by Bayer;[3][4] in a number of countries it is marketed as Xarelto.[1] In the United States, it is marketed by Janssen Pharmaceutica.[5] It is the first available orally active direct factor Xa inhibitor. Rivaroxaban is well absorbed from the gut and maximum inhibition of factor Xa occurs four hours after a dose. The effects last approximately 8–12 hours, but factor Xa activity does not return to normal within ...

Read more Xarelto Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Rivaroxaban

Recent Xarelto Forums: RSS Feed

Cold feeling in both legs and slight shortness of breath
1 Reply RSS
My mother is 90 with AF. Last Sept had blood clots removed from rt leg. She has been on Xarelto for 8 months. She has been complaining of both legs feel ice cold. Her legs are warm to touch. She also describes twitching of her legs at night. She also has SOB when walking from one room to another. She describes it as having to catch her breath. Can this be of concern? This has been going on for months. ## Hello, Linda! How are you and your mother? There is a chance that this is due to medications side effects, the FDA does list similar symptoms as being among the possible ones it can cause, along with increased risk of bleeding, headache, nausea and easy bruising. However, given your mother's history, it would be best to have doctor check things out to be on the safe side. Is there a...
Updated 1 day ago.
Xarelto Concerns?
4 Replies RSS
Anyone concerned about the new legal cases and their allegations? Woke up the one morning with calf pain, no swelling, redness or warmth. I knew enough to know i could not explain the leg pain and was in the car for about 6 hours the previous day and decided to go to the ER. Diagnosed with a small DVT in my right lower leg. Was told to take Xarelto for 3 months. No restrictions otherwise. Back to normal activity when my leg felt better. I have been on it for 4 weeks now. Just this morning, saw various commercials in regards to the new legal cases and their allegations of the dangers of taking Xarelto... Im freaking out! Anyone else concerned? ## Hello, Debbie! How are you? There are risks associated with all medications and such claims occur frequently, whenever a new one comes to marke...
Updated 2 days ago.
hit my head while taking xarelto
5 Replies RSS
Last night my boyfriend and I were both reaching for the TV remote to shut off the TV and bumped heads pretty hard. Full disclosure: I had a few drinks. It hurt for a minute, and then I forgot about it. This morning I woke up with a dull headache, but on the opposite side of where we hit heads. I've also felt like I've been in a fog all day at work, and the dull headache has stayed, maybe even feeling more like pressure. The spot where I got hit is tender to the touch but otherwise fine. No double vision, but I notice that it's harder for me to focus on things that are close up. I have been on Xarelto 15mg twice a day for the past 2 weeks following a PE. Should I be worried? Every pamphlet etc says call your doctor if you hit your head. I don't know if bumping heads qual...
Updated 4 days ago.
Leg burning, weakness, inability to walk
3 Replies RSS
My father started on Xarelto this past week for Afib and within 2 days gradually started developing bilateral thigh, groin and buttock burning/pain progressing to inability to walk 2 additional days later and severe pain. He is normally a very active person. Has anyone experienced this? ## Hello, Greg! How is your father doing? Has there been any change? The FDA does list those types of symptoms as being possible side effects. He may also experience nausea, dizziness, headache, increased risk of bleeding and easy bruising. Side effects are typically transient and go away with time, once your body gets used to a medication, however, given the severity, I think his doctor should be informed as this may not be the right medication for him. Is there anything else I can help with? ## Hi than...
Updated 4 days ago.
These blood thinners are deadly
8 Replies RSS
Once you start taking this you will be on it until blood walls thin, then you will be begin to bleed inside, then they will make you stop taking it, and you will have a stoke or heart attack, there are many other ways to thin your blood. These blood thinner drugs are poison. They did this to my Mother and Father, and my sister as well. Please save your life and find an alternative. A natural coarse is always the best coarse of action. ## OMG THIS IS HORRIBLE POST IF TRUE.... I feel like my day and possible life is ruined from your post you better be spot on with taking the responsibility to post such a commentary. ## You didn't indicate where you got your medical degree when you posted this opinion. I have confidence in our medical system, including the prescription blood thinners t...
Updated 4 days ago.
How long does xarelto continue working in your system?
7 Replies RSS
I was on xarelto for 1month. I was taking 20 mg for a blood clot that developed from my mediport. The med caused me to itch so bad that I was switched to lovenox inj's. After three day of being on the lovenox I am still itching. It has mainly been my hands and my feet. How long do these medications work in your system for? ## Hello, Teresa! How are you? I'm sorry about the problem that you're having. If you were on the Xarelto for a month, it could take a week or so for the side effects and reaction to stop. However, you should be aware that the Lovenox could also cause itching, as a side effect, along with dizziness, headache and easy bruising. In many cases, it's due to the change it makes to your circulation. The same can occur with other medications that affect your ...
Updated 5 days ago.
Xeralto causing tightness in the head
1 Reply RSS
I'm taking 20 m strength for the last 6 weeks following a cerebral stroke. I'm having really severe tightness in my head throughout the day.Should I consult the consultant sooner than my 4 month appointment ## Hello, Brendan! How are you? I'm sorry about the problem you're experiencing. Such descriptions of symptoms and side effects can be very relative, so I'm not sure what you are referring to as tightness, but yes, if it concerns and worries you, it is always a good idea to consult your doctor. The FDA lists the typical side effects of this medication as possibly including nausea, dizziness, headache, increased risk of bleeding and easy bruising. Is there anything else I can help with?
Updated 6 days ago.
Extreme fatigue on Xarelto
18 Replies RSS
Hello, Hope someone can help. I've been hitting a wall of fatigue everyday about 1pm to the point where I need to take a 2 hour nap when my daughter is napping and its painful to wake up even after that. I take Xarelto everyday with dinner to treat a DVT. I've been on it 4 months. Is this a known side effect? I tested my theory when I started to realize this began after taking Xarelto and skipped a dose one evening. The following day I didn't need a nap and didnt have that same debilitating exhaustion. I'm only 34 this is no time to be this tired after a full nights sleep! It feels like a crash, an unnatural exhaustion. Thanks! AS ## Hi! Sorry about the problem that you're having. Unfortunately, I haven't been able to find a lot of side effect information on this...
Updated 7 days ago.
Back Pain & Joint Pain in Hips
1 Reply RSS
I'm a 49yr old female and had a DVT that caused two large lateral PE. After genetic testing and many other tests they are happy to blame the Birth control pill I was taking along with a 5 hour car ride. I am 3months on Xarelto and my side effects are back pain, hip joint pain and my sleeping is off. I have a high tolerance for pain so I have been dealing with it. I was told if all goes well with the test by my 6 month I will be released from taking Xarelto. I hope my pulmonary doctor is telling me the truth as I find him to say things he knows I want to hear. ## I am very sorry about the problems you've experienced. Those can be typical side effects of Xarelto, as listed by the FDA. You may also experience nausea, dizziness, headache increased risk of bleeding and easy bruising....
Updated 8 days ago.
Xeralto with back, joint and muscle pain
7 Replies RSS
If anyone else experienced these symptoms how long after being off the xeraltomdid symptoms go away? ## According to the US National Library of Medicine, all of the side effects you mentioned are typical of Xarelto (Rivaroxaban). They actually list "back pain" as one of the more common side effects patients experience, along with "arm/leg pain" being less common. It also goes on to list "joint or muscle pain", but declares it under a category called "incidence not known". Ref: ncbi.nlm.nih.gov/pubmedhealth/PMH0045374/#DDIC603481.side_effects_section From my perspective, I'd say the severity of these symptoms could potentially outweigh the benefits of the medication itself. Have you had a chance to sit down with your doctor and go over any of this yet?...
Updated 9 days ago.

