Methadone Mallinckrodt

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I take 30mg of methadone for 2 ruptured disc's L4,L5 along with 40mgs of hydrocodone for 5years now,I have been getting the mallinckrodt but this time pharmacy gave me the asc116 round tabs and I noticed my pain breaking through sooner and having to take them early than the mallinckrodt.Was wondering if there was a difference in them I thought by law they would have the same milligrams in them.

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1

Hello, James! How are you? I am very sorry about the problem you're experiencing.

Under the Hatch-Waxman Act of 1984 generics are allowed to differ from the name brand by as much as plus, or minus 20% of the active ingredient(s), however, sometimes issues occur, because generics do not have to measure against each other, only against the name brand. Thus, there's a chance that this one might be lower in the active ingredient than the one you were taking, before.

This law was put in place to help bring generics to market faster, for those that don't have insurance, since the differences usually amount to very tiny differences. Most people never notice an issue, but someone taking a medication for a long period of time, or who is very sensitive to any change in medication can sometimes run into issues with their efficacy.

How are you doing, now? Has there been any change?

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Thanks, Verwon for the reply the information was very helpful I called my pharmacy and they said they would fill my prescription with the mallinckrodt next time they said they carry both the ASC and mallinckrodt,to just request it when I get them filled, nothing has really changed my pain seems to still break threw earlier on the ASC's and I have to take them alot earlier than the Mallinckrodt ,after going threw this I guarantee I will ask or request the Mallinckrodt next month and Everytime. I only have a few more days left till my pain management appointment it's just been inconvenit to say the least...thanks for info, James

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3

I was switched to Mallincrock from Watson for Norco 10/325 and to a generic brand for Opana 20mg ER, both suck, no where near when I was taking Watson and Purdue brand, I'd say 1/2 the efficacy.

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