Opana 40mg Vs Oxycontin Op 80mg (Page 9)

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my Dr prescribed Opana 40mg as alternative to Oxy 80 mg 2 twice a day which I would insufflate - I didn't tell him this of course. he claimed them to be just as good if not stronger can any one share about opana 40mg

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161

I completely 100% agree... I have a cyst in my spinal cord, two ribs removed due to Thoracic Outlet Syndrome, complex Regional Pain Syndrome... Due to being in the hospital, as the doctors tried to figure out what to do w/blockages in my collar bone area ( purple hand, pain, tingling, stabbing, burning, numbness, & extreme muscle spasms... For the last 15yrs and still meds, Meds, Meds. I'm here in VT & yes taking more than 5 of the new Op's made me sick, I've lost 35lbs.. Weighting 120-5'6"... And with obvious pain/anxiety/depression they have not touched the dosages on pain meds & Klonipin I was proscribed 1mg 3x a day... But the Doctors dont understand,bouncing me from doc to doc, I go w/no help. Because being out if pain is a privilege not a right, they say.. I'm bedridden ex-pro Ballet Dancer bedridden and they have screwed w/my meds... Saying the Klonipin is too much si Beta -blockers I go.. Fletcher Allen Heath care... Btw is responsible for lumps in my neck, not checking my lungs in 3months now... I don't know what to do, no one will help. I'm independent but I'm giving up any hope as I can't feel my hands as I write this.

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162

Dear, john- # 142, posted 7/26/11 - Taking either large or small amounts of pain killers does not make a person a drug addict. Becoming hooked is very rare. Taking pain meds for long periods of time can make one, Opioid Dependent. Speak to your DR.!

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163

Joey, keep on snorting them narcotics and you will definately be dead soon. Hell, you've more than likely shortened your life span anyway. These types of meds are made for swallowing, not snorting.

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164

Gunney, telling people that by taking narcotics for any amount of time means that they are addicted - that is the stupidest thing I've ever heard. People that have taken narcotics for a long time , or that take large amounts of them OPIOID TOLERANT. Which is so very different than being addicted.

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165

Dear Brazilian Baby, you don't know much about religion or its Demographics. The Christian Religion encompasses approximately 80% of the Worlds Religion. That is Big 8, Big 0 , together. 80%, Wow!!!

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166

don't give up I know exactly what you are going through. Somehow you need to fine a doctor who will listen too you like I did. I got screwed over by a very large medical center here in Pa. Hershey. they didn't listen to another facility tell them that I had RSD instead they just pumped med after med into me which either made me sick or did nothing. I finally found a doctor they call the "TRASH CAN DOCTOR" because he gets all the crap no other doctor wants or understands. Even though I'm dying he has given me back a major part of my life so I can at least work and have some enjoyment in life. Hell girl come up here to Pa. and i'll put you in touch with my doctor. Seriouly let me know I will help you.

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167

Scott, not to get too off topic here but I think your statistic about world religions is slightly inaccurate. For example, wikipedia states that while Christianity is the most followed religion in the world, it only accounts for 2 to 2.2 billion people in the world. Islam is in second place with 1.57 to 1.65 billion followers. [1] And the list has 18 entires below the top two ... so 80% ... really? Sorry I have to disagree.

And sorry to everyone else who had to deal with my off-topic post. Relating to this thread a bit more I do have to bring up the controversial question of what constitutes a drug addict? Is it more of a "moral" stance being taken, or can a legitimate patient whose body becomes physiologically addicted to an opiate medication be considered an addict?

Personally, I do not think badly of those individuals. Either (A) They were prescribed a terribly addictive drug to cope with severe pain from an injury or neurological condition or (B) Poor souls who got to a point in their lives where coping with everyday stuff became unbearable.

I know I'm generalizing here and I'm sorry for doing that. And I'm sure that many of you will not agree with what I've said above ... however ... I do feel that nobody knows what someone else is going through, so judging them is fruitless. If you had to walk a mile in their shoes then you would probably end up where they are, metaphorically speaking. The key to healing others is COMPASSION not judgement. There are not enough programs out there which make compassion their #1 prerogative. If there were then there would be far less "addicts"!

Peace out

[1] Wikipedia - Major_religious_groups #Largest_religions_or_belief_systems_by_number_of_adherents

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168

HI
I WAS WONDERING WHAT STATE YOUR IN?
I AM ALSO ON OPANA BUT I LIVE IN KENTUCKY AND IN
THE PROCESS OF LOOKING FOR A PAIN CLINIC OR DR. THAT WILL CONTINUE ME ON THEM. MOST OF THE CLINICS HERE ARE GOING TO SHOTS ONLY. I've DONE THE SHOTS AND THEY DON'T PROVIDE ME WITH ANY RELIEF. I HAVE NO IDEA HOE TO GO ABOUT FINDING A DOCTOR. I HAVE MY M.R.I'S ECT. CAN YOU GIVE ME ANY ADVICE? THANK YOU

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169

YES THEY WORK GREAT. THE PROBLEM IS FINDING AND KEEPING A DOCTOR THAT WILL PRESCRIBE THEM TO YOU.
IT'S GETTING HARDER BECAUSE THE DRS ARE AFRAID TO WRITE SCRIPST FOR THEM.

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170

EXPENSIVE----- YES OPANA $800.00 for thirty days I just found out I have only workmans comp they approved to pay it and the pharmacy will not order to expensive I dont get it Im pissed because this sounds like a life saver. Ive been in massive pain for a yr and half tried it all except oxy. Iam a 38 yr old female. I have a wonderful pain DR in OR and he is moving to Texas. I hope I get refered to another great DRI also have RA so I have very little get up and go. I miss the days that were normal just NORMAL.Im depressed no quaulity of life. YES Im a horrible speller lol. As for junkies all of us that are on these types of meds are all addicts I do belive there are differant types some recreational and some due to a painful life but at the end of the day we are all humans and if we dont have oneanother to rely on what do we have. We all can learn something from oneanother. Just my thoughts and how I feel. Love this sight I have learned so much. TY to all of you keep it up. Bless all and Peace and Love to all....I hope your journey is the best it can be while we are here on this earth I pray all to be painfree and not addicted on this earth. Bless you and yours on your journey

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171

I'd like to start by saying that i am honestly astonished at how many of you either have NO idea what drugs you are taking, whats in them, how they work ect, or are just grossly misinformed by other on this forum. First of id like to just clear up basic misunderstanding and ignorance of basic opiate painkiller.
Natural Opiates= Codeine, Morphine; these are drugs that are found in small percentages naturally in the opium poppy.
Morphine comes in many different forms. MS Contin is Morphine Sulfate Contin, the contin simply means that it is a sustained release medication that will release the medication slowly throughout the day. Other forms are just plain morphine that is released immediately. Names like Kadian, and Avenzia are just the names of pharm companies and different fomulations of the same morphine.
Hydrocodone: Vicodin, Vicoprofen, Norco. is roughly 1/2 the strength of oral morphine with 17mg being equivalent to 10mg oral morphine.
This is the most commonly prescribed narcotic painkiller. Comes in a variety of combinations with Tylenol (paracetamol) and Ibuprofen, from 5mg/325mg-7.5/750mg. When the dosage of actual hydrocodone is 10mg the pills are called Norcos instead of Vicodin.

Hydromorphone: Dilaudid, Palladone, ect. Semi-Synthetic opiate, roughly 5x the potency of Morphine, with 2mg being equivalent to 10mg of oral morphine. Although its potency if markedly stronger than morphine it has the draw back of very poor bioavailability when taken orally, about 30-35%. This improves with other routes of administration, intranasal administration (snorting) improves bioavailability to about 45-60%. If anyone has ever had the pleasure of IV hydromorphone in the hospital (or otherwise) will know that this by far the BEST route of administration, the rush is so intense some find it uncomfortable, very novel opiate. The 1,2,4, and 8mg IR pills are novel among opiate painkillers in that they contain the least amount of binder/filler in proportion to the actual amount of Hydromorphone making them well suited for illicit injection.

