Active Ingredient(s): Rivaroxaban
FDA Approved: * July 1, 2011
Category: Blood Thinner (Anticoagulant)

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Xarelto Overview

Rivaroxaban (BAY 59-7939) is an oral anticoagulant invented and manufactured by Bayer;[3][4] in a number of countries it is marketed as Xarelto.[1] In the United States, it is marketed by Janssen Pharmaceutica.[5] It is the first available orally active direct factor Xa inhibitor. Rivaroxaban is well absorbed from the gut and maximum inhibition of factor Xa occurs four hours after a dose. The effects last approximately 8–12 hours, but factor Xa activity does not return to normal within ...

Read more Xarelto Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Rivaroxaban

Recent Xarelto Forums: RSS Feed

xarelto fluid retention
41 Replies RSS
I had to take Xarelto due to two sinus venous thrombosis in my head. 8 weeks of heparin injections showed no side effects. But with the first day of taking Xarelto my body reacted by retaining water. Within the first three weeks I gained 24.46 lb hill exercising 5 times a week and eating as I always did. After retaining more and more water I stopped taking it after three months. I started with a weight of 120 lb at a height of 5''8 and now I weigh 157 lb. I have to ad that I started taking it in the middle of March and stopped taking it at the end of June. I was not able to loose any water/weight. I eat less than I always did before even while I exercise. All doctors couldn't find the one thing that changed through Xarelto. Has anybody ever experienced something like this wh...
Updated 3 minutes ago.
Stopping Xarelto
40 Replies RSS
I have been instructed to stop my 20mg a day after being on it for 6 months (2 PE's one in each lung at Xmas) and I have to say I am really worried and every little pain I think its come back. I have another 3 weeks to go until I got for a blood test to see if I am prone to clots however I am completely paranoid. Anyone else had the same feelings....as the meds have been my comfort blanket for so long..... ## Have you had a hypercoagulability test? Mine revealed a Factor B Leiden gene mutation, so I will never stop taking blood thinners. If you can have that blood test, it will let you know if you have a tendency to clot. ## Do you mean Factor V Leiden? Been on 20 mg Xarelto since march 2014. Had double pneumonia in jan 2014 accompanied by DVT which threw clots to my lungs. In hospt...
Updated 3 days ago.
Pulmonary Embolism
1 Reply RSS
Hi there, I am a 40 year old woman, recently had cramps in my left calf and shortness of breath. Went to the physician and was hospitalized for blood clots having ran from my calf to my lungs. I am on Warfarin, but my doctor recommended Xarelto for the next three months. I have read so many reviews and came across legal cases against the company as there is no antidote. I'm so scared, should I continue with Warfarin then? ## Hello, Yusra! How are you? It's up to you, really. Though some people have had trouble with Xarelto, many have taken it without a problem. The U.S. FDA lists its typical side effects as possibly including nausea, dizziness, headache, increased risk of bleeding and easy bruising, so very similar to Warfarin. Can anyone that's taken Xarelto chime in with t...
Updated 7 days ago.
Xarelto and spinal stroke?
2 Replies RSS
Has Xarelto caused you to have a spinal stroke? ## Hello, Ann! How are you? Xarelto has been known to cause many types of bleeding and strokes in various parts of the body, though spinal is not specifically mentioned, the FDA does warn about possible bleeding issues and stroke in general. Other side effects may include dizziness, headache and nausea. Does you doctor think it caused this to happen to you? ## Yes, he thinks that's a strong possibility. I'm still having diagnostics done to determine the cause of my problem. I go for a second opinion next week with another neurologist. I have been taking Xarelto since last August. This drug has scared me ever since I started it after being diagnosed with Afib. I have an appt with my cardiologist next month and I plan to insist he pu...
Updated 12 days ago.
Vivid dreams and nightmares
2 Replies RSS
Hi all, I have been taking Rivaroxaban (UK name for Xarelto) since November 2015 and I have a number of issues, most of which have been mentioned on here already, like joint pain and fatigue but on thing I don't see anyone else mention is having seriously vivid dreams, to the point where I wake up in a sweat and breathing rapidly with a fast heart rate too. Some dreams are quite violent or a bit gory, like I was being chased by Russians (FFS)! A few nights ago I dreamt I was picking hard skin off my feet, but the whole of the sole of my foot came away leaving raw red flesh! I cannot be alone, surely??? ## This medication has been known to cause sleep disorders and almost any medication risks causing vivid dreaming, so it's not really unusual. Other side effects, as listed by the...
Updated 13 days ago.
Extreme fatigue on Xarelto
19 Replies RSS
Hello, Hope someone can help. I've been hitting a wall of fatigue everyday about 1pm to the point where I need to take a 2 hour nap when my daughter is napping and its painful to wake up even after that. I take Xarelto everyday with dinner to treat a DVT. I've been on it 4 months. Is this a known side effect? I tested my theory when I started to realize this began after taking Xarelto and skipped a dose one evening. The following day I didn't need a nap and didnt have that same debilitating exhaustion. I'm only 34 this is no time to be this tired after a full nights sleep! It feels like a crash, an unnatural exhaustion. Thanks! AS ## Hi! Sorry about the problem that you're having. Unfortunately, I haven't been able to find a lot of side effect information on this...
Updated 20 days ago.
These blood thinners are deadly
9 Replies RSS
Once you start taking this you will be on it until blood walls thin, then you will be begin to bleed inside, then they will make you stop taking it, and you will have a stoke or heart attack, there are many other ways to thin your blood. These blood thinner drugs are poison. They did this to my Mother and Father, and my sister as well. Please save your life and find an alternative. A natural coarse is always the best coarse of action. ## OMG THIS IS HORRIBLE POST IF TRUE.... I feel like my day and possible life is ruined from your post you better be spot on with taking the responsibility to post such a commentary. ## You didn't indicate where you got your medical degree when you posted this opinion. I have confidence in our medical system, including the prescription blood thinners t...
Updated 27 days ago.
Xarelto and side effects versus when to stop...
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I had arthroscopic surgery on my Rt. Knee (meniscus) back on Sept.29, 2015. I am 48, non-smoker, non-drinker and had this same surgery for Miniscus tear prev. 8 yrs. ago. No issues 8 yrs ago on first surgery, but this past one from Sept. 2015- Bingo, all the symptoms and issues when my Rt calf began to swell. I had ortho appt on Oct. 21, 2015, and dr. said he feared a clot. He sent me directly to have an ultrasound, and wow I had 4 clots- 2 in upper leg and 2 in lower calf. I couldn't believe it. I was told to go to ER and I did- Herparin city- they started an IV and began pumping via a syringe- Heparin into my IV. Er doc said he needed to get a CT scan of my chest- suspecting clots in lungs and Bingo again-- 3 clots in my lungs- one on each lower lobe of lung, but biggest concern w...
Updated 30 days ago.
Cold feeling in both legs and slight shortness of breath
1 Reply RSS
My mother is 90 with AF. Last Sept had blood clots removed from rt leg. She has been on Xarelto for 8 months. She has been complaining of both legs feel ice cold. Her legs are warm to touch. She also describes twitching of her legs at night. She also has SOB when walking from one room to another. She describes it as having to catch her breath. Can this be of concern? This has been going on for months. ## Hello, Linda! How are you and your mother? There is a chance that this is due to medications side effects, the FDA does list similar symptoms as being among the possible ones it can cause, along with increased risk of bleeding, headache, nausea and easy bruising. However, given your mother's history, it would be best to have doctor check things out to be on the safe side. Is there a...
Updated 1 month ago.
Xarelto Concerns?
4 Replies RSS
Anyone concerned about the new legal cases and their allegations? Woke up the one morning with calf pain, no swelling, redness or warmth. I knew enough to know i could not explain the leg pain and was in the car for about 6 hours the previous day and decided to go to the ER. Diagnosed with a small DVT in my right lower leg. Was told to take Xarelto for 3 months. No restrictions otherwise. Back to normal activity when my leg felt better. I have been on it for 4 weeks now. Just this morning, saw various commercials in regards to the new legal cases and their allegations of the dangers of taking Xarelto... Im freaking out! Anyone else concerned? ## Hello, Debbie! How are you? There are risks associated with all medications and such claims occur frequently, whenever a new one comes to marke...
Updated 1 month ago.

