Contrave

Active Ingredient(s): Bupropion Hydrochloride + Naltrexone Hydrochloride
FDA Approved: * September 10, 2014
Pharm Company: * OREXIGEN THERAPEUTICS INC
Category: Diet / Weight Loss

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Contrave Overview

Bupropion/naltrexone is a combination drug treatment for obesity.[1][2] It combines bupropion and naltrexone. Both drugs have individually shown some evidence of effectiveness in weight loss, and the combination is expected to have a synergistic effect.[3] In September 2014, a sustained release formulation of the drug was approved for marketing in the United States under the brand name Contrave.[1] The combination was subsequently approved in the European Union in the spring of 2015, where it...

Read more Contrave Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Bupropion/naltrexone

Recent Contrave Forums: RSS Feed

wanting to quit taking contrave
89 Replies RSS
I need to know how to stop taking contrave. Can I just quit cold turkey or do I wean off? If I wean off how do I do it? ## Hello, Janice! How are you? How long have you been taking it? Why do you want to stop it? The FDA lists Contrave as being used to aid in weight loss and its typical side effects may possibly include nausea, dizziness, nervousness, insomnia and anorexia. Have you consulted your doctor? It does require slow tapering for some people. ## I was looking up how to wean myself off of Contrave and found this comment on here. I've been taking Confrave for about a month or so. I just started the 2 pills in the morning and 2 pills at night dose Sunday (today is Friday). I've felt horrible all week since increasing it. Hot flashes in my face, horrible nausea, glands some...
Updated 9 minutes ago.
 
Contrave-losing effect
3 Replies RSS
I am on my 4th week with Contrave and feel great. I have only lost 3lbs and now I'm noticing my appetite returning...is it loosing its effect? I take 4 pills daily. The pharmacist was no help and said that will happen with any medication. Anything I can do to loose that appetite again? Thanks! ## I feel this too! I feel like my cravings are coming back. Do I have to keep upping the dosage bc I don't want to do that and shouldn't have to. ## Many people have reported hitting a plateau with this medication, which may last for a few weeks, according to NIH reports. Other side effects as listed as possibly including nausea, dizziness, headache, and anorexia. If you are still seeing no improvement after about a month, or so, you should inform your doctor. How are you both doing? ...
Updated 1 day ago.
 
Side effects of Contrave
4 Replies RSS
I'm on my third day. Today I have a severe headache. But my question is this, has anyone had bad diarrhea? I get cramps, then bam. But I was feeling better by night. Today is the worst. Should I continue or stop? ## Hello, Shercon! How are you doing? I'm very sorry about the way you're feeling. Those can be normal side effects of Contrave and it may take about a month for them to wear off, as your body gets used to the medication. Other side effects, as listed by the FDA, may possibly include dry mouth, dizziness and nausea. Have you consulted your doctor? Unless they feel there is some reason to be concerned, you should most likely continue taking it. ## Verwon -- are you taking Contrave? ## I'm on Contrave and the stomach discomfort wore off, very mild headache left to...
Updated 1 day ago.
 
Contrave and suboxone
27 Replies RSS
I started today with my first dose of contrave, 1 pill in the AM. I also take suboxone 8mg (4 1 time a day). My doctor stated that the interaction of the two should be minimal..yeah NO! I got diarrhea, hot flashes, chills, body aches, and pretty much every withdrawal symptom known to man. I now dont want to take the contrave because I am not ready to stop the suboxone. Should I just stop the contrave and continue the sub? Or how should I go about this? ## Hello, Kiat! How are you? I'm very sorry about what happened. Yes, the Naltrexone in Contrave can cause you to go into withdrawal from any opiate, as listed by the FDA, and you were doubling it up with the Naloxone in the Suboxone that does that same thing. As to how to continue, it usually takes about 3 days, before you can safely...
Updated 1 day ago.
 
Can eating high fat meals while taking Contrave cause a seizure?
4 Replies RSS
I had Dunkin donuts english muffin sandwich with burger king's small hashbrowns and a small sweet tea (dunkin donuts). Contrave says no high fat meals .. So is it safe to take my one pill now ? Or should I give it an hour, eat a Banana then take it ? I definitely don't want to have a seizure! I'm freaking out. ## It's actually hard to say, but yes, there is a risk of them occurring. The higher the dose of Bupropion, the greater the risk of experiencing a seizure.. a high amount of fat may cause your body to retain higher amounts of Bupropion, which in turn, could potentially cause you to experience a seizure, as reported under the FDA provided potential side effects. While it most likely contains sugar, the sweet tea most likely did not contain any fat, unless they did s...
Updated 2 days ago.
 
Contrave - restarting and side effects
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I've been taking Contrave for about 2 1/2 months. During week 6 or so I was hospitalized with a severe UTI and kidney infection (4 days). The hospital wouldn't give me Contrave during my stay but I resumed when I got home by taking 1 pill a day for a week, then back to the normal doesage of 4/day. I am not noticing any benefits from the Contrave now. 1. I'm wondering if the UTI was a side effect of the Contrave (it's listed as a possible side effect) and 2. Why am I not having any of the benefits? How do I get back to losing?
Updated 2 days ago.
 
