Active Ingredient(s): Vismodegib
FDA Approved: * January 30, 2012
Pharm Company: * GENENTECH
Category: Cancer

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Erivedge Overview

Vismodegib (trade name Erivedge) is a drug for the treatment of basal-cell carcinoma (BCC). The approval of vismodegib on January 30, 2012, represents the first Hedgehog signaling pathway targeting agent to gain U.S. Food and Drug Administration (FDA) approval.[1] The drug is also undergoing clinical trials for metastatic colorectal cancer, small-cell lung cancer, advanced stomach cancer, pancreatic cancer, medulloblastoma and chondrosarcoma as of June 2011[update].[2] The drug was developed ...

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Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Erivedge Forums: RSS Feed

Erivedge is chemo?
2 Replies RSS
Is Erivedge classified as chemotherapy? If I lose my hair will it be permanent, even if I stop the medication? ## Hello, Sheilah! How are you? Yes, it is classified as a cancer medication that is used to treat basal cell carcinoma that has spread to other parts of the body. And yes, side effects generally reverse, once the course of treatment is completed. Other possible side effects, as listed by the FDA, may possibly include nausea, dizziness, weight loss, joint pain and diarrhea. Is there anything else I can help with? ## What can I do about the DEBILITATING muscle cramps????? Some days I can't ewven move without triggering these terrible cramps!
Updated 9 minutes ago.
Prospective patient
2 Replies RSS
My MOHS surgeon, my oncologist, my neck surgeon at University Miami School of Medicine Hospital all suggest Erivedge, but are not patients themselves and have limited experience. 78, 40 years of Basal cancers, denial, new nose. Now have bleeder spots on the nose and won't have more surgery. Are Erivedge side effects life style changing? I would like to talk to other patients. {edited for privacy} ## Hello, Jim! How are you? I've not taken it, but I can provide you with information on the side effects, as provided by the FDA. It is most commonly used to treat BCC and its typical side effects are listed as possibly including nausea, vomiting, diarrhea, decreased appetite, joint pain, muscle spasms, weight loss and decreased sense of taste. Can anyone that's taken it chime in? ...
Updated 3 months ago.
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Preciso comprar o erivedge,alguém sabe onde encontro?
Updated 1 year ago.
My Son is taking Erivedge for 4 months
10 Replies RSS
My son has been taking Erivedge for 4 months. His facial hair, eyebrows re thinning. His hairline is receeding. I have heard some people take this medicine for 6 months and off 6 months. I am afraid if he stays on it full time -- he will loose all of his body hair and I am afraid of what this will do him. I have heard people on Chemotherapy take 5,000mcg Biotin. Has anyone tried this to help counteract the affects of hair loss. Would taking this medicine for 3 months on and 3 months off help to couteract the affects of hair loss while keeping the cancer at bay? ## Hair loss can be a very common side effect of Erivedge, but what you really have to consider is which is worse, the temporary hair loss, or letting the cancer be out of control? Learn more Erivedge details here. As to cycling ...
Updated 1 year ago.
Erivedge or Surgery?
1 Reply RSS
I have an ever increasing number of BCC's, treated by surgery and PDT. The last one under the eyelid. I have an increasing fear that one will go un noticed and cause death or mutilation. I am being offered a course of Erivedge which appears to have really bad side effects,which, with Gorlin's Syndrome means a lifetime of treatment. I also have Parkinson's, which means a pretty low llifestyle without the addition of Erivedge Any advice? ## Hello, Ferneyberger! How are you doing? I am very sorry about the problem that you're having. The side effects for Erivedge aren't really any different than those for other similar treatment drugs and the most common ones experienced were actually fairly milked and included nausea, diarrhea, muscle spasms, fatigue and hair loss. Whi...
Updated 1 year ago.
nausea now?
1 Reply RSS
I am almost 3 months into a 12 month plan of Erivedge. I have been really nauseated the last few days. Throwing up and diarrhea. I have had only muscle cramps up until this point. Trying to figure out if its a stomach virus or the medication. Would it take this long for nausea to set in? ## Yes, usually nausea as a side effect of a medication would hit very quickly and not take several months to manifest. Learn more Erivedge details here. Have you checked in with your doctor? Odd things can happen with some medications and how they affect different people, so it's best to have things checked out to be sure.
Updated 2 years ago.
Continue to work.
7 Replies RSS
I am starting a 10 month program for BCC, and I have a physically demanding job, with a lot of traveling involved. Will I still be able to work and travel while taking this medication? ## This contains the active ingredient Vismodegib and it is very new to the market, having only been approved at the end of January of this year. Thus, this type of information isn't available, yet. Learn more Vismodegib details here. This often happens when drugs are new to be approved, because no one has used them under real world conditions, such as working in such a manner. Have you discussed it with your doctor? How severe is your BCC? ## Started with the medication 7th July, and untill now I feel some small differences in my body-balance, but not that much that blocks it me in my daily work. The...
Updated 2 years ago.

Possible Dosages for this and Related Drugs:

  • Capsule: 150mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Erivedge: (1 result)

Sorted by National Drug Code
  • 50242-140 Erivedge 150 mg Oral Capsule by Genentech, Inc.

Other drugs which contain Vismodegib or a similar ingredient: (1 result)

Possibly related Erivedge Topics:

Erivedge is chemo? Is Erivedge classified as chemotherapy? If I lose my hair will it be permanent, even if I stop the medication? ## Hello,... 2 replies
Erivedge or Surgery? I have an ever increasing number of BCC's, treated by surgery and PDT. The last one under the eyelid. I have an incr... 1 reply
erivedge Preciso comprar o erivedge,alguém sabe onde encontro?...
My Son is taking Erivedge for 4 months My son has been taking Erivedge for 4 months. His facial hair, eyebrows re thinning. His hairline is receeding. I have h... 10 replies