Possible Dosages for this and Related Drugs:

  • Tablet: 10mg, 15mg, 20mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Xarelto: (8 results)

Sorted by National Drug Code
  • 50458-578 Xarelto 15 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-579 Xarelto 20 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-580 Xarelto 10 mg Oral Tablet by Janssen Pharmaceuticals, Inc.
  • 50458-584 Xarelto Kit by Janssen Pharmaceuticals, Inc.
  • 55154-1422 Xarelto 10 mg Oral Tablet, Film Coated by Cardinal Health
  • 55154-1423 Xarelto 20 mg Oral Tablet, Film Coated by Cardinal Health
  • 55154-1424 Xarelto 15 mg Oral Tablet, Film Coated by Cardinal Health
  • 69189-0578 Xarelto 15 mg Oral Tablet, Film Coated by Avera Mckennan Hospital

Other drugs which contain Rivaroxaban or a similar ingredient: (1 result)

Possibly related Xarelto Topics:

xarelto fluid retention I had to take Xarelto due to two sinus venous thrombosis in my head. 8 weeks of heparin injections showed no side effect... 41 replies
Xarelto and weight gain I have been on 15mg of Xarelto along with 40mg of Crestor for approximatley 8 months and have suffered through a distend... 33 replies
Xarelto and Vtamins?l Was prescribed Xarelto 15 mg 2x daily two weeks ago for blood clot in the leg. I would like to keep taking the viamins/ ... 24 replies
Xarelto acne and weight gain I have been taking xarelto for about 4 months post PE I have gained about 20 pounds and am breaking out horribly non sto... 12 replies
xarelto and channel blockers I have afib and after ep study they put me on xarelto and diltiazem cd. The channel blocker has completely kept my heart... 5 replies
Xarelto side effects I have been taking Xarelto 15mg x2/day for almost 3 weeks and will go onto 20mg/day next week for the remainder of 3 mon... 5 replies
Xarelto and pain What can I take for pain such as headache and/or menstrual cramps? Been on Xarelto for just under a week. ## Hello, Shar... 5 replies
Xarelto Concerns? Anyone concerned about the new legal cases and their allegations? Woke up the one morning with calf pain, no swelling, r... 4 replies
Xarelto and wierd pains Perhaps one month after starting Xarelto, 20mg, I had developed a sore neck and knot in the mid knuckle of my right hand... 4 replies
Xarelto and exercise and fatigue I have been on Xarelto for 4 months. I am trying to exercise but still feel so fatigued. I was very active before my DVT... 4 replies