Possible Dosages for this and Related Drugs:

  • Tablet: 10mg, 15mg, 20mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Xarelto: (8 results)

Sorted by National Drug Code
  • 50458-578 Xarelto 15 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-579 Xarelto 20 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-580 Xarelto 10 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-584 Xarelto Kit by Janssen Pharmaceuticals, Inc.
  • 55154-1422 Xarelto 10 mg Oral Tablet, Film Coated by Cardinal Health
  • 55154-1423 Xarelto 20 mg Oral Tablet, Film Coated by Cardinal Health
  • 55154-1424 Xarelto 15 mg Oral Tablet, Film Coated by Cardinal Health
  • 69189-0578 Xarelto 15 mg Oral Tablet, Film Coated by Avera Mckennan Hospital

Other drugs which contain Rivaroxaban or a similar ingredient: (1 result)

Possibly related Xarelto Topics:

xarelto fluid retention I had to take Xarelto due to two sinus venous thrombosis in my head. 8 weeks of heparin injections showed no side effect... 39 replies
Xarelto and weight gain I have been on 15mg of Xarelto along with 40mg of Crestor for approximatley 8 months and have suffered through a distend... 33 replies
Xarelto and Vtamins?l Was prescribed Xarelto 15 mg 2x daily two weeks ago for blood clot in the leg. I would like to keep taking the viamins/ ... 24 replies
Xarelto acne and weight gain I have been taking xarelto for about 4 months post PE I have gained about 20 pounds and am breaking out horribly non sto... 12 replies
xarelto and channel blockers I have afib and after ep study they put me on xarelto and diltiazem cd. The channel blocker has completely kept my heart... 5 replies
Xarelto side effects I have been taking Xarelto 15mg x2/day for almost 3 weeks and will go onto 20mg/day next week for the remainder of 3 mon... 5 replies
Xarelto and pain What can I take for pain such as headache and/or menstrual cramps? Been on Xarelto for just under a week. ## Hello, Shar... 5 replies
Xarelto Concerns? Anyone concerned about the new legal cases and their allegations? Woke up the one morning with calf pain, no swelling, r... 4 replies
Xarelto and wierd pains Perhaps one month after starting Xarelto, 20mg, I had developed a sore neck and knot in the mid knuckle of my right hand... 4 replies
Xarelto and exercise and fatigue I have been on Xarelto for 4 months. I am trying to exercise but still feel so fatigued. I was very active before my DVT... 4 replies