Active Ingredient(s): Rivaroxaban
FDA Approved: * July 1, 2011
Category: Blood Thinner (Anticoagulant)

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Xarelto Overview

Rivaroxaban (BAY 59-7939) is an oral anticoagulant invented and manufactured by Bayer;[3][4] in a number of countries it is marketed as Xarelto.[1] In the United States, it is marketed by Janssen Pharmaceutica.[5] It is the first available orally active direct factor Xa inhibitor. Rivaroxaban is well absorbed from the gut and maximum inhibition of factor Xa occurs four hours after a dose. The effects last approximately 8–12 hours, but factor Xa activity does not return to normal within ...

Read more Xarelto Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Rivaroxaban

Recent Xarelto Forums: RSS Feed

xarelto fluid retention
47 Replies RSS
I had to take Xarelto due to two sinus venous thrombosis in my head. 8 weeks of heparin injections showed no side effects. But with the first day of taking Xarelto my body reacted by retaining water. Within the first three weeks I gained 24.46 lb hill exercising 5 times a week and eating as I always did. After retaining more and more water I stopped taking it after three months. I started with a weight of 120 lb at a height of 5''8 and now I weigh 157 lb. I have to ad that I started taking it in the middle of March and stopped taking it at the end of June. I was not able to loose any water/weight. I eat less than I always did before even while I exercise. All doctors couldn't find the one thing that changed through Xarelto. Has anybody ever experienced something like this wh...
Updated 1 minute ago.
a bit of shortness of breath, and light headed ness...
2 Replies RSS
I had a PE two years ago, and was put on Xarelto, once I started my normal everyday things again and felt stronger I would sometimes get light headed and feel what could be anxiety...I stopped taking it for four moths (at a doctors advice) but then they found another clot in my deep vein near the pelvis. So back on it again...I can do lots of strenuous work and feel fine doing aqua fit etc, but sometimes when digging in the garden or just dancing a bit I get light headed and feel a shortness of breath...is this a side effect? or ? ## Those can be side effects of this medication, as reported by the U.S. FDA, along with nausea, headache, and easy bruising. However, given your history of clots, there is also a chance that something else might be going on, so you should inform your doctor a...
Updated 5 hours ago.
Extreme fatigue on Xarelto
25 Replies RSS
Hello, Hope someone can help. I've been hitting a wall of fatigue everyday about 1pm to the point where I need to take a 2 hour nap when my daughter is napping and its painful to wake up even after that. I take Xarelto everyday with dinner to treat a DVT. I've been on it 4 months. Is this a known side effect? I tested my theory when I started to realize this began after taking Xarelto and skipped a dose one evening. The following day I didn't need a nap and didnt have that same debilitating exhaustion. I'm only 34 this is no time to be this tired after a full nights sleep! It feels like a crash, an unnatural exhaustion. Thanks! AS ## Hi! Sorry about the problem that you're having. Unfortunately, I haven't been able to find a lot of side effect information on this...
Updated 6 hours ago.
can I stop taking xarelto for 3 days and resume
2 Replies RSS
I am due to have image guided injections for nerve entrapment pain in my neck and shoulders. I have been on xarelto for 8 months. Can I stay off the xarelto for 3 days to have the inj's.? I've been told by my haematologist that I have to take xarelto for life now. ## Hello, Patrick! How are you doing? Have you been instructed to stop it for a few days? If so, that is what you should do, for your own safety. Then resume taking it, after the study is done. The U.S. FDA lists its typical side effects as possibly including nausea, dizziness, headache, increased risk of bleeding, and easy bruising. ## I had to inject innohep into my stomach for 2 days prior to my image guided injections in my neck. I then had to inject a smaller dose of innohep the evening following the procedure bef...
Updated 1 day ago.
xarelto cause leg pain burning
1 Reply RSS
Hi, I've been on xarelto for nearly 3 weeks. I started of with pressure & pain in the head then that went away. Then got abdominal pain, then that went away. Then burning in my upper back that went away and now my legs have a burning sensation from my calf to foot and some muscle pain in my shoulder and arms feel like they've been bruised but no visible sign of bruising. I have a small Pe in my left lung due to child birth and the same thing happened 8 years ago due to child birth so no more kids for me. But these burning sensations in my legs and feet come and go all day and night and it's so annoying. What should I do as every time I bring this up to my doctors or hematologist they just brush me of saying it's normal. Well I'm here to say it's not normal, i...
Updated 3 days ago.
Xyralto and Botox
1 Reply RSS
Is it safe to have Botox injections while on Xyralto? Has anyone had any experience with Botox while taking Xyralto? ## Since Xarelto can increase your risk of dangerous bleeding, it is very doubtful if it is safe for you to have such a procedure. Other side effects, as listed by the FDA, may also include nausea, dizziness, headache, and easy bruising. It would be best to speak to your doctor, because before having procedures like this, you will most likely need to stop taking it for a few days. Is there anything else I can help with?
Updated 6 days ago.
How long does xarelto continue working in your system?
9 Replies RSS
I was on xarelto for 1month. I was taking 20 mg for a blood clot that developed from my mediport. The med caused me to itch so bad that I was switched to lovenox inj's. After three day of being on the lovenox I am still itching. It has mainly been my hands and my feet. How long do these medications work in your system for? ## Hello, Teresa! How are you? I'm sorry about the problem that you're having. If you were on the Xarelto for a month, it could take a week or so for the side effects and reaction to stop. However, you should be aware that the Lovenox could also cause itching, as a side effect, along with dizziness, headache and easy bruising. In many cases, it's due to the change it makes to your circulation. The same can occur with other medications that affect your ...
Updated 7 days ago.
Xarelto and joint pain
2 Replies RSS
Got one month to before my 90 days on xarelto is over. I have been experiencing severe pain in my knees, ankles, hips and elbows. Never had this pain prior to the medication. Doctor shrugged off my concerns. I really need to know if this will stop after I am done xarelto. ## Hello, Chelle! How are you doing? Has there been any change? Many people have reported experiencing various body aches and pains, while taking Xarelto, and these symptoms are listed as possible side effects in the FDA patient advisory leaflet. It may also cause dizziness, headache, increased risk of bleeding and easy bruising. However yes, such symptoms usually go away, once the medication is discontinued, but it may take a few weeks for them to fully abate. If they are really severe, you should inform your doctor, ...
Updated 9 days ago.
2 Replies RSS
Are there any side effects when getting the two together other than a risk of brusing and bleeding? ## I have posted the same question. Did you have botox while taking xyralto? If so how did it go? ## According to the University of Maryland's drug interaction tool, there are no interactions listed between Botox and Xarelto. This is not to say that no interactions exist, but based on their research it seems to me that this is not a concern. However, I would still encourage you to talk with your doctor just to get a second opinion. I'd also imagine that it may be particularly difficult to make proper discernment between each individual drug's possible side effects vs that of an interaction between the two substances...
Updated 12 days ago.
xarelto every other day instead of daily
1 Reply RSS
I have a successful cardio version 2 months ago. I take 200mg Amiodarone and 20mg xarelto daily. I am in a higher insurance tier until Jan 2017 and a 90 day supply of xarelto is $455 (I pay 45%) I don't want to stop taking xarelto but can I take xarelto every other day instead of daily? ## Hello, Ernie! How are you? You should take it as instructed by your doctor, because doing otherwise could put you in life-threatening danger. The FDA lists its typical side effects as possibly including nausea, dizziness, headache, increased risk of bleeding and easy bruising. However, given that this one is so expensive, you may want to ask your doctor about a cheaper alternative that you can try. Is there anything else I can help with?
Updated 13 days ago.

