Muscle/nerve Ache With Eliquis And Niacin Or Statin (Page 8)

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Since starting Eliquis, I have felt much stiffer and sore in the mornings and during the day with muscle tightness in my neck and back affecting my upper arms. A general sense of early aging that is unpleasant. Anyone else with these symptoms?

206 Replies (11 Pages)

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141

Thank you, Margie. One word of advice. Be patient when you discontinue the Eliquis. It may take some time to reverse the muscle damage like I experienced. Everyone is different, but this may take a few weeks or so to get back to normal. Just my opinion here.
It does appear that age is a factor in increasing the risk of problems with Eliquis and possibly Xerelto. This is my gut feeling from all the posts I have reviewed. So this is more a guess than anything else.

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142

Thank you. I will remember that. As for age being a factor, i am 75 so that would qualify me lol

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143

I've taken Eliquis for 2 months. Now I have severe back muscle and neck muscle pain. After doing some sleuthing, I found "musculoskeletal pain and muscle spasms" listed among the side affects; and just below that paragraph was a list of "Metabolic" side affects including (ta-da!!) hypokalemia (low potassium), which of course, would cause muscle pain and spasms as well as the fatigue symptoms, etc. noted by others who are taking Eliquis. The logic is compelling to venture a guess that Eliquis apparently messes with the body's electrolytes, particularly potassium, which is vital for muscle function. Thus, also, shortness of breath, since the low potassium affects also the heart muscle!

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144

Thanks for the input, Wade. Yes, Eliquis does mess with our muscles, just as you are experiencing. And it also affected my breathing, but I think it was due to muscle involvement that affects the breathing process. Seems to be a muscle issue akin to that caused by statins. Just my guess here, but appears similar.
I have been switched to Coumadin, 5 mg, for about 6 weeks now, and I am much better. But still a residual muscle tightness, mostly in my neck and shoulders. I do feel like I am about 90%. Hope all goes well with you.


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145

I am 58 and have a auto immune disease also with my AFIB. Elequis made my pain jump from a 3 to a 9 on the pain scale and that was only 3 days after starting it. Stoped it and pain was much more manageable.

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146

Judy - I noticed your post was from 2015. Curious, I am in the same boat, blood clot from Hormone Replacement, on Eliquis for six months, stiff joints - omygosh. Feel like I have aged 20 years, too. Did it resolve? How long? I have been off Eliquis now for 10 days. Thank you.

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147

I'm checking out the effects of Eliquis on cell wall permeability. I woke up at 3 a.m. thinking I had an aneurism or hernia or the return of my cancer, all the diagnostics came up negative for those. We raced to the hospital. After almost six hours in the ER, blood work and CT scan, the doctor told us that the only thing left as the causate of the extreme pain in my groin was musculo-skeletal issues, which developed after about 2 weeks on Eliquis. We read on the Eliquis website that Eliquis causes low potassium, but my blood potassium level was o.k., so that brings up the question: So., if my blood potassium level is o.k., perhaps the potassium not getting into the muscle tissues, and if not, why not? My guess is that the Eliquis (which we've been told works on the cell walls of the platelets to make them 'slippery' so they don't clot), perhaps has a similar effect on the permeability of the cell walls of muscle tissue, perhaps blocking the uptake of potassium (and other significant electrolytes, such as magnesium) from the blood. Therefore, the pain and dysfunction of muscles begins. That's only my theory, so I need to investigate more. I need to talk to a cytologist. I just know that if you start messing with the body's electrolytes, all kinds of mayhem begins.

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148

I am having a lot of pins and needles in my feet legs and fingers recently and am wondering whether it could be the Apixaban. Does anyone else have this. I'm a bit paranoid that I may have MS.

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149

Hi. I always keep up to date with this website, and I can tell you it's NOT in your head. This problem is very real.

I started on this over 2 years ago and wish I never had. I do suffer from Spinal Stenosis and this makes you think it's all related to the spinal problem however I started to develop pins and needles at the fingertips as though I burnt myself or after getting my husband to look at finger tips because I had convinced myself that there were bits of metal in them this went on and on. So now symptoms are burning in feet toes and tips of fingers.

BUT now for something much worse as if that's not enough I attend dentist every 4 months on a dental plan and my gums are so sore the only reason I can find is this Eliquis has caused the problem something else to add to the list. A drug that has no antidote and causes such problems well that tells you something does it not?

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150

WhaT did your dentist say? All my teeth ache terribly at times now on eliquis. Along with entire body especially if I do anything more than walk and breathe!! Is there any dental concern other than pain?? Thank you! This has been going on for a yr and a half! Since eliquis.

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151

I visit the dentist every 4 months just for check up and usual polishing. I had spoken to him about bleeding gums and he gave teeth the scaling and told me not to be afraid of any bleeding while brushing.