Oxycodone: Oxycontin, Roxicet, Roxicontin, Percocet, Percodan. Synthetic Opiate roughly 1.5-2x the potency of morphine with 5-6.5mg being equivalent to 10mg of oral morphine. Comes in a variety of formulations, when combined with aspirin it is called Percodan, when combined with Tylenol it is called Percocet. It also comes in the Instant Release formula containing only Oxycodone and as the Contin formula which is SUPPOSED to provide 12 hour pain relief. Oxycodone has one of the best bioavailabilities when taken orally with upwards of 87% of it available orally. Whether or not the new OP's work for you is an individual thing, some will find no difference in the new formulation while others can not or more likely WILL NOT tolerate it for a variety of reasons.

Oxymorphone: Opana; Synthetic opiate. *NOT A COMBINATION of OXYCONTIN AND MORPHINE* just because the name sounds like that does not mean thats hows its made, anyone who said or believes that is just plain ignorant and poorly informed. Roughly 7x the potency of morphine with just 1.4mg being equivalent to 10mg oral morphine. However while it may being exceptionally potent it has one of the lowest bioavailabilities amongst opiates, just 10-30% is absorbed when taken orally, which answers some of your question as to why people want to snort, inject or rectally administer this medication. Snorting increases both how much of the medicine and how quickly is absorbed into the bloodstream, while more dangerous it does offer the full spectrum of benefits offered by this medicine. The ER formulation of Opana contains what is known as the TIMERx system, which is the mechanism that traps the oxymorphone within the binder/filler making it nearly impossible to inject. Little known fact was kind of the OxyContin of the 70's amongst pill junkies; they were called blues and were highly sought after because of how easily they were crushed, dissolved and injected, much in the way that can/is done with Diluadid pills.

Fentanyl: Sublimaze, Actiq, Duragesic; Synthetic opiate roughly 50-100x the potency of morphine with just .1mg-.2mg being equivalent to 10mg morphine. Fentanyl is an ultra-short acting opiate lasting on average 1.5-2hrs, which is why it is most commonly delivered transdermally (via contact with skin) over the period of 2-3 days with a continuously worn patch as oral doses would be very small and require constant re-dosing. Many find that the slow absorption thru the skin doesnt allow them to fully feel the effects of this medicine while others find it overpowering by the 2nd day and take it off prematurely. And when referring to Fentanyl it is important to note that you are talking MICROgrams and not Milligrams. A 75mcgrm patch for instance has 7.5mg that is released over the period of 72 hours. Roughly 100micrograms per hour.

*Important Reminders*
Its important to remember that while Opana (oxymorphone) is well over 2x the potency of OxyContin(oxycodone) their bioavailabilties vary greatly. While with Oxycodone you can expect to get about 90% of the medicine with oral administration, when taking Opana remember that only 10-30% will be absorbed when taken orally. This means that if you take 80mgs 2x daily for 160mg, you will have gotten upwards of 144mg of the drug.
On the other hand if your taking 40mg Opana 2x daily for a total of 80mg and you got at best 30% oral bioavailability you will realistically only have gotten about 24-25mg of the drug. And since opana is a little over 2x the potency of oxycontin you will have ingested roughly less than half the painkilling ability of the OxyContin.

This is a helpful chart when you and your doctor are considering changing medication, so you stay properly medicated.

I really hope this helped some and help to clear up some confusion. I openly welcome anyone to challenge my details and findings and i will be more than willing to make adjustments to my info as needed, but i put this up in response to some blatantly misinformed people so i hope you reconsider your assumptions (oxymorphone being morphine and oxycodone) and try to lend better advice in the future.


*Added note*
This has nothing to do with drugs, but Christianity DOES NOT comprise 80% of the worlds religion, as someone else previously showed you with a source, Christians comprise roughly 2.2 billion or just a little under 1/3 of the worlds population. So your information is grossly inaccurate.

PLEASE PEOPLE LETS STRIVE FOR ACCURATE INFORMATION! KNOWLEDGE is POWER!