Possible Dosages for this and Related Drugs:

  • Tablet: 10mg, 15mg, 20mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Xarelto: (8 results)

Sorted by National Drug Code
  • 50458-578 Xarelto 15 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-579 Xarelto 20 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-580 Xarelto 10 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-584 Xarelto Kit by Janssen Pharmaceuticals, Inc.
  • 55154-1422 Xarelto 10 mg Oral Tablet, Film Coated by Cardinal Health
  • 55154-1423 Xarelto 20 mg Oral Tablet, Film Coated by Cardinal Health
  • 55154-1424 Xarelto 15 mg Oral Tablet, Film Coated by Cardinal Health
  • 69189-0578 Xarelto 15 mg Oral Tablet, Film Coated by Avera Mckennan Hospital

Other drugs which contain Rivaroxaban or a similar ingredient: (1 result)

Possibly related Xarelto Topics:

xarelto fluid retention I had to take Xarelto due to two sinus venous thrombosis in my head. 8 weeks of heparin injections showed no side effect... 47 replies
Xarelto and weight gain I have been on 15mg of Xarelto along with 40mg of Crestor for approximatley 8 months and have suffered through a distend... 38 replies
Xarelto and Vtamins?l Was prescribed Xarelto 15 mg 2x daily two weeks ago for blood clot in the leg. I would like to keep taking the viamins/ ... 24 replies
Xarelto acne and weight gain I have been taking xarelto for about 4 months post PE I have gained about 20 pounds and am breaking out horribly non sto... 12 replies
Xarelto reaction in my mouth I have been taking Xarelto for a month now and as soon as i take my pil, my tongue gets pimples and my lips become red. ... 5 replies
Xarelto and Restless Leg Syndrome I have had RLS for as long as I can remember (33yr old female). However it only affected me once maybe twice a month and... 5 replies
xarelto and channel blockers I have afib and after ep study they put me on xarelto and diltiazem cd. The channel blocker has completely kept my heart... 5 replies
Xarelto side effects I have been taking Xarelto 15mg x2/day for almost 3 weeks and will go onto 20mg/day next week for the remainder of 3 mon... 5 replies
Xarelto and pain What can I take for pain such as headache and/or menstrual cramps? Been on Xarelto for just under a week. ## Hello, Shar... 5 replies
Xarelto Concerns? Anyone concerned about the new legal cases and their allegations? Woke up the one morning with calf pain, no swelling, r... 4 replies