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Category: Asthma

Welcome to the Mepolizumab information hub. Scroll down to read supplemental details and discuss this drug.

Mepolizumab Overview

Mepolizumab (proposed trade name Bosatria) is a humanized monoclonal antibody that recognizes interleukin-5 (IL-5), and is used to treat certain kinds of asthma and white blood cell diseases. Recent studies have concluded that mepolizumab may improve exacerbations in patients with severe eosinophilic asthma, an adult-onset asthma which represents less than 5% of all asthma. IL-5 is a chemical messenger in the immune system that stimulates the growth of eosinophils. In eosinophilic asthma, eos...

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Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

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Hypereosinophilic syndrome treatment
I have had HES for 12 years and want to trial Mepolizumab. My specialist has been unable to get me on a trial. What avenues do I have? ## It is really entirely up to the criteria set by the testing agencies and manufacturer, if they don't think you fit the patient profile, then they have the right to refuse you from their clinical trials and, unfortunately, you have no recourse in most countries. It's not the same as if someone were denying you a treatment options that has actually been proven to be life-sustaining. What reason did they give for not letting you into the trials? ## Thanks for your reply Verwon. In a nutshell, I didn't qualify for the trial because my death is not imminent. I have some control using hydroxyurea although the side effects depress all blood cell ...
Updated 1 year ago.
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