Not yet adjusting to Contrave
40 Replies RSS
Into my second month on contrave. I have experienced every side effect. Irritable, ringing ears, vomiting, lack of libido ect..ect. I have lost weight but at a high price. I hope hope hope my body will adjust to this torture. ## You should try Belviq, it has a much friendlier side effect profile ## @Jojo, I'm not sure how long it's supposed to take for your body to adjust to the effects of Contrave, but after two months of it not working as expected I'd be hard pressed to expect anything different out of it. That's just me though. I realize some medications such as birth control can also take a long time to become fully effective as well; and if that is the case with Contrave this may just be an extended waiting game. However, on the other hand - if the side effects aren...
Updated 3 days ago.
 
how long does it take to get contrave out of your system
8 Replies RSS
I need to reduce my intake of Contrave because of side affects. I'm cutting back from 4 pills to 3. How long does it take for Contrave to reduce in my system so that I don't have the severe symptoms? ## Hello, Penni! How are you feeling? Has there been any improvement, yet? What side effects have you been experiencing? When it comes to this medication, it depends on which ingredient is causing the symptoms. The Naltrexone in it only takes about a day, but the Bupropion may take about a week, based on the FDA listed half-lives. ## I saw my doctor yesterday. We have reduced my dosage to 2 pills a day to see if that helps. If not than next week I'll go down to 1 a day. My worst symptoms out of several are hot flashes & nausea. ## I've only been taking contrave for a wee...
Updated 3 days ago.
 
Help for constipation while on contrave
4 Replies RSS
Please advise. I'm day 3 off contrave and constipation has set in! What do you all use to ease constipation? ## I drink room temperature organic prune juice every morning. I had an extreme bout of constipation before until I took a laxative then used prune juice later in the day because the constipation was coming back. Haven't had much problems now with constipation if I drink some in the morning to get everything moving from my system from the night before. ## I have taken Contrave for one week and have had constipation. I must admit that I have not been drinking enough water though. I started taking stool softeners every day, from one to three daily. I've had bouts of constipation in the past, and my gastroenterologist said it is safe to take stool softeners daily. I did ...
Updated 4 days ago.
 
contrave and sleepiness
39 Replies RSS
I started contrave 4 days ago, today being my 5th dose. every day, i take the pill about 8am and by 9:30-10am I am so sleepy I can't stand it. Days 1 and 2 I managed to fight it off until about 12-12:30, day 3 until about 1-1:30, and day 4 I fought it off until 3pm. If I take a 1-2 hour nap, I wake up fine, with energy and then cannot get to sleep until about 2am, sometimes 3am. Today is day 5, I'm having that "drunk" feeling and sleepy, but no where near how it has been. It seems this effect is slowly wearing off, but I haven't seen anywhere where this is a common side effect. I know all medications effect everyone differently, so I'm wondering if this is something I should be concerned about, or just another side effect that I will get used to as the weeks go o...
Updated 5 days ago.
 

Possible Dosages for this and Related Drugs:

Bupropion Hydrochloride + Naltrexone Hydrochloride
  • Tablet, Extended Release: 8mg + 90mg, 90mg + 8mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Contrave: (2 results)

Sorted by National Drug Code
  • 50090-2868 Contrave Oral Tablet, Film Coated, Extended Release by A-s Medication Solutions
  • 64764-890 Contrave Oral Tablet, Film Coated, Extended Release by Takeda Pharmaceuticals America, Inc.

Drugs with one or more similar ingredients: (5 results)


Possibly related Contrave Topics:

Contrave vs Belviq I was on free 2 weeks of Belviq followed by 1 mo out of pocket Belviq. Lost and felt good with NO side effects at all. T... 61 replies
contrave and sleepiness I started contrave 4 days ago, today being my 5th dose. every day, i take the pill about 8am and by 9:30-10am I am so sl... 39 replies
Contrave and alcohol consumption I have filled my prescription of Contrive but have not yet started taking it. I read all the possible side effects and a... 30 replies
Contrave and suboxone I started today with my first dose of contrave, 1 pill in the AM. I also take suboxone 8mg (4 1 time a day). My doctor s... 27 replies
Contrave / ringing in ears Has anyone suffered from ringing in ears from Contrave? I'm going insane :(. but losing weight :) ## Hello, Jojo! Ho... 23 replies
Contrave and High Fat Foods I ate a high fat meal (stuffed baked potato) tonight and am wondering when it is safe to take my evening dose of Contrav... 18 replies
Contrave and appetite control I'm currently on week 3 of Contrave (2 pills in the AM/1 in the PM). When should I possibly be noticing a decrease i... 9 replies
contrave and cymbalta On day two of Contrave but also on 30mg of cymbalta. My doctor didn't seem to have any worries on both together. Has... 8 replies
Contrave and Vomiting I have been on Contrave for 3 months. I have battled nausea all along, hoping it would go away. I've lost 15 pounds.... 7 replies
Contrave Evening Dose I'm starting my 2nd week on Contrave tomorrow and the prescription says to take 1 in the morning and one in the even... 5 replies



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