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172

I did not think Opana worked well at all. I have had RSD for over three years and it was one of the most worthless medications I have tried thus far. I was prescribed 20mg time release and I actually asked my doctor to put me back on Roxycodone 15mg which I take 6 x daily and it works wonders. I really don't know what the big fuss is about with this Opana stuff. I guess different meds work different for different people so if someone gets relief from this I am so glad to hear it. However, it wasn't the med for me.

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173

Thank you for this MUCH needed information! I printed it out and will use it as a reference!! My doctor prescribed 20 mgs of Opana, I haven't started it yet, I want to try it when I don't have to drive, I don't know how its going to effect me yet! I have been taking 325/10 of Percocet for over 2 years now, and I have to keep taking more and more because of the pain, I am praying that Opana is the answer! My doctor did give me the percocet for breakthrough pain..

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174

To attempt an answer to your question, from a long term chronic pain patient. I've been one just about every pharmaceutical used for pain. My guess as to why they don't use chronic pain patients on the trials is just due to tolerance. They could give me 40 mg and not only would it fail to relieve pain, it would put me into withdrawal too. After taking up to 320 mg of OxyC's a day, there would be no way for them to judge what the drug at low levels would even do to me. Finding chronic pain patients that have not been on one narcotic or another prior to entering a trial would be pretty difficult. Just seems logical that the tolerance of the patient would significantly skew the data.

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175

well op only goes up to 40mg so you doctor can not give you 60mg an its not cheap the

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176

is opana more or less harmful than oxycontin on your body & body organs

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177

To answer a quick question about Oxycontin vs, Oxymorphone or Opana requarding toxicity, they re quite similar in the their toxicity both can easily cause fatal resporatory depression and both hav minimal liver and kidney toxicity when compared with more toxic NSAIDs like tylenol ect. In strict terms of an overdose oxycodone would have slightly higher risk assumimg oral consumption due to its higher bioavailability

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178

I'm 18 have fibromyalgia, intractable pain, degenerative deterioration of the spine, bursitis of the right hip. Iv been on opiates since iv been 11 started with 10mg norco (which is vicodin with 325 tylonal) and started taking it 3 times a day and was up to the point where i was taking 12 a day, then i was taking 10mg percs, moved up to 15 mg roxies then they added 30mg oxycontins 3 times a day, then i desided to try and taper myself off pain meds completely at age 15 because it was scary and my tollerance was just to high.at 16 went back on the pain meds because i just couldnt take the pain and tried to start with lower dosed ones like nucynta 100mg, ultram taking 250mg at a time then went back to the 10mg norco moved back up to the 10mg percs then they added the 30mg oxycontin back it was just a horrible cycle well last october i had a bad flair up and was scared because my doctors didnt really communicate with me they just throw scripts at me well i found a good doctor who put me on 30mg ms-contin 3 times a day with up to 2 15mg MSIR (morphine sulfate instant release) well now Im going on 30mg opana er and keeping the 15mg MSIR for breakthrough im very frightend of this after reading all the posts here but im hopeing for the best because the morphine just doesnt work and i hate the way the Oxycontin makes me feel and the personality changes. I just dont know what to do and i need some advice because i dont want to opt to have surgery at this age... this hole opiate scene just scares me and i understand there is a difference between being physically dependent and being a addict i just dont want to fall down the path of being a addict and abusing medication.
My current med list is
Cymbalta 90mg a day
lyrica 225mg 2x a day
Ms-Contin 30mg 3x a day
MSIR (instant release morphine) 15mg as need for BT
Mobic 15mg once a day
Zanaflex (tizanidine) 4mg 3x a Day
Adderall XR 30mg Once a day
BusPar 7.5mg 2x a day
Trazodone 50mg at bedtime for sleep
Please someone have input

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179

opana's are by far the best thing for pain relief since they got rid of oxycontin. I personally find Opana's to be twice as good as my old oxy's, im glad they changed them and would not like to go back. Opana 40mg's are on some websites, and from my personal expierience, twice as strong as my old Oxy 80's...and thats saying something ;)

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180

stick with opana's...trust me dear

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