When I went abroad in July/Aug I only used bottled water to rinse simply because I go from a very soft water area to one that's full of minerals, but this time my teeth were hurting like hell, and when I came back home, decided to use good toothpaste and Corsodyl mouthwash. The mouthwash takes your taste for food away so I have been using it just at night so perhaps it would be better to use it at least twice a day.

Last night had frequency of urine and to say tested it with urine sticks shows a good bit of blood in it but told this is a side effect of Eliquis. So many problems with this drug and I ache all over have not had blood work done for just over a year, so I will contact the surgeon to remind them that it's time, and once I get results I will post it on this site.

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152

I don't know Stef but I am doing the same thing and have been for a few years and the cramps/spasms are gradually getting to be an every night all night thing that is wearing me totally out, I do not take Eloquis or Statins. I have had Levaquin in the past that caused the same symptoms and there is a black box warning that it and it's family of antibiotics can cause permanent tendon damage.
I went to a Neurosurgeon who did an MRI and it said that I have a buldging disc and spinal stenosis in my lower back and the stenosis in two more areas also. From the pain I would say middle and neck area. His nurse asked if I would like to schedule steroid shots in my spine to alleviate some of the pain. I said no, I
will forego those. I am allergic to corn and the allergy gets quickly worse all the time, and I'm fearful of getting corn in the glucose they use. I could die from anaphylaxis while they have me sedated for the shots. I have had two surgeries before for bulging disc and stenosis in my low spine. I have read that spinal stenosis can cause leg cramps. Mine was nothing like this before. I have to have some relief. Both my legs go into spasms at the same time most nights, and that includes the entire leg, front and back from hips to toes. Sometimes my hands and even my ribcage spasm and cram. If surgery will give me relief, I will have another one. But I do not want to have one and wake up to the spasms still. So I am trying to rule things out first.
I hope you find out the cause of yours soon. If you do, please post here. Thanks, Bren.

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153

Re: Wade (# 143) Expand Referenced Message

So, then getting more electrolyte s and potassium would help or not, do you think? If it is not metabolizing? Suddenly feeling my parents age! Really discouraging, and pain is sleep depriving.

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154

I have been on Eliquis since Aprtil, PAin in lower back and neck.going to physivcal therapy.but may be the e liquis. Also very weird smell in Urine and bowels and I know tat is the eliquis.any help out there.

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155

Re: virginia (# 154) Expand Referenced Message

You are right since taking this I have the same problem but just watch out for pink or different colour in your urine and report to your doctor this can be serious .

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156

Have terrible pain. Muscle soreness, nerve pain, weakness. Had back surgery yr. ago and fibro for years. Had irregular heart beat put on Metoprolol. Had blood clot after surgery. Put on Eliquis. Have been worse since put on these two medications. Are they the culprit? I don't know and wonder if anybody does. The doctor gives us meds to make us better but do they really?

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157

I was taking Eliquis for six months and had no problem until about three weeks before I went off it experiencing terrible joint pain. I went off the Eliquis as scheduled on August 1st. It took an additional three weeks to get it out of my system. I drink water and more water and more water and I'm finally back to normal. No joint pain. I can jump out of bed in the morning. I can walk. I can do all my things, so I know for a fact it was the Eliquis in my system.

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158

WOW! I'm only 45 and I've taken cumadin for 16 years. This year I switched to Eliquis. As many people have described, I feel like my feet have aged 30 years. It has been awful. I started to realize it progressed so quickly since about when I started this med. I am going to have to do something for my feet. I just started wondering if anyone else has had any problem like this. I have to make myself walk in the morning. Everything points to planter fascilitis. That may just be it, but why so crippling so fast? I will also talk to my doctor. Thank you for sharing your experiences!!!

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159

Re: MB (# 158) Expand Referenced Message

That is exactly how I felt. My feet even my toe joints it was horrible I dreaded stairs etc. I am fit always have been weigh 135 and strong but that drug crippled me. So...as I said in my earlier post, I went off on august1 as scheduled. Did a detox anti inflammatory food no sugars and g
No gluten. Drank at least 64 oz water. Took three weeks. I am normal. Ran down stairs today just to do it cuz I could again!!!!! Good luck to you and maybe my experience will help you.

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160

Re: January (# 159) Expand Referenced Message

Yes, I too have my life back after getting off Eliquis 2 months ago. As I said before, it made me feel like I aged 20 years, and my neck and shoulders were stiff and painful at times, and legs felt like dead weight. Switched to Coumadin, and while it took a little timie, I can now run forever on my treadmill. Little or no muscle pain. So everyone must be aware that these NEW blood thinners are bad news for a lot of folks. And most doctors do not have a clue. Report these incidents to FDA on the MedWatch form, because almost all doctors WILL NOT REPORT THESE BAD SIDE EFFECTS. TAKE CHARGE OF YOUR HEALTH